5,077 research outputs found

    Contro la funzionalizzazione della contrattazione collettiva. Riflessioni sul pensiero di Mario Rusciano

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    L'autore riflette sul pensiero di Mario Rusciano in punto di funzionalizzazione della contrattazione collettiva.The author reflects on the thought of Mario Rusciano in relation to the subject of the functionalisation of collective bargaining

    Innovazioni terapeutiche nella proctite attinica cronica: valutazione della radiofrequenza endoscopica come alternativa alle tecniche tradizionali.

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    1. Abstract Introduction Chronic actinic proctitis is a late complication of pelvic radiotherapy, caused by ischemic microvascular lesions that lead to chronic rectal bleeding, anemia, and a reduction in quality of life. Traditional therapies, including argon plasma coagulation (APC), although effective, are burdened by ulcerations and stenosis. Materials and Methods Radiofrequency ablation (RFA), already successfully used for esophageal lesions, provides controlled and superficial necrosis, promoting mucosal re-epithelialization. The aim of the study is to evaluate the efficacy and safety of RFA in the treatment of refractory chronic actinic proctitis, comparing it with conventional endoscopic techniques. Selected patients were treated with a BarrxTM through-the-scope catheter, applying an energy of 10 J/cm2 (300 W). Endoscopic follow-up, using white light and narrow-band imaging (NBI), monitored re-epithelialization and the onset of complications. Results: Between January 1, 2023, and October 31, 2024, 15 patients with symptomatic CRP refractory to conventional medical therapy were enrolled. All patients underwent endoscopic treatment with RFA and subsequent follow-up until October 31, 2025. Control of rectal bleeding was achieved in thirteen patients (86.6%) after 1 or 2 sessions. In the remaining two cases, a significant reduction in bleeding was observed, although not complete remission. Ten patients received a single session (66.6%), while five patients required a second application after 6-8 weeks (33.3%). The complete remission of bleeding observed in 86.6% of patients and partial remission in the remaining 13.4% confirm the hemostatic efficacy of RFA, in line with the findings of major international trials. The progressive improvement in hemoglobin levels and the elimination of transfusion requirements within the first few months after treatment indicate an early and lasting clinical response. Endoscopically, the complete re-epithelialization of the rectal mucosa, with regression of telangiectasias and normalization of the vascular pattern, documented in all patients at the 24-month follow-up, demonstrates that the healing achieved is not only morphological but also functional. The complete absence of ulcerations, stenosis, or late fibrosis confirms the precision and selectivity of radiofrequency-induced superficial ablation, which allows for the preservation of the structural integrity of the rectal wall. Discussion This study represents one of the most recent experiences of the application of endoscopic radiofrequency (RFA) in the treatment of refractory chronic actinic proctitis (CRP), a complex and highly disabling clinical condition that can arise in patients undergoing pelvic radiotherapy for prostate, rectal, endometrial, or cervical cancer. The results obtained in our series highlight the high efficacy of RFA in controlling rectal bleeding and mucosal regeneration, with an excellent safety profile and significant clinical improvement maintained over time. Conclusions Endoscopic radiofrequency has been confirmed as an effective, safe, and minimally invasive method for chronic actinic proctitis, capable of ensuring long-lasting bleeding control and excellent mucosal healing

    Il diritto penale nel canone di Mario Romano

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    This paper deals with the extension and the extraordinary scientific value of the works written by a great Master in Criminal Law, such as Mario Romano. The Author briefly presents some of the most relevant contributions given by Professor Mario Romano to the Criminal Science, first of all his "Commentario sistematico del codice penale" (Systematic Commentary on the penal code), a unique work. Finally, the paper talks about some topics which have been developed inside the work "Studi in onore di Mario Romano" (Studies in Honour of Mario Romano)

    Introduzione, a Mario Tobino, Il Clandestino

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    L'introduzione presenta il libro più ambizioso di Mario Tobino, Il Clandestino, dedicato al racconto della sua esperienza con i gruppi clandestini della Resistenza Viareggina, libro con cui l'autore vinse il Premio Strega, nel 1962, imponendosi all'attenzione del grande pubblico dopo il successo dei libri manicomiali. Una nuova edizione in cui Paola Italia valorizza i materiali inediti dell'Archivio Tobino conservato presso l'Archivio Contemporaneo A. Bonsanti del Gabinetto GP Vieusseux di Firenze,Paola Italia presents an Introduction to the new edtion of Il Clandestino, the most ambitious of Mario Tobino's novels, dedicated to the story of his experience with the groups of the Tuscan Resistance when he was a psichiatric doctor ar Lucca. With this book the author won the Strega Prize, in 1962, attracting the attention of a wide public after the success of his psichiatric books. A new edition where Paola Italia enhances the unpublished material of Tobino Archive preserved in A. Bonsanti Contemporary Archive of G.P. Vieusseux Cabinet of Florence

    L'uno e il molteplice: su Catull. 5

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    In Catull. 5, the author cleverly works out two ancient topoi (‘let’s love, because the night/death is coming’; ‘kisses are the joy of lovers’), gaining a well balanced structure of the poem. In comparison with contemporary Graeco-Roman poetry (erotic epigrams – such as Philod. AP 9, 570 –, the Epitaph of Bion), both themes are handled with a remarkable taste for originality, especially in their ‘numerical’ aspects, in order to put special emphasis on the basic contrast between nox una and basia mille

    Surgical management of endometriosis-associated pain

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    Endometriosis and pelvic pain are associated. However, only half of the subtle and typical, and not all cystic and deep lesions are painful. The mechanism of the pain is explained by cyclical trauma and repair, an inflammatory reaction, activation of nociceptors up to 2.7 cm distance, painful adhesions and neural infiltration. The relationship between the severity of lesions and pain is variable. Diagnosis of the many causes requires laparoscopy and expertise. Imaging cannot exclude endometriosis. Surgical removal is the treatment of choice. Medical therapy without a diagnosis risks missing pathology and chronification of pain if not 100% effective. Indications and techniques of surgery are described as expert opinion since randomised controlled trials were not performed for ethical reasons, since not suited for multimorbidity while a control group is poorly accepted. Subtle endometriosis needs destruction since some cause pain or progress to more severe disease. Typical lesions need excision or vaporisation since depth can be misjudged by inspection. Painful cystic ovarian endometriosis needs adhesiolysis and either destruction of the lining or excision of the cyst wall, taking care to avoid ovarian damage. Cysts larger than 6cm need a 2 step technique or an ovariectomy. Excision of deep endometriosis is difficult and complication prone surgery involving bladder, ureter, and bowel surgery varying from excision and suturing, disc excision with a circular stapler and resection anastomosis. Completeness of excision, prevention of postoperative adhesions and recurrences of endometriosis, and the indication to explore large somatic nerves will be discussed

    In memoriam Mario Napoli

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    L'autore ricorda la vita e le principali opere di Mario Napoli, suo Maestro e illustre studioso del Diritto italiano del lavoro.The author remembers the life and the most important works of Mario Napoli, his Master and one of the leading scholars of Italian labour law

    La libertà da difendere

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    Il contributo costituisce la prefazione del volume curato dallo stesso autore.The contribution is the introduction to the volume, whose editor is the same author

    La vida y pensamiento de Mario Alzamora Valdez

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    In the following lines, the author seeks to pay tribute and simultaneously indicate and show the significance of an illustrious jurist, the Dr. Mario Alzamora Valdez. The author firstly justifies the reason for emphasizing in Alzamora Valdez, then, take us back to the classes that Mario Alzamora Valdez received in the UNMSM and the “Universidad Católica”. To conclude, the author indicates the profiles of Mario Alzamora\u27s procedural thought as well as the location of his doctrines in the history of the Peruvian Procedural Law.En las siguientes líneas, el autor busca rendir un homenaje y a la vez señalar y mostrar el alcance de un ilustre jurista, el Dr. Mario Alzamora Valdez. El autor primeramente justifica el por qué de hacer hincapié en Alzamora Valdez, luego, nos remonta a las clases que recibió Mario Alzamora Valdez en la UNMSM y la Universidad Católica. Para concluir, el autor señala los perfiles del pensamiento procesal de Mario Alzamora así como la ubicación de sus doctrinas en la historia del Derecho Procesal Peruano
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