161,216 research outputs found
Comparative analysis of the Arabidopsis and rice expressed sequence tag (EST) sets
No full textLarge numbers of expressed sequence tags (ESTs) have now been generated from a variety of model organisms. In plants, substantial collections of ESTs are available for Arabidopsis and rice, in each case representing significant proportions of the estimated total numbers of genes. Large-scale comparisons of Arabidopsis and rice sequences are especially interesting due to the fact that these two species are representatives of the two subclasses of the flowering plants (Dicotyledonae and Monocotyledonae, respectively). Here we present the results of systematic analysis of the Arabidopsis and rice EST sets. Non-redundant sets of sequences from Arabidopsis and rice were first separately derived and then combined so that gene families in common between the two species could be identified. Our results show that 58% of non-singleton ESTs are derived from genes in gene families common to the two species. These gene families constitute the basis of a core set of higher plant genes
A abordagem socioantropológica de Sophie Poirot-Delpech
No full textO objectivo deste artigo é apresentar o trabalho de Sophie Poirot-Delpech. Nas suas investigações, a autora tem contribuído para o desenvolvimento de uma tradição específica no âmbito da sociologia – a sócio-antropologia da técnica. Nesta abordagem, que tem beneficiado do contributo de outros autores (onde se destacam Alain Gras, Gérard Dubey, Caroline Moricot, Victor Scardigli), iremos procurar identificar pontos de convergência e de enriquecimento para a prática dos psicólogos do trabalho, nomeadamente, a ancoragem no real, a démarche participativa e a primazia do terreno. Pretendemos, assim, reflectir acerca da prática específica destes sociólogos, sobretudo a de Sophie Poirot-Delpech, dando particular atenção aos conceitos e métodos adoptados, no sentido de enfatizar as contribuições que estes representam para a investigação em psicologia do trabalho. Como principal contribuição salientamos o exercício de contextualização da actividade humana, da sua historicidade e da importância da sua (re)construção contínua como imperativos à sua compreensão
A abordagem socioantropológica de Sophie Poirot-Delpech
No full textO objectivo deste artigo é apresentar o trabalho de Sophie Poirot-Delpech. Nas suas investigações, a autora tem contribuído para o desenvolvimento de uma tradição específica no âmbito da sociologia – a sócio-antropologia da técnica. Nesta abordagem, que tem beneficiado do contributo de outros autores (onde se destacam Alain Gras, Gérard Dubey, Caroline Moricot, Victor Scardigli), iremos procurar identificar pontos de convergência e de enriquecimento para a prática dos psicólogos do trabalho, nomeadamente, a ancoragem no real, a démarche participativa e a primazia do terreno. Pretendemos, assim, reflectir acerca da prática específica destes sociólogos, sobretudo a de Sophie Poirot-Delpech, dando particular atenção aos conceitos e métodos adoptados, no sentido de enfatizar as contribuições que estes representam para a investigação em psicologia do trabalho. Como principal contribuição salientamos o exercício de contextualização da actividade humana, da sua historicidade e da importância da sua (re)construção contínua como imperativos à sua compreensão.El objetivo de este artículo es presentar el trabajo de Sophie Poirot-Delpech. En sus investigaciones, la autora ha contribuido para el desarrollo de una tradición específica en el ámbito de la sociología – la socio-antropología de la técnica. En este planteamiento, que ha beneficiado de la aportación de otros autores (donde se destacan Alain Gras, Gérard Dubey, Caroline Moricot, Victor Scardigli), intentaremos identificar puntos de convergencia y de enriquecimiento con la práctica de los psicólogos del trabajo, designadamente, el anclaje en lo real, la démarche participativa y la primacía del terreno. Pretendemos también dar particular atención a los conceptos y métodos adoptados, en el sentido de enfatizar las aportaciones que esta tradición científica representa para la investigación en psicología del trabajo. Se enfatiza particularmente el ejercicio de contextualización de la actividad humana, de su historicidad y de la importancia de su (re)construcción continua como imperativos a su comprensión.L´objectif de cet article est de présenter le travail de Sophie Poirot-Delpech. Dans ses recherches, l´auteur a contribué au développement d´une tradition particulière en sociologie la socio-anthropologie de la technique. On cherche à mettre en évidence ce qui, dans cette approche (qui a bénéficié des contributions d´autres auteurs, particulièrement Alain Gras, Gérard Dubey, Caroline Moricot, Victor Scardigli), présente des points de convergence avec la pratique des psychologues du travail, notamment pour ce qui concerne la centralité du réel, la démarche participative et l´importance du terrain. On accorde également une attention particulière aux contributions que les concepts et les méthodes utilisés au sein de cette tradition scientifique représentent pour la recherche en psychologie du travail. On met particulièrement en exergue l´exercice de la mise en contexte de l´activité humaine, de son historicité et de l´importance de sa (re)construction permanente, car ils sont des impératifs pour sa compréhension.The aim of this paper is to present the work of Sophie PoirotDelpech. Through her research, the author has contributed to the development of a specific tradition in the sociological domain – the social-anthropology of technique. In this approach (that has benefited from the contributions of other authors, particularly Alain Gras, Gérard Dubey, Caroline Moricot, Victor Scardigli) we try to identify convergence points with organizational psychologists´ practice, namely, the centrality of the real ; participative action ; and the importance of context. Particular attention is paid to the concepts and methods adopted, in order to emphasize the contributions that this tradition brings to the research on organizational psychology. Also accentuated is the exercise of contextualizing human activity, its historical character and the relevance of its continuous (re)construction as imperatives to the understanding of it
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Deduction in detective stories: Sherlock Holmes and Hercule Poirot
No full textBakalářská práce pojednává o dedukci v detektivní literatuře, tedy konkrétněji detektivů Sherlocka Holmese a Hercula Poirota. Práce se zaměřuje na dedukční postupy, které detektivové používají. Výsledkem práce bude zjištění, zda jsou dané postupy v souladu s dedukcí v moderní logice a metodologií věd.NeobhájenoThe thesis deals with deduction in detective literature, that is, more specifically, detective Sherlock Holmes and Hercule Poirot. The work focuses on their deductive processes. The result of the work will be detection whether are the procedures in accordance with the deduction in modern logic and methodology of science
Larry O. Spencer, Conference Author Presentation
No full textGen. Larry O. Spencer, USAF (Ret.), author of Dark Horse: A Journey from the Horseshoe to the Pentago
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Descriptive Text Mining in ambito medico: applicazione della metodologia POIROT
No full textPoiché la nostra conoscenza collettiva continua ad essere digitalizzata e memorizzata, diventa più difficile trovare e scoprire ciò che stiamo cercando.
Abbiamo bisogno di nuovi strumenti computazionali per aiutare a organizzare, rintracciare e comprendere queste vaste quantità di informazioni.
I modelli di linguaggio sono potenti strumenti che possono essere impiegati per estrarre conoscenza statisticamente significativa ed interpretabile tramite apprendimento non supervisionato, testuali o nel codice sorgente.
L’obiettivo di questa tesi è impiegare una metodologia
di descriptive text mining, denominata POIROT, per analizzare i rapporti medici del dataset Adverse Drug Reaction (ADE). Si vogliono stabilire delle
correlazioni significative che permettano di comprendere le ragioni per cui un determinato rapporto medico fornisca o meno informazioni relative a effetti collaterali dovuti all’assunzione di determinati farmaci
Natural and semisynthetic oxyprenylated aromatic compounds as stimulators or inhibitors of melanogenesis
No full textIt has been very recently shown how naturally occurring oxyprenylated coumarins are effective modulators of melanogenesis. In this short communication we wish to generalize the potentialities as skin tanning or whitening agents of a wider panel of natural and semisynthetic aromatic compounds, including coumarins, cinnamic and benzoic acids, cinnamaldehydes, benzaldehyde, and anthraquinone derivatives. A total number of 43 compounds have been tested assaying their capacity to inhibit or stimulate melanin biosynthesis in cultured murine Melan A cells. The wider number of chemicals herein under investigation allowed to depict a detailed structure-activity relationship, as the following: (a) benzoic acid derivatives are slightly pigmenting agent, for which the effect is more pronounced in compounds with longer O-side chains; (b) independently from the type of substitution, cinnamic acids are able to increase melanin biosynthesis, while benzaldehydes are able to decrease it; (c) coumarins with a 3,3-dimethylallyl or shorter skeletons as substituents in position 7 are tanning agents, while coumarins with farnesyloxy groups are whitening ones; (d) double oxyprenylation in position 6 and 7 and 3,3-dimethylallyl or geranyl skeletons have slight depigmenting capacities, while farnesyl skeletons tend to marginally increase the tanning effect; (e) the presence of electron withdrawing groups (acetyl, COOH, and -Cl) and geranyl or farnesyl oxyprenylated chains respectively in positions 3 and 7 of the coumarin nucleus lead to a whitening effect, and finally (f) oxyprenylated anthraquinones have only a weak depigmenting capacity
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