3,710 research outputs found
FP_Supplemental_revised_Tables_4.2019 – Supplemental material for Tumour incidence in Fabry disease: A cross-sectional study
No full textSupplemental material, FP_Supplemental_revised_Tables_4.2019 for Tumour incidence in Fabry disease: A cross-sectional study by Federica Rossi, Sara Auricchio, Agnese Binaggia, Vincenzo L’imperio, Fabio Pagni and Federico Pieruzzi in Journal of Onco-Nephrology</p
Statistical_method_Fabry_Cancer1 – Supplemental material for Tumour incidence in Fabry disease: A cross-sectional study
No full textSupplemental material, Statistical_method_Fabry_Cancer1 for Tumour incidence in Fabry disease: A cross-sectional study by Federica Rossi, Sara Auricchio, Agnese Binaggia, Vincenzo L’imperio, Fabio Pagni and Federico Pieruzzi in Journal of Onco-Nephrology</p
Milano consolato nell' elettione a questo arciuescouado, e promotione alla sagra porpora dell' eminentissimo Federico Visconti : colla sua solennissima entrata seguita a' 11. genaro 1682 e fontioni antecedenti /
No full textFrontispiece coat of arms of Milan, engraved by Federico Agnelli.Signatures: pi⁴ A-G⁴ H⁴(-H4).Mode of access: Internet.Binding: limp vellum. Author & title written on spine
Correction to: Outcomes on safety and efficacy of left atrial appendage occlusion in end stage renal disease patients undergoing dialysis (Journal of Nephrology, (2021), 34, 1, (63-73), 10.1007/s40620-020-00774-5)
No full textThe article Outcomes on safety and efficacy of left atrial appendage occlusion in end stage renal disease patients undergoing dialysis, written by Simonetta Genovesi, Luca Porcu, Giorgio Slaviero, Gavino Casu, Silvio Bertoli, Antonio Sagone, Monique Buskermolen, Federico Pieruzzi, Giovanni Rovaris, Alberto Montoli, Jacopo Oreglia, Emanuela Piccaluga, Giulio Molon, Mario Gaggiotti, Federica Ettori, Achille Gaspardone, Roberto Palumbo, Francesca Viazzi, Marco Breschi, Maurizio Gallieni, Gina Contaldo, Giuseppe D’Angelo, Pierluigi Merella, Fabio Galli, Paola Rebora, Mariagrazia Valsecchi, and Patrizio Mazzone, was originally published electronically on the publisher’s internet portal on 6 June 2020 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on 10 July 2020 to © The Author(s) 2020 and this article is licensed under a Creative Commons Attribution 4.0 International License (http://creat iveco mmons .org/licen ses/ by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The original article has been updated
»It contained harbours that pleased me like sonnets«. Kleine Poetik der diegetischen Karte
No full textIn this article, Federico Italiano explores the relationship between literature and cartography. Beginning with Stevenson’s Treasure Island, the author frames the topic through a general theoretical lens on the spatial dimension of literary texts. He then focuses on a specific phenomenon of literary "carticity"—the diegetic presence of the map, that is, the map as an integral element of the narrative structure. Among others, Italiano examines the works of Houellebecq and Cormac McCarthy
The GALA project: practical recommendations for the use of migalastat in clinical practice on the basis of a structured survey among Italian experts
No full textBackground Oral migalastat has recently been approved for the treatment of Anderson-Fabry disease (FD) in patients aged >= 16 years with amenable mutations on the basis of two phase III trials, FACETS and ATTRACT. However, with the introduction of migalastat into clinical practice, it is important to correctly identify the patients who may gain the most benefits from this therapy. Due to the relatively recent availability of migalastat, its role in clinical practice still has to be included in guidelines or recommendations. On these bases, a multidisciplinary group of Italian Experts in the treatment of FD has run the GALA project, with the aim to collect the opinions of expert physicians and to propose some starting points for an experience-based use of migalastat. Results Overall, although studies and data from longer-term follow-up with migalastat are still emerging, available evidence is consistent in showing that this molecule does represent a suitable therapy for the treatment of FD, in patients aged >= 16 years and with amenable mutations. The use of migalastat as an oral option appears to be overall safe, and experience thus far indicates potential for improving quality of life, controlling GI symptoms, stabilizing renal function and reducing cardiac hypertrophy. Conclusion Migalastat can be considered either as a first-line therapy - given its efficacy, extensive tissue penetration, convenient oral regimen, and the current limited therapeutic options available - or in patients on enzyme-replacement therapy (ERT) who experience side effects, with poor compliance to chronic i.v. therapy, or with clinical evidence of progression of the disease
Portrait of the Author in (Him/Her)self
No full textA fragment of a philosophical essay by Jean-Luc Nancy and Federico Ferrari titled Iconographie dell’auteur (Paris, 2005), published for the first time in Polish, that addresses the problem of a relationship between the image of the author and his/her work
Aneddoti e ricette a corte di Federico II nel XXI secolo : il buon cibo e il buon bere nel più antico Ateneo pubblico al mondo
No full text[Italiano]: Questo volume rappresenta la finalizzazione di una iniziativa nata, condivisa ed interamente realizzata all'interno del gruppo social dei "Prof in cucina e in Cantina", che ha inteso raccogliere ricette e descrizioni aneddotiche di singoli Autori, appartenenti ai ruoli del personale docente e tecnico-amministrativo-bibliotecario dell'Ateneo federiciano, il più antico Ateneo pubblico al mondo. Aneddoti e ricette forniscono spaccati di vita quotidiana e ricostruzioni di eventi che hanno accompagnato gli Autori nei diversi percorsi formativi, sociali e lavorativi, e che non escludono riferimenti al recente periodo emergenziale della pandemia COVID-19. Ad introdurre il Volume è un menù federiciano, con una proposta di 3 pietanze che attualizzano ricette ed abitubini alimentari dell'epoca, e che hanno come riferimento il Liber de coquina, edito a corte di Federico II. Gli 8 Capitoli del volume raggruppano ricette e aneddoti per categorie, e ciascuno di essi è poi preceduto da un breve inserto con ulteriori riferimenti storici all'alimentazione a Corte di Federico II. Così, atmosfere vecchie e nuove, accompagnate dal sentore di aromi e da suggestioni ispirate al vissuto di ciascun Autore, si fondono per offrire a Lettrici e Lettori frammenti di quotidianità vissuti oggi a corte di Federico II, nel XXI secolo./[English]: The Volume represents the endpoint of a recent initiative, which was conceived, shared and fully realized within the social group of the "Prof in Cucina e in Cantina". Here, the several Authors, represented by the teaching and the technical/administrative/librarian staff of the Federico II University in Naples, the oldest public University in the world, propose recipes and anecdotal descriptions of their educational, social and work-related paths, including some episodes from the recent COVID-19 pandemic. A menu inspired to Frederick II introduces the book, with 3 recipes inspired to the Liber de coquina, a cooking manual compiled at the Emperor's court. Each of the following 8 thematic chapters of the book is also anticipated by a brief insert reporting historical reconstructions of the alimentary habits at the court of Frederick II. Thus, old and new atmospheres, accompanied by the scent of aromas and suggestions inspired by the experience of each Author, come together to offer Readers fragments of everyday life at the court of Frederick II, in the 21st century
Angiotensin II modulates calponin gene expression in rat vascular smooth muscle cells in vivo.
No full textIt has been shown that angiotensin II (Ang II) induces the expression of calponin, a 34 kD actin-binding protein, in vascular smooth muscle cells in vitro. The aim of this study was to investigate whether Ang II can modulate calponin gene expression in rat aorta in vivo. Aortic calponin gene expression was studied after chronic exogenous Ang II administration and in Goldblatt hypertension. To investigate the effect of Ang II administration, Sprague Dawley rats were treated for 6 days with a continuous infusion of Ang II (200 ng/kg per min) or saline by osmotic minipumps. The effect of endogenous Ang II on aortic calponin mRNA expression was studied in Goldblatt hypertensive rats with (2K1C model), or without (1K1C model) activation of the renin-angiotensin system. In particular, calponin gene expression in 2K1C rats was studied both at 1 week (2K1C-HR, high renin) and 4 weeks after the onset of hypertension, when plasma renin activity (PRA) was returned to normal values (2K1C-NR, normal renin). Systolic blood pressure (SBP) was measured twice a week. At the end of the experimental period, PRA was measured by radioimmunoassay, and aortic calponin gene expression was measured by Northern hybridization. SBP was significantly higher (P < 0.01), whereas PRA was suppressed (P < 0.01), in Ang II versus saline-treated rats. Northern hybridization showed that the aortic calponin gene expression significantly increased (2.5-fold) in Ang II-treated rats (P = 0.01). In Goldblatt hypertensive rats, SBP was significantly higher in 2K1C-HR (P < 0.01), 2K1C-NR (P < 0.01) and 1K1C (P < 0.01) rats compared with the corresponding sham-treated rats. Activation of the renin-angiotensin system was present only in 2K1C-HR rats (P < 0.01), and Northern analysis showed that aortic calponin mRNA expression was significantly increased (2.2-fold) in this group of rats only (P < 0.01). Our data demonstrate that both exogenous and endogenous Ang II increase calponin gene expression in aortic smooth muscle cells, independently of the hemodynamic effect of Ang II
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