351 research outputs found
Novel Dialogue 1.4: Feral Fiction: Catherine Lacey and Martin Puchner (JP)
No full textNovel Dialogue sends Martin Puchner (polymathic author of The Written World and most recently The Language of Thieves) out to speak with Pew author Catherine Lacey. They go a-wandering. Lacey's earlier works include a 2018 collection of short stories, Certain American States, and two novels: The Answers in 2017 and 2014's Nobody is Ever Missing, a delightful road novel set in New Zealand-always a sure way to win John's admiration. Martin starts by noticing the feral through-line in Catherine's work, a way that people escape or withdraw from socialization. And things go rapidly uphill and downhill from there. In short a rollicking rhythm prevails-you may want to listen while out rambling yourself. Even though Catherine proclaims "we are all housecats now.
Callers’ experiences of contacting a national suicide prevention helpline
No full textBackground: Helplines are a significant phenomenon in the mixed economy of health and social care. Given the often anonymous and fleeting nature of caller contact, it is difficult to obtain data about their impact and how users perceive their value. This paper reports findings from an online survey of callers contacting Samaritans emotional support services. Aims: To explore the (self-reported) characteristics of callers using a national suicide prevention helpline and their reasons given for contacting the service, and to present the users’ evaluations of the service they received. Methods: Online survey of a self-selected sample of callers. Results: 1,309 responses were received between May 2008 and May 2009. There were high incidences of expressed suicidality and mental health issues. Regular and ongoing use of the service was common. Respondents used the service for complex and varied reasons and often as part of a network of support. Conclusions: Respondents reported high levels of satisfaction with the service and perceived contact to be helpful. Although Samaritans aims to provide a crisis service, many callers do not access this in isolation or as a last resort, instead contacting the organization selectively and often in tandem with other types of support
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Open Standards for Sensor Information Processing
No full textThis document explores sensor standards, sensor data models, and computer sensor software in order to determine the specifications and data representation best suited for analyzing and monitoring computer system health using embedded sensor data. We review IEEE 1451, OGC Sensor Model Language and Transducer Model Language (TML), lm-sensors and Intelligent Platform Management Inititative (IPMI)
Cranberry (Vaccinium macrocarpon) extract reduces tumour necrosis factor alpha-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in vascular smooth muscle cells
No full textNatural 'bioactive' factors have the ability to attenuate atherogenesis in in vitro and in vivo models. The effects of cranberry on the expression of two inflammation-linked enzymes, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), were examined in aortic smooth muscle (A7r5) cells in the absence/presence of tumour necrosis factor alpha (TNF alpha). Western blot analysis revealed that while cranberry did not affect base-line protein expression of COX-2, it did reduce base-line levels of iNOS protein. Cranberry was able to effectively reduce the T'NF alpha-stimulated induction of both these enzymes. This reduction was observed after 6, 12, and 24 hours pre-exposure to cranberry prior to exposure to TNF alpha., and after a 6 hour co-incubation of cranberry with TNF. NFkB (a transcriptional regulator of COX-2 and iNOS) expression was assessed in response to cranberry treatment. Base-line cytosolic, I levels of the phosphorylated form of NFkB (p-NFkB) were reduced following exposure to cranberry. Cranberry also reduced TNF(alpha-stimulated p-NFkB levels. Taken together, these results suggest that cranberry may partly modulate the inflammatory response observed in atherosclerosis by affecting the expression of COX-2 and iNOS, and that this modulation may occur through interaction with the NFkB; transcription factor. The temporal/ signal transduction mechanisms involved are being studied
Shifting ground: Can community development loan funds continue to serve the neediest borrowers?
No full textCommunity development financial institutions (CDFIs) are designed to improve economic conditions for low-income individuals and communities by providing a range of financial products and services that often are not available from mainstream lenders and financiers. ; Part I of this paper reviews CDLF origins, structures, and current activities. Part II discusses the field’s historic sources of subsidized capital and why they have shrunk. Part III reviews potential new sources of capital and the organizational ways that CDLFs are responding to their changed environment. The paper concludes with recommendations for CDLFs, funders, and policy makers.Community development ; Loans
Genomic Diversity and Abundance of LINE Retrotransposons in 4 Anole Lizards
No full textabstract: Vertebrate genomes demonstrate a remarkable range of sizes from 0.3 to 133 gigabase pairs. The proliferation of repeat elements are a major genomic expansion. In particular, long interspersed nuclear elements (LINES) are autonomous retrotransposons that have the ability to "cut and paste" themselves into a host genome through a mechanism called target-primed reverse transcription. LINES have been called "junk DNA," "viral DNA," and "selfish" DNA, and were once thought to be parasitic elements. However, LINES, which diversified before the emergence of many early vertebrates, has strongly shaped the evolution of eukaryotic genomes. This thesis will evaluate LINE abundance, diversity and activity in four anole lizards. An intrageneric analysis will be conducted using comparative phylogenetics and bioinformatics. Comparisons within the Anolis genus, which derives from a single lineage of an adaptive radiation, will be conducted to explore the relationship between LINE retrotransposon activity and causal changes in genomic size and composition.Dissertation/ThesisM.S. Biology 201
Factors that promote or inhibit the implementation of e-health systems: an explanatory systematic review
No full textOBJECTIVE: To systematically review the literature on the implementation of e-health to identify: (i) barriers and facilitators to e-health implementation, and (ii) outstanding gaps in research on the subject.METHODS: MEDLINE, EMBASE, CINAHL, PSYCINFO and the Cochrane Library were searched for reviews published between 1 January 1995 and 17 March 2009. Studies had to be systematic reviews, narrative reviews, qualitative metasyntheses or meta-ethnographies of e-health implementation. Abstracts and papers were double screened and data were extracted on country of origin; e-health domain; publication date; aims and methods; databases searched; inclusion and exclusion criteria and number of papers included. Data were analysed qualitatively using normalization process theory as an explanatory coding framework.FINDINGS: Inclusion criteria were met by 37 papers; 20 had been published between 1995 and 2007 and 17 between 2008 and 2009. Methodological quality was poor: 19 papers did not specify the inclusion and exclusion criteria and 13 did not indicate the precise number of articles screened. The use of normalization process theory as a conceptual framework revealed that relatively little attention was paid to: (i) work directed at making sense of e-health systems, specifying their purposes and benefits, establishing their value to users and planning their implementation; (ii) factors promoting or inhibiting engagement and participation; (iii) effects on roles and responsibilities; (iv) risk management, and (v) ways in which implementation processes might be reconfigured by user-produced knowledge.CONCLUSION: The published literature focused on organizational issues, neglecting the wider social framework that must be considered when introducing new technologies.<br/
Katherine Philips and Corneille: Of the Importance of Being a Translator
No full textInternational audienceWhile Katherine Philips’ poetry has received a great deal of critical attention in the recent past, her translations of two Corneille plays have been relatively overlooked. When they had been scrutinized, however, it is their political dimension that has been mainly emphasized. Yet both Catherine Mambretti and Peter Beal have alerted us to the historical importance of these translations: Mambretti by showing that Philips was de facto responsible for the first heroic tragedy to be performed in the British Isles, and Beal by reminding us that the publication of Pompey in 1663 was vital in establishing Philips’ fame as a major woman poet. This chapter compares Philips’ translation of Pompey with its 1643 original to assess Philips’ strategy as a translator. It will then show how Philips’ poetry is in turn informed by her reading of Corneille and her experience of transliteration. It is my contention that her intimate knowledge of French literature was instrumental in her self-fashioning as a poet, and that it offered her an alternative, woman-friendly canon with new and fashionable models to imitate. In this respect, it is perhaps no accident that she chose Pompey, a play that had connections with Garnier’s Tragedie of Antonie (1595) – a play which had also allowed another Englishwoman, Mary Sidney, to become a literary author
Correspondence and epenthetic quality
No full textIn some languages epenthetic segments are realized with unmarked features while in others they are copies of nearby segments. To account for this variation, we propose that epenthetic elements can be in a relation of Correspondence with other output segments, analogous to reduplication. This approach is shown to account for both cross-linguistic and language-internal variation in epenthetic featural quality. We examine a variety of cases of epenthesis, focussing on cases of copy epenthesis and on languages where epenthetic quality varies in different contexts.The definitive version was published in Proceedings of the Proceedings of AFLA (Austronesian Formal Linguistics Association) VI (1999) and is available at http://twpl.library.utoronto.ca/index.php/twplKitto, C. and de Lacy, P. (1999). Correspondence theory and epenthetic quality. In C. Kitto and C. Smallwood (Eds.) Proceedings of AFLA (Austronesian Formal Linguistics Association) VI. Toronto: Toronto Working Papers in Linguistics, 181-200This study was supported by National Science Foundation under grant SBR-9420424.Note for the Rutgers Optimality Archive version: This version differs from the published one in that we have added a number of sections. These sections are marked by a vertical double line running down the left edge of the page
Human trafficking in BC from 2000 to 2016: Government personnel and front-line service providers' observations
No full textPublic discourse on human trafficking in British Columbia has shifted from a primarily international narrative in the early 2000s, towards a more complex narrative that considers both international and domestic crimes in 2016. Based on fourteen semi-structured qualitative interviews, this research compares government personnel and front-line service providers’ observations about the narrative shift, as well as their overall understandings of what human trafficking crimes look like in the province. The findings indicate that an individual’s understanding of who is most commonly victimized, as well as their perceptions about overall rates of victimization are largely influenced by their professional interactions with victims. Education was perceived by both data groups to be a key component in developing more effective anti-trafficking strategies; however, participants divergent understandings of who is most at-risk continue to confuse the human trafficking debate and many of the structural causes of the crime remain unaddressed.human traffickingBritish Columbiagovernment personnelfront-line service providersvictim
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