180,631 research outputs found
Caderno Escolar, Doering, 4º ano primário, 1959, RS
No full textO caderno é pautado de encadernação tipo canoa. Está preenchido com caneta tinteiro preta e lápis, há correções em caneta vermelha. Contém 20 páginas. Item digitalizado por Nícolas Giovani da Rosa.Este caderno de Matemática, de 1959, pertenceu a Claus Ivo Doering e foi usado no 4º ano do Curso Primário na Escola Sinodal Visconde de Porto Seguro, em Ibirubá - R
Promoting rational antibiotic prescribing for non-complicated infections: understanding social influence in primary care networks in Germany
No full textContains fulltext :
218904.pdf (Publisher’s version ) (Open Access)BACKGROUND: Primary care networks in Germany are formalized regional collaborations of physicians and other healthcare providers. Common goals are optimized healthcare processes and services for patients, enhanced communication, agency for professional concerns and strengthened economic power. In the ARena study (Sustainable reduction of antibiotic-induced antimicrobial resistance), 14 primary care networks in two federal German states aimed to promote appropriate antibiotics use for acute non-complicated infections by fostering awareness and understanding. Factors related to the role of primary care networks were to be identified. METHODS: For this study, audio-recorded telephone interviews were conducted with physicians, non-physician health professionals and stakeholder representatives. Pseudonymized verbatim transcripts were coded using thematic analysis. In-depth analysis was based on the inductive categories 'social support', 'social learning', 'social normative pressures' and 'social contagion' to reflect social influence processes. Data generated through a survey with physicians and non-physician health professionals were analyzed descriptively to foster understanding of the networks' potential impact on antibiotic prescribing. RESULTS: Social influence processes proved to be relevant regarding knowledge transfer, manifestation of best-practice care and self-reflection. Peer communication was seen as a great asset, the main reason for membership and affirmative for own perspectives. All interviewed physicians (n = 27) considered their network to be a strong support factor for daily routines, introduction of new routines, and continuity of care. They utilized network-offered training programs focusing on best practice guideline-oriented use of antibiotics and considered their networks supportive in dealing with patient expectations. A shared attitude combined with ARena intervention components facilitated reflective management of antibiotic prescribing. Non-physician health professionals (n = 11) also valued network peer exchange. They assumed their employers joined networks to offer improved and continuous care. Stakeholders (n = 7) expected networks and their members to be drivers for care optimization. CONCLUSION: Primary care networks play a crucial role in providing a platform for professional peer exchange, social support and reassurance. With regards to their impact on antibiotic prescribing for acute non-complicated infections, networks seem to facilitate and amplify quality improvement programs by providing a platform for refreshing awareness, knowledge and self-reflection among care providers. They are well suited to promote a rational use of antibiotics. TRIAL REGISTRATION: ISRCTN, ISRCTN58150046. Registered 24 August 2017
Fouilles archéologiques de M. Ubbelohde-Doering au Pérou.
No full textR. H. Fouilles archéologiques de M. Ubbelohde-Doering au Pérou. In: Journal de la Société des Américanistes. Tome 34, 1942. p. 234
The complex phenomenon of dysrational antibiotics prescribing decisions in German primary healthcare: a qualitative interview study using dual process theory
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218919.pdf (Publisher’s version ) (Open Access)Background: Antibiotic prescription rates in primary care in Germany are moderate, but still considered too high. The ARena study (Sustainable reduction of antibiotic-induced antimicrobial resistance) was initiated to foster awareness and understanding of the growing challenge and promotes rational antibiotics use for acute, non-complicated and self-limiting infections. Methods: The present study was performed as part of the process evaluation of the ARena study. Interviews were conducted with a purposive sample of physicians participating in the ARena study to identify factors relevant to primary care physicians' decision-making when prescribing antibiotics for acute non-complicated infections. Generated data were audio-recorded. Pseudonymized verbatim transcripts were coded using a pre-defined framework. The Dual Process Theory was applied to provide understanding of individual health professional factors that induce dysrational prescribing decisions. Results: Based on medical as well as non-medical considerations, physicians developed habits in decision making on antibiotics prescribing. They acknowledged inadequate antibiotics prescribing for acute, non-complicated infections in situations involving uncertainty regarding diagnosis, prognosis, continuity of care, patient expectations and when not knowing the patient. Educative efforts empowered physicians to override habitual prescribing. A theory-driven model provides transparency as to how dysrational prescribing decisions occur and suggests remedy by providing new experiences and new recognizable patterns through educative efforts. Conclusions: Educational interventions may only change prescribing behaviours if they result in active rational rather than routine-based decision-making on antibiotics prescribing. Trial registration: ISRCTN, ISRCTN58150046
Organic–Inorganic Polyimides with POSS Cages in the Main Chains: An Impact of POSS R Groups on Morphologies and Properties
No full textTwo well-defined POSS diamines were synthesized with
phenyl (Ph)
and iso-butyl (i-Bu) POSS trisilanols
as the starting compounds. This approach involves the protection and
deprotection of silanol hydroxyl groups with phenylboronic acid and
pinacol, followed by the silylation of silanol hydroxyl groups with
mono- and dichlorosilanes. With this route of synthesis, two well-defined
divinyl POSS macromers were obtained, as evidenced by 1H, 29Si NMR, and mass spectroscopy. These two divinyl
POSS macromers were further functionalized into well-defined POSS
diamines via the Heck reaction with p-bromoaniline. The successful synthesis of POSS diamines enabled
the synthesis of organic–inorganic polyimides with the POSS
cages in the main chains. More importantly, the syntheses of these
two POSS diamines allowed the examination of the effect of POSS R
groups (i.e., Ph and i-Bu) on the
morphologies and thermomechanical and dielectric properties of organic–inorganic
polyimides. Notably, the types of POSS R groups exerted a profound
impact on the morphologies and properties of the organic–inorganic
polyimides
Dana Peterson and Vanessa R Panfil (Eds.) (2014). Handbook of LGBT Communities, Crime, and Justice. Springer
No full textBruno Doering reviews Handbook of LGBT Communities, Crime, and Justice by Dana Peterson and Vanessa Panfil (Editors)
Coating stent materials with polyhedral oligomeric silsesquioxane-poly(carbonateurea)urethane nanocomposites
No full textThe long-term efficacy of coronary or peripheral stenting is limited by in-stent
restenosis (ISR), which occurs in 15 to 30% of patients and is attributed primarily to
neointimal hyperplasia. By adding a drug-eluting coating, this rate has been reduced
to about 5% or less. However, recently longer-term follow-up data has highlighted
problems with drug-coated stents, including late stage thrombosis. A bio-stable
poly(carbonate-urea)urethane has been used for stent coating and the surface
properties of the polymer have been optimised by incorporating the polyhedral
oligomeric silsesquioxane molecule. These POSS polymers improve the adhesion and
the growth of endothelial cells. The work described in this thesis, presents an
innovative approach in self-expanding/balloon expandable coronary stent design that
incorporates a NiTi/stainless steel alloy scaffold with a polyhedral oligomeric
silsesquioxane- poly (carbonate-urea) urethane nanocomposite polymer (POSS-PCU)
coating. Electrohydrodynamic spraying and ultrasonic atomization spraying of the
non-biodegradable nanocomposite polyhedral oligomeric silsesquioxane (POSS)
polymer have been investigated in detail for coating metallic stent materials and
compared with dip coating. Because of the tight geometry of coronary stents, these
new coating techniques have been shown to offer advantages over traditional coating
techniques. These advantages include, reduced polymer consumption, precise coating
thickness as low as 10 μm and a highly controllable spray which leads to consistent
reproducible results. However, poor adhesion, or bond deterioration over the lifespan/
deployment of the device could reduces the efficiency and could impart even more
complexity to the implant including formation of debris which can induce thrombus
formation. Changing the surface physical property/chemical composition through the
proposed protocol has been shown to increase the bonding strength by up to three
times. This study has identified a new process and conditions which can be used in
stent coating research
The Mixing Efficiency of Open Flows
No full text1 online resource (PDF, 15 pages, includes illustrations)Thiffeault, Jean-Luc; Doering, Charles R.. (2010). The Mixing Efficiency of Open Flows. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/180793
Covalently engineering novel sandwich-like rGO@POSS nanofillers for high-performance dielectric energy storage of PVDF film capacitor
No full textWith the development of modern electronic and electrical industry, it is still a great challenge to develop poly (vinylidene fluoride) (PVDF) based dielectric capacitors with high energy storage capability. Herein, a novel sandwich-like nanofiller was constructed via covalently grafting polyhedral oligomeric silsesquioxane onto graphene oxide nanosheets (GO@POSS), further PVDF/rGO@POSS film were fabricated via solvent-casting and in-situ thermal reduction processes. The results indicated that the grafting of POSS promoted the uniform dispersion of nanofillers to realize strong interfacial interaction with PVDF matrix. The optimal PVDF film containing 0.75 wt% rGO@POSS (0.75PGP-60) exhibited larger dielectric constant (epsilon r = 13.32) and higher breakdown strength (Eb = 339.1 MV m- 1), thus resulting in synchronous improvements on energy density (Ue = 5.42 J & sdot;cm- 3) and charge-discharge efficiency (eta = 73.1 %), which increased by 95.0 % and 19.4 % compared to pure PVDF, respectively. Meanwhile, it presented excellent cycling stability with 97.6 % energy density retention after 10000th cycles. The improved energy storage capability was attributed to reasonably-designed sandwichlike nanofiller: the formation of rGO micro-capacitors raised the dielectric constant of PVDF nanocomposites, while the insulative POSS layer helped to improve its breakdown strength and decrease its dielectric loss. The current work provides a novel and efficient paradigm to design PVDF nanocomposites with promising dielectric properties and energy storage capacity, and further contributes to broadening the practical applications of advanced dielectric capacitors
POSS Fulleropyrrolidines
No full textThe first reported examples of polyhedral oligomeric silsesquioxane (POSS) cages containing a fulleropyrrolidine species are reported herein. Monosubstituted POSS-dioxalane species were synthesized through the hydrosilylation of a silyl-dioxalane with mono-vinyl substituted POSS. Subsequent deprotection yielded the desired aldehyde functionality. An alternative synthetic pathway, involving the nucleophilic substitution of mono-benzyl chloride POSS with 4-hydroxybenzaldehyde yielded the desired aldehyde functionality. Each mono-aldehyde POSS was then reacted with N-methylglycine and C60 to yield the desired POSS fulleropyrrolidines. The prepared compounds were characterized by multinuclear NMR, electrospray mass spectrometry, UV-VIS, fluorescence and optical power limiting measurements
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