364 research outputs found
Implementation, feasibility, and acceptability of 99DOTS-based supervision of treatment for drug-susceptible TB in Uganda.
No full text99DOTS is a low-cost digital adherence technology that allows people with tuberculosis (TB) to self-report treatment adherence. There are limited data on its implementation, feasibility, and acceptability from sub-Saharan Africa. We conducted a longitudinal analysis and cross-sectional surveys nested within a stepped-wedge randomized trial at 18 health facilities in Uganda between December 2018 and January 2020. The longitudinal analysis assessed implementation of key components of a 99DOTS-based intervention, including self-reporting of TB medication adherence via toll-free phone calls, automated text message reminders and support actions by health workers monitoring adherence data. Cross-sectional surveys administered to a subset of people with TB and health workers assessed 99DOTS feasibility and acceptability. Composite scores for capability, opportunity, and motivation to use 99DOTS were estimated as mean Likert scale responses. Among 462 people with pulmonary TB enrolled on 99DOTS, median adherence was 58.4% (inter-quartile range [IQR] 38.7-75.6) as confirmed by self-reporting dosing via phone calls and 99.4% (IQR 96.4-100) when also including doses confirmed by health workers. Phone call-confirmed adherence declined over the treatment period and was lower among people with HIV (median 50.6% vs. 63.7%, p3 consecutive doses. Surveys were completed by 83 people with TB and 22 health workers. Composite scores for capability, opportunity, and motivation were high; among people with TB, composite scores did not differ by gender or HIV status. Barriers to using 99DOTS included technical issues (phone access, charging, and network connection) and concerns regarding disclosure. 99DOTS was feasible to implement and highly acceptable to people with TB and their health workers. National TB Programs should offer 99DOTS as an option for TB treatment supervision
Book Ends & Odd Books : Publications Refuting Conventional Form from the Banff Centre Library Collection
No full textMathur explains how he "unselected" nearly 200 works for this exhibition of unconventional publications by international artists and authors, recognizing the influence of Ulises Carrion's article "The New Art of Making Books." The author reflects upon the roles of language and poetics, the distinction between book and text, and how politics and power affect the making and reception of these works. 2 bibl. ref
Book review: paper tiger: law, bureaucracy and the developmental state in Himalayan India by Nayanika Mathur
No full textFollowing eighteen months of intensive fieldwork, in Paper Tiger: Law, Bureaucracy and the Developmental State in Himalayan India author Nayanika Mathur details the everyday absurdities of bureaucracy in the Himalayan borderlands, showing the frequent gulf between ‘real life’ and the abstract workings of the law. Elisabetta Iob highly recommends this accessible, witty and vividly written book as an outstanding and essential example of ethnographic research
FINANCING COMMUNITY FACILITIES: A CASE STUDY OF THE PARKS AND RECREATIONAL GENERAL OBLIGATION BOND MEASURE OF SAN JOSE, CALIFORNIA
No full textThis study of the City of San Jose’s Parks and Recreation General Obligation (GO) Bond Measure seeks to identify the politics-, management-, and planning-related lessons learned by the City as it developed its community facilities using the GO bonds proceeds. The study finds that these lessons include: be conservative in what you promise the residents; be prepared for changes in economic environment by identifying supplementary funding sources should the primary source not yield adequate funds; make sure that the jurisdiction is organizationally capable of handling the increased workload; and prepare detailed project plans prior to the bond issuance.Community Infrastructure and Services; Municipal Bonds; Public Finance
An Analytical Criterion for Centrifugal Instability in Non-Axisymmetric Vortices
No full textNon-axisymmetric vortices are ubiquitous in nature; examples include polar vortices in planets, the giant red spot in Jupiter, tornadoes and cyclones on Earth, mesoscale eddies in the ocean. Turbulent flows are furthermore known to be dominated by small- and large-scale vortex structures. Owing to the wide range of applications, knowledge of conditions under which a given vortex becomes unstable is beneficial. Here, the centrifugal instability of two-dimensional, non-axisymmetric vortices in the presence of an axial flow and a background rotation is studied using the local stability approach. The local stability approach, based on geometric optics and similar in formulation to the rapid distortion theory \cite{bib:godeferd2001}, considers the evolution of shortwavelength perturbations along streamlines in the base flow. This approach, developed by Lifschitz Hameiri \cite{bib:lifschitz1991}, is particularly useful for base flows for which a global stability analysis is computationally expensive. A sufficient criterion for centrifugal instability in an axisymmetric vortex with and is first derived by analytically solving the local stability equations for wave vectors that are periodic upon evolution around a closed streamline. This criterion is then heuristically extended to non-axisymmetric vortices and written in terms of integral quantities on a streamline. The criterion is then shown to be accurate in describing centrifugal instability over a reasonably large range of parameters that specify Stuart vortices and Taylor-Green vortices
Making peace with the earth: beyond resource, land and food wars - By Vandana Shiva
No full text\u27When we think of wars in our times, our minds automatically turn to Iraq and Afghanistan, but the bigger war is the on-going war against the earth\u27. Thus begins Vandana Shiva\u27s alarming exposé of what she believes is an all-out capitalistic assault on Mother Earth. Here, \u27[t]he global corporate economy based on the idea of limitless growth\u27 is presented as a \u27a permanent war economy against the planet and people\u27—comprising a combination of \u27land-grab,\u27 \u27water wars,\u27 \u27climate wars,\u27 \u27forest wars,\u27 and \u27seed wars.\u2
An Interactive Dialogue for the Creation, Maintenance and Querying of a Data Base Representative of the Anatomy of an Administrative System
No full textTitle: An Interactive Dialogue for the Creation, Maintenance and Querying of a Data Base Representative of the Anatomy of an Administrative System, Author: Pratima Mathur, Location: ThodeThe logical structure of a database is given, and is
representative of the anatomy of an administrative system,
and of the personnel organization by which it is operated.
This project will adopt an appropriate host computer,
terminal, and physical representation of the database, for
the main purpose of developing a user-terminal dialogue by
which the database can be created and maintained. The
dialogue should be as easy and flexible to use by an audit
analyst as is possible, while at the same time imposing a
systematic and disciplined approach to the task.ThesisMaster of Science (MS
Uncovering a novel role for FXR-SHP axis in liver physiology, diseases and beyond
No full textLiver performs a multitude of functions ranging from detoxification, metabolism and digestion. To execute these tasks, one of the mechanisms that the liver utilizes is nuclear receptor signaling, which in turn can transcriptionally regulate gene networks. My doctoral thesis focuses on studying the role of two nuclear receptors, FXR and SHP in maintaining liver function. Farnesoid X Receptor (FXR) and Small Heterodimer Partner (SHP) are well-known regulators of glucose, fat and bile acid homeostasis. Here, I uncover novel roles for FXR-SHP axis not only in the liver but also in extrahepatic organs, like heart. In Chapter 2, I discuss how hepatic loss of FXR and SHP results in increased glycosylation of liver proteins and structural defects in Golgi apparatus, and ultimately liver cancer. Chapter 3 focuses on comprehending how FXR-SHP ablation results in increased drug metabolic capacity of the liver. Finally, chapter 4 discusses how liver dysfunction, caused by loss of FXR and SHP, can induce metabolic and functional defects in heart. Taken together, these projects will help understand some of the FXR and SHP transcriptional networks under different physiological and pathological contexts and may open avenues for pharmacological manipulation to treat various diseases.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-08-01The student, Bhoomika Mathur, accepted the attached license on 2019-07-04 at 01:18.The student, Bhoomika Mathur, submitted this Dissertation for approval on 2019-07-04 at 01:31.This Dissertation was approved for publication on 2019-07-09 at 15:41.DSpace SAF Submission Ingestion Package generated from Vireo submission #14170 on 2019-11-26 at 13:04:27Made available in DSpace on 2019-11-26T20:49:21Z (GMT). No. of bitstreams: 3
MATHUR-DISSERTATION-2019.pdf: 4474420 bytes, checksum: 0728cd0303f8ab823c20e40908832fc6 (MD5)
LICENSE.txt: 4212 bytes, checksum: c236fb3ffdc64338bde4c118696e9cf1 (MD5)
RightsLink Printable License_Copyright letter_Bhoomika.pdf: 202690 bytes, checksum: 3eb71388cf9fd446d7a972db6b8c76f4 (MD5)
Previous issue date: 2019-07-09Embargo set by: Seth Robbins for item 112930
Lift date: 2021-11-26T20:49:41Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 112930 on 2021-11-27T10:15:09Z
Get Ready for the Next Generation of AI Quantum Technologies
No full textA new form of artificial intelligence is on the horizon that will transform healthcare and other industries in unimaginable ways. The purpose of this book chapter is to foreshadow the next generation of quantum technologies that are ideally suited to healthcare artificial intelligence applications. Early adopters, innovators, and other thought leaders in healthcare can champion actions today (regarding technology, processes, and people) to guide their organizations to a quantum technologies ecosystem to optimize caregiving
- …
