126,104 research outputs found
Hydrophobic adsorption and covalent immobilization of Candida antarctica lipase B on mixed-function-grafted silica gel supports for continuous-flow biotransformations
Adsorption onto solid supports has proven to be an easy and effective way to improve the mechanical and catalytic properties of lipases. Covalent binding of lipases onto the support surface enhances the active lifetime of the immobilized biocatalysts. Our study indicates that mesoporous silica gels grafted with various functions are ideal supports for both adsorptive and covalent binding for lipase B from Candida antarctica (CaLB). Adsorption of CaLB on phenyl-functionalized silica gels improved in particular its specific activity, whereas adsorption on aminoalkyl-modified silica gels enabling covalent binding with the proper reagents resulted in only moderate specific activity. In addition, adsorption on silica gels modified by mixtures of phenyl- and aminoalkyl silanes significantly increased the productivity of CaLB. Furthermore, CaLB adsorbed onto a phenyl/aminoalkyl-modified surface and then treated with glutardialdehyde (GDA) as cross-linking agent provided a biocatalyst of enhanced durability. Adsorbed and cross-linked CaLB was resistant to detergent washing that would otherwise physically deactivate adsorbed CaLB preparations. The catalytic properties of our best immobilized CaLB variants, including temperature-dependent behavior were compared between 0 and 70 C with those of two commercial CaLB biocatalysts in the continuous-flow kinetic resolutions of racemic 1-phenylethanol rac-1a and 1-phenylethanamine rac-1b. © 2013 Elsevier Ltd
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
PO-0770: The distortions of the dose response functions of dosimeters in the presence of a magnetic field
SU‐E‐T‐126: Non‐Reference Condition Correction Factor KNR of Typical Radiation Detectors for the Dosimetry of High‐Energy Photons
SU‐E‐T‐328: The Volume Effect Correction of Probe‐Type Dosimetric Detectors Derived From the Convolution Model
SU-E-T-502: Dose Perturbation Effects Near Implant Surfaces Caused by Secondary Electron Transport in Photon-Beam Therapy
1. B [Heinrich Beugger] 2. P [Felix Poppe]
Untereinander zwei Knaben im Profil nach linksM. Wchsmut. SculpDie Radierungen stehen vermutlich in Zusammenhang mit Lavater's PhysiognomikGemäss interner Notiz ist oben Heinrich Beugger und unten Felix Poppe aus Otelfingen porträtiertVermutlich aus der Sammlung Leonhard Ziegler zum Egli (1782-1854) Exemplar der Zentralbibliothek Zürich, Graphische Sammlung und Fotoarchi
Seguenzia elegantissima Poppe, Tagaro & Dekker 2006
<i>Seguenzia</i> cf. <i>elegantissima</i> Poppe, Tagaro & Dekker, 2006 <p>(Figures 10–12)</p> <p> 2006 <i>Seguenzia elegantissima</i> nov. spec.—Poppe, Tagaro & Dekker: p. 26, pl. 3, fig. 2. 2008a <i>Seguenzia elegantissima</i> —Poppe & Tagaro: p. 162, pl. 26, fig. 4.</p> <p> <b>Material.</b> Anda 6 (6); AndaDeVos (18); AndaClif3 (7); Tiep 1 (1).</p> <p> <b>Characterization.</b> High spired, H 2.3 mm, W 1.9 mm; P 1.1 whorls, with erect nucleus and two discontinuous spiral ribs, DN 0.11–0.14 mm; T with fine but regular and well developed axial lirae on early whorls, fading on later whorls; slightly erect upper keel; markedly beaded subsutural cord on later T whorls; body whorl with three peripheral spiral ribs and four basal spiral ribs; columellar lip with low basal fold or broadly folded; upper apertural sinus pronounced and thickened.</p> <p> <b>Distribution.</b> Apart from the studied material, this species is known only from the type locality in the Bohol Sea, Philippines, from 679–740 m water depth (Poppe <i>et al.</i> 2006).</p> <p> <b>Remarks.</b> The elongate shape, thin and regular axials, the beaded suprasutural ridge and the folded columellar lip distinguish this species from the two species treated above. The assignment of the present material to <i>S. elegantissima</i> is uncertain, because the outer lip is severely damaged in all specimens, making a complete comparison with the material described by Poppe <i>et al.</i> (2006) impossible. Furthermore the subsutural spiral ridge appears to be smooth to marginally knobby in the recent species, whereas it is distinctly beaded in the fossil material studied here. <i>Seguenzia praeceps</i> Marshall, 1991, <i>S. fulgida</i> Marshall, 1983 and <i>S. serrata</i> Marshall, 1983 are quite similar in shape, but their subsutural ridge is not as strongly crenulated as in the studied material.</p>Published as part of <i>Helwerda, Renate Ariane, Wesselingh, Frank Pieter & Williams, Suzanne T., 2014, On some Vetigastropoda (Mollusca, Gastropoda) from the Plio-Pleistocene of the Philippines with descriptions of three new species, pp. 101-135 in Zootaxa 3755 (2)</i> on page 110, DOI: 10.11646/zootaxa.3755.2.1, <a href="http://zenodo.org/record/250959">http://zenodo.org/record/250959</a>
SU‐E‐T‐35: A General Fill Factor Definition Serving to Characterise the MLC Misalignment Detection Capabilities of Two‐Dimensional Detector Arrays
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