1,257 research outputs found
Pricing Rainfall Derivatives by Genetic Programming: A Case Study
No full textIn this contribution we consider a genetic programming approach to price rainfall derivatives and we test it on a case study based on data collected from a meteorological station in a city in the northeast region of Friuli Venezia Giulia (Italy), characterized by a fairly abundant rainfall
Teatro sociale in Italia: linee di sviluppo, ricorrenze metodologiche e istanze valutative
No full textil Capitolo intende offrire un quadro introduttivo del teatro sociale in quanto oggetto specifico della ricerca riportata nel presente Rapporto nonché pratica applicativa che si sta dimostrando particolarmente efficace nei contesti della salute
Successful Treatment of Refractory Seizures with Rufinamide in Children with Schizencephaly: Report of 3 Cases
No full textSchizencephaly is an uncommon malformation of cortical development. Patients with schizencephaly present with a broad range of severe neurologic symptoms including pharmacoresistant epilepsy. Rufinamide is a new antiepileptic drug approved for use as adjunctive therapy of seizures associated with Lennox-Gastaut syndrome and it is also effective for refractory partial seizures. We report 3 cases of pediatric patients aged 7.2, 8.1, and 10.1 years, respectively, with intractable epilepsy associated with bilateral open-lip schizencephaly and septo-optic dysplasia. The follow-up ranged from 3.8 to 4.1 years. In our patients, the introduction of rufinamide as adjunctive drug led to a dramatic decline in the number of seizures and an improvement in EEG epileptic activity without side effects. Rufinamide seems to be efficacious and safe in patients with epileptic encephalopathies associated with pharmacoresistant epilepsy; further and larger clinical reports and controlled studies could confirm the usefulness of this anticonvulsant drug
La propensione all’export: un’analisi a livello di impresa in Veneto
No full textIn una fase di crisi economica, in cui la domanda domestica si contrae, un ruolo
importante per la sopravvivenza delle aziende può essere giocato dalla domanda
internazionale. Essa appare come un sostegno per le aziende esportatrici abituali e
un'opportunità per le dinamiche di vendita delle aziende che ancora non operano
sui mercati esteri o il cui coinvolgimento è molto limitato.
Il presente contributo cerca di verificare questa affermazione con riferimento
alle imprese manifatturiere venete, considerando i singoli comportamenti aziendali,
piuttosto che le appartenenze settoriali, come suggerito dalla più recente letteratura
economica sull’internazionalizzazione (Melitz, 2003).
L’analisi a livello di singola azienda è stata possibile grazie all’integrazione di
due fonti distinte: l’Indagine Congiunturale Unioncamere del Veneto (dati
trimestrali dal 2006 al 2011) e i micro-dati sul commercio estero (fonte Istat)
relativi alle esportazioni a livello d’impresa (dati annuali dal 2009 al 2010)
Giulia Veronica Varisco
No full textThe headword explains the biography and the contribution of the author Giulia Varisco to the children's literatur
EVALUATION OF ENVIRONMENTAL FACTORS ON CANINE REPRODUCTION AND FERTILITY: INNOVATIVE STRATEGIES
No full textFertility assessment is challenging both in human and canine species because it is defined by a combination of numerous genetic and environmental factors. In recent decades, a decline in humans fertility occurred and was related to environmental pollutants, such as endocrine disruptor chemicals (EDCs), that increased dramatically as result of technological development. Living close to their owners, dogs are exposed to similar risks whose impact on their reproduction is still unclear. Many widespread compounds may interfere with canine reproductive health from embryonic development up to conception.
Since environmental hazards in dogs are poorly understood, this PhD thesis comprises four studies devoted to exploring their consequences on canine reproduction and fertility.
The first two projects were centered on the exposure of breeding dogs to cigarette smoke. Cotinine was applied as marker of nicotine intake in male dogs and pregnant bitches belonging to smoking and non-smoking owners. Significant differences were highlighted between exposed and non-exposed dogs, however measurable levels of this metabolite were detected in serum, semen, hair, and amniotic fluid of all enrolled patients. Despite nicotine metabolites increase seminal oxidative stress, in our caseload the level of total antioxidant capacity (TAC) in ejaculate didn’t correlate with male dogs’ exposure to tobacco smoke. Albeit the practical effects of passive smoke should be investigated on a larger sample size, results obtained demonstrated a non-negligible exposure that could interfere with dogs’ reproductive performance.
Apart from tobacco smoke consequences, within other two studies we focused on cryptorchidism. Through the application of immunohistochemical techniques and miRNomics, we found precancerous lesions and molecular dysregulation in both retained and scrotal gonads of affected patients. Interesting implications have emerged from this outcome especially concerning testicular neoplastic predisposition and the appropriate therapeutic approach in unilateral cryptorchids. In addition, molecular pathways suggested an abnormal expression of estrogen receptors that, as assumed in humans, may justify a greater sensitivity to EDCs even in cryptorchid dogs.
Regardless some limitations, the overall outcomes of the present doctoral dissertation pointed out the environmental role on canine reproduction. Although pollutants’ effects can’t be completely eliminated, greater awareness should be placed on common bad habits like cigarette smoke which could impair fertility potential even in “man’s best friend”
Ytterbium Disilicate/Monosilicate Multilayer Environmental Barrier Coatings: Influence of Atmospheric Plasma Spray Parameters on Composition and Microstructure
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Open AccessArticle
Ytterbium Disilicate/Monosilicate Multilayer Environmental Barrier Coatings: Influence of Atmospheric Plasma Spray Parameters on Composition and Microstructure
by Giulia Di Iorio,Laura Paglia *ORCID,Giulia PedrizzettiORCID,Virgilio GenovaORCID,Francesco MarraORCID,Cecilia BartuliORCID andGiovanni PulciORCID
INSTM Reference Laboratory for Materials and Surface Engineering, Sapienza University of Rome, Eudossiana 18, 00184 Rome, Italy
*
Author to whom correspondence should be addressed.
Coatings 2023, 13(9), 1602; https://doi.org/10.3390/coatings13091602
Original submission received: 10 August 2023 / Revised: 31 August 2023 / Accepted: 11 September 2023 / Published: 13 September 2023
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Abstract
SiC/SiC ceramic matrix composites (SiCf/SiC CMCs) are regarded as the new materials for the hot-section components of aircraft gas turbine engines, since they have one-third of the density of metallic superalloys, a higher temperature capability, good mechanical strength, and excellent thermal shock resistance. However, high-temperature water-vapor-rich combustion gases can induce severe surface recession phenomena in SiC/SiC leading to component failure. For this reason, it is necessary to design protective coatings, i.e., environmental barrier coatings (EBCs), able to protect the SiC/SiC surface in combustion environments. In the present work, ytterbium monosilicate (Yb2SiO5), stable when exposed to water vapor at high temperatures, and ytterbium disilicate (Yb2Si2O7), characterized by a thermal expansion coefficient closer to that of the substrate, were selected for a multilayer EBC system. EBCs were processed using the atmospheric plasma spray (APS) technique. A set of deposition parameters were tested, varying the power of the torch, and the composition and microstructure of the deposited coatings were studied in terms of porosity, crack density, and post-deposition phase retention by performing SEM, EDS, and XRD analysis. The results allow for the definition of the influence of deposition parameters on the final properties of multilayer EBC coatings
Correction to: Safety and Psychological Outcomes of Tandem t:Slim X2 Insulin Pump with Control-IQ Technology in Children, Adolescents, and Young Adults with Type 1 Diabetes: A Systematic Review
No full textThe second author name was incorrectly published as Giula Maria Smylie. The correct name is Giulia Marie Smylie. The original article has been corrected
Promozione della salute e del benessere tramite laboratori di teatro sociale: un’esperienza di ricerca partecipata
No full textIl Rapporto descrive un’esperienza di ricerca partecipata su laboratori di teatro sociale e promozione della salute e del benessere maturata nell’ambito dell’Accordo Quadro dal titolo “Sinergie tra epidemiologia ambientale e sociale e discipline artistiche, in particolare il teatro sociale, nella promozione della salute”, stipulato tra l’Istituto Superiore di Sanità e l’Università Cattolica del Sacro Cuore di Milano. Quanto documentato è frutto di attività che hanno visto lacollaborazione di ricercatrici e ricercatori nei settori
dell’epidemiologia, della psicologia, delle humanities, e operatrici e operatori di teatro sociale. La prima parte del Rapporto descrive il razionale e gli aspetti teorici che sono alla base della ricerca, la seconda riporta le attività di ricerca realizzate e si conclude con la discussione critica dell’esperienza al fine di identificarne le lessons learned
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