1,720,963 research outputs found

    Spurious hyperglycaemia impairs automated leucocyte counting. A pilot study with two different haematological analysers

    No full text
    Spurious hyperglycaemia impairs automated leucocyte counting. A pilot study with two different haematological analyser

    Harmonization of red blood cell distribution width (RDW): an attainable target?

    No full text
    Background: Although red blood cell distribution width (RDW), an indirect measure of anisocytosis, is receiving increasing interest as a diagnostic and prognostic factor in a vast array of human disorders, harmonization of this measure remains an unmet target. In the current study, we explored whether a novel statistic approach may help achieving a major degree of harmonization for this measure. Methods: The first part of the study was based on measurement of six reference samples with four different hematologic analyzers (Siemens Advia 2120, Sysmex XE5000, Mindray BC6800, Abbott Sapphire). A polynomial curve was constructed by interpolating the values obtained with the four analyzers. The validation study was based on measurement of 126 inpatient samples analyzed with the same four instruments. The raw values and those recalculated according to the coefficients of the polynomial curves were finally compared. Results: The distribution of raw values obtained with the four hematological analyzers was always significantly different, but in no case did the differences remain significant after RDW values were recalculated with instrument-specific polynomial curves. The man bias of RDW values obtained with the different hematological analyzers could be considerably reduced after recalculation of values. In all cases except one the slopes and the intercepts of the Deming’s fits were significantly improved after recalculation. Conclusions: The results of this pilot study show that a major degree of harmonization of RDW values measured by different hematological analyzers may be simply achieved by recalculating values according to instrument-specific polynomial curves

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    The role of neutrophil gelatinase-associated lipocalin (NGAL) in cerebrospinal fluids for screening of acute bacterial meningitis

    No full text
    Acute bacterial meningitis is a rare but extremely severe disease. The aim of this study was to investigate whether neutrophil gelatinase-associated lipocalin (NGAL) is present and measurable in cerebrospinal fluid (CSF) and if its assessment may be useful for identifying patients with bacterial meningitis

    Variations on the Author

    Full text link
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

    Full text link
    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

    Full text link
    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

    No full text
    Nao informado
    corecore