1,721,021 research outputs found

    Clinical predictors of encephalitis in UK adults-A multi-centre prospective observational cohort study.

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    ObjectivesEncephalitis, brain inflammation and swelling, most often caused by an infection or the body's immune defences, can have devastating consequences, especially if diagnosed late. We looked for clinical predictors of different types of encephalitis to help clinicians consider earlier treatment.MethodsWe conducted a multicentre prospective observational cohort study (ENCEPH-UK) of adults (> 16 years) with suspected encephalitis at 31 UK hospitals. We evaluated clinical features and investigated for infectious and autoimmune causes.Results341 patients were enrolled between December 2012 and December 2015 and followed up for 12 months. 233 had encephalitis, of whom 65 (28%) had HSV, 38 (16%) had confirmed or probable autoimmune encephalitis, and 87 (37%) had no cause found. The median time from admission to 1st dose of aciclovir for those with HSV was 14 hours (IQR 5-50); time to 1st dose of immunosuppressant for the autoimmune group was 125 hours (IQR 45-250). Compared to non-HSV encephalitis, patients with HSV more often had fever, lower serum sodium and lacked a rash. Those with probable or confirmed autoimmune encephalitis were more likely to be female, have abnormal movements, normal serum sodium levels and a cerebrospinal fluid white cell count ConclusionsInitiation of treatment for autoimmune encephalitis is delayed considerably compared with HSV encephalitis. Clinical features can help identify patients with autoimmune disease and could be used to initiate earlier presumptive therapy

    CLINICAL PATHWAY DALAM PELAYANAN STROKE AKUT: APAKAH PATHWAY MEMPERBAIKI PROSES PELAYANAN?

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    Background: The stroke care pathway is a simple resourcethat provides the user with a summary of the key aspects ofcare that should be considered for people with stroke at anystage in their care. There is very limited study about the use ofclinical pathway in Indonesia.Aim: This study described the process of developing clinicalcare pathway and the trial of pathway for 50 patients withacute stroke.Method: The method of this study is after-before analysis.We compare the process and outcome of non haemorrhagicstroke patients before and after the pilot implementation of thepathway. The data was obtained randomly from the medicalrecord of stroke patients. The data was analyzed descriptively.Result: The data from 50 non haemorrhagic stroke patientsafter the pilot implementation of clinical pathway were comparedwith the data from previous year. The analysis showed thatthere are improvement in the tracing for stroke risk factors,swallowing assessment, nutritional consultation, and functionalstatus measurement after the pathway implementation. Thereare not significant reductions on the average length of stayand mortality rate between the two periods.Conclusion: Our study showed that clinical pathway isimproving the indicator of stroke care services. The furtherstudy for evaluating the effectiveness of stroke care pathwayin longer period is warranted.Keywords: clinical pathway, stroke, process of care, outcom

    Awas Stroke : Pengertian, Gejala, Tindakan, Perawatan & Pencegahan

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    Buku "AWAS STROKE" yang ditulis oleh dr. Rizaldy Pinzon memberikan informasi mengenai pengertian, gejala, tindakan, perawatan, dan pencegahan terhadap stroke. Dalam buku ini, penulis menjelaskan bahwa stroke adalah defisit fungsi sistem saraf yang terjadi mendadak akibat gangguan peredaran darah di otak. Pembaca akan memahami jenis-jenis stroke, termasuk stroke sumbatan (stroke iskemik) dan stroke perdarahan.Dr. Rizaldy Pinzon mengulas tentang gejala-gejala stroke dan langkah tindakan yang harus diambil jika seseorang mengalami serangan stroke. Buku ini juga memberikan informasi tentang perawatan dan langkah pencegahan untuk mengurangi risiko terjadinya stroke.68 p, ill, 18 c

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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