1,721,014 research outputs found
Distribuzione e variabilità del genereArbutusL.: analisi sistematica e morfologia integrata diArbutus unedoL. in Sardegna
In this study, systematic ofArbutuswas examined in literature, by investigating the number, distribution and diagnostic characters of its species. Then, the place names in Sardinian language meaning “Strawberry Tree” were identified, to make a distribution map of these localities in Sardinia. Finally, morphological variability of four populations of Strawberry Tree (Arbutus unedoL.) growing in four areas of Sardinia, with different geolithological conditions, was assessed. Morphometric analysis, based on eleven morphological traits, was performed on three leaves and three fruits per plant, sampled from thirty plants per population. Standard biometric methods were used for leaf and fruit physiognomy, and a geometric morphometric approach used for leaf conformation. Statistical multivariate analysis showed significant differences between populations (p<0.05) and high discrimination percentages. The most important discriminating traits were: petiole length, leaf width, ratio between distal part and total lamina length, fruit length, fruit width, and ratio between fruit length/fruit width. Climatic differences among the four areas and significant correlations between morphological traits and ecological parameters were found. In conclusion, environment plays an important role in the observed variations, so populations can be considered different. Based on the literature and fieldwork carried out, new forms and a variety ofArbutus unedowere found for the first time in Italy
Contributo allo studio e valorizzazione del pane di ghiande
La presente ricerca nasce dalla consapevolezza del valore delle tradizioni locali, la cui conservazione rappresenta motivo fondamentale di arricchimento conoscitivo, culturale, storico e sociale. Il lavoro mira al recupero dell'antico legame uomo-natura con l'intento di tutelare, valorizzare e riscoprire un'antica tradizione culinaria ormai caduta in disuso: quella della panificazione delle ghiande
Epithelial-stromal interaction in the pathogenesis of colorectal cancer
Colorectal cancer (CRC) is not a homogenous disease. Recent molecular classification of established tumours based on gene expression and (epi)genetic mutation burden, has revealed considerable disease heterogeneity. The relative importance of the epithelial and stromal tissue compartments varies between different tumour subtypes and this contributes to the observed clinical and molecular heterogeneity of CRC.
The AIM of this study was to explore the role of the stroma in different precancerous pathologies (polyps) and in CRC.
Stromal gene expression varies considerably between the different polyp subtypes (SSA and TVA) with a comparatively greater number of differentially expressed genes in serrated lesion stroma, suggesting the hypothesis that SSA lesions, usually initiated by BRAF mutations and methylation, require the recruitment of pro-tumorigenic stroma to enable lesion progression. In contrast, TVA are initiated by epithelial mutations that disrupt Wnt signaling (such as APC) and this is sufficient to drive tumourigenesis, irrespective of stromal influences.
Moreover, transwell tissue culture 3D techniques and animal models revealed that fibroblasts support the cross species growth of mouse epithelial organoids and abrogate the normal media requirement for Noggin and EGF. Interestingly, mouse epithelium grown in this co culture system develop as spheroids rather than the branching organoids seen with media morphogen supplementation, indicating a phenotype modulating effect of the fibroblasts.
Preliminary results revealed that fibroblasts have effects on cell proliferation and cell cycle regulation by upregulation of genes involved with cell cycle progression, DNA synthesis/repair, protein translation, vesicles mediated transport and lipid metabolism.
Primary stromal cell cultures isolated from adenoma and colon cancer (CMS2 and CMS4) might in part represent the corresponding cancer microenvironment, thus providing a useful complement to the current cellular biochemistry and therapeutic research in CRC
Percezione visiva dei pannelli a messaggio variabile: stima di un modello di previsione dei tempi di lettura
Clavibacter michiganensisandPseudomonas corrugateinfections on tomato plants grown in Sardinia greenhouses
Since autumn 2012, severe outbreaks ofClavibacter michiganensissubsp.michiganensis (Cmm)with losses up to 80% have been occurring in fifteen tomato greenhouse in south Sardinia. Varieties affected were: F1 hybrid Bubu, Camonium, DRW 7723, Terminetor and Flortyl grafted on Maxifort
Product development kpis: A case study analysis in food and fashion companies
Two of the main industries that are currently paying huge attention to Product Development (PD) are Food & Fashion (F&F). Even if the remaining supply chain processes (production, distribution, sales) are managed in different ways and dissimilar outsourcing policies are adopted, PD is the most valuable process that both the industries are emphasizing. In the Italian context, F&F also represent two of the three excellences of the Made in Italy (Furniture is the third element), also known as "3F". Therefore, this research constitutes a progress of a previous work, which has examined critical success factors, PD features and PLM functionalities in the two sectors. The aim of this study is to analyse how to control, to monitor and to enhance PD through Key Performance Indicators (KPIs) in F&F companies. From the methodological point of view, case study is adopted as a research strategy, designing two questionnaires with a common structure in order to obtain the required information. Indeed, different companies, belonging to the sectors of interest, have been selected and interviewed. As a result, KPIs are identified and classified. Moreover, a comparison between the previously listed metrics is performed and the drivers affecting similarities and differences are highlighted. This research helps to fill the literature gap, given the few contributions related to product development in the F&F supply chains. It also represents a valuable insight for practitioners who are trying to improve business processes and to increase the control over product development
Nuovi fitofagi degli eucalipti e impatto sulla produzione mellifera in Sardegna
Gli eucalipti sono un genere di piante sempreverdi originarie dell’Oceania e appartenenti alla famiglia delleMyrtacee. Per il loro elevato potenziale nettarifero e pollinifero, costituiscono una delle più importanti risorse di interesse apistico in ambito mediterraneo e a livello mondiale. In particolare, la specieE. camaldulensis, introdotta in Sardegna agli inizi del secolo scorso, caratterizza ormai alcuni paesaggi agricoli delle zone costiere e di pianura, dove è stato utilizzato originariamente come frangivento e per le opere di bonifica
idraulica delle zone paludose. La superficie complessiva attualmente, non considerando i filari e gli impianti inferiori all’ettaro, ammonta a circa 22.000 ha. A partire dal 1969 sono stati segnalati i primi fitofagi (Phoracanthaspp. (Coleoptera: Cerambycidae)) senza
particolari ripercussioni negative. In anni recenti (2010-2015) il quadro fitosanitario si è notevolmente aggravato con l’introduzione e la diffusione dei rincotiGlycaspis brimblecombeieThaumastocoris peregrinus. Nel corso del 2013-2015, le popolazioni di
tali fitomizi sono state monitorate, soprattutto in seguito all’allarme lanciato dagli apicoltori per il mancato o ridotto ottenimento del miele di eucalipto, che rappresenta circa il 50% dell’intera produzione regionale. L’indagine è stata condotta su tutto il territorio regionale, in 12 siti di campionamento
CHARACTERIZATION OF PSEUDOMONAS POPULATIONS ISOLATED FROM HAZELNUT (CORYLUS AVELLANA L.) TREES IN SARDINIA (ITALY)
Studies on hazelnut in Sardinia showed the presence of different bacterial populations (Xanthomonas arboricola pv. corylina, Pseudomonas syringae pv. syringae and P. syringae pv. coryli) causal gents of dieback. In field surveys carried out in autumn and spring 2014-2015 in the central part of Sardinia (Barbagia di Belvi), on hazelnut cultivations, were observed plants showing atypical symptoms characterized by the presence of necrosis along leaf veins and young shoots and atypical canker lesions, with or without hypertrophies, on one/two years old branches. Twenty-five isolates obtained from tissues with symptoms were characterized, four, on sucrose nutrient agar, were levan positive, instead the others twenty-one were negative. All isolates induced a hypersensitivity reaction on tobacco leaves, were pathogens, with different degrees, on hazelnut plantlets and showed a different pathogenic reaction on tomato and bean seedlings. The isolates were assessed for serological slide agglutination test using an antiserum from Pseudomonas syringae van Hall: 20 of them showed a positive reaction. Metabolic profile performed by Biolog GEN III microplates showed that all the twenty- five isolates belong to Pseudomonas genus. In particular: three of them were P. caricapapayae, two P. fluorescens, five P. syringae, five P. syringae pv. tabaci, ten P. syringae pv. anthirrini. These latter were characterized to grow on lincomycin, vancomycin, rifamycin sv, quinic acid, 1% sodium lactate, tetrazolium violet, tetrazolium blue, niaproof 4, potassium tellurite and pH 6. Molecular characterization of these bacteria as well as further tests to determine their pathogenic role are currently underway
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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