47,153 research outputs found
E. T. Pierce Ledger, 1883-1885
No full textLedger, 1883-1885, of E. T. Pierce, merchant [News Ferry, Halifax County, Va.] who sold tobacco fertilizers
Approximation of quadratic irrationals and their pierce expansions
No full textIn this article two aims are pursued: on the one hand, to present a rapidly converging algorithm for the approximation of square roots; on the other hand and based on the previous algorithm, to find the Pierce expansions of a certain class of quadratic irrationals as an alternative way to the method presented in 1984 by J.O. Shallit; we extend the method to find also the Pierce expansions of quadratic irrationals of the form which are not covered in Shallit's work.Quadratic irrationals, Pierce series
On a planar Pierce--Yung operator
No full textWe show that the operator \begin{equation*}
\mathcal{C} f(x,y) := \sup_{v\in \mathbb{R}} \Big|\mathrm{p.v.} \int_{\mathbb{R}} f(x-t, y-t^2) e^{i v t^3} \frac{\mathrm{d} t}{t} \Big| \end{equation*} is bounded on for every . This gives an affirmative answer to a question of Pierce and Yung.39 page
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Memorandum from A. E. Demaray to E. C. Finney
No full textFour letters of correspondence about the purchase of Bright Angel Trail between A. E. Demaray, Acting Director of the Grand Canyon National Park; E. C. Finney, Department of the Interior First Assistant Secretary; Carl T. Hayden, Representative (AZ); and Stephen T. Mather, Director of the National Park Service
Letter from Carl Hayden to T. E. Pollock, Arizona Central Bank
No full textLetter from T. E. Pollock to Carl Hayden asking his opinion on the proposed boundary lines
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
An alternative to breathing
No full textIf carbon dioxide is removed by an extracorporeal membrane lung ventilated with room air, the natural lung can be used for oxygen transport alone; we have demonstrated this in lambs by maintaining lungs "inflated" with 100 percent oxygen at constant pressure and removing all carbon dioxide through the membrane lung. This process is a variant of "apneic oxygenation" without its disadvantages, because the arterial pH, PCO2, and PO2 all remain normal. No nitrogen washout is needed. These studies were carried out in five lambs anesthetized and paralyzed for 24 hours. For carbon dioxide removal, blood from the subclavin artery was pumped through an extracorporeal membrane lung and was returned into the external jugular vein. For oxygen delivery, the lungs were inflated through a tracheostomy tube with 100 percent oxygen to a pressure of 5 cm. H2O. There was no significant change in arterial blood PO2 after perfusion had begun or at the end of the perfusion 24 hours later. The arterial PCO2 remained steady, and there was no change in acid-base balance. The functional residual capacity (FRC) and static lung compliance remained unchanged. The total dead space was 10 to 15 ml. All animals recovered and survived in good health. At equilibrium, alveolar nitrogen partial pressure was always equal to the partial pressure of nitrogen in the ventilating gas of the membrane lung and was the sole determining factor in controlling alveolar oxygen concentration. Direct measurement of pulmonary gas showed alveolar gas at the level of the carina
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
A new look at the pathogenesis of asthma
No full textAsthma is an inflammatory disorder of the conducting airways that has strong association with allergic sensitization. The disease is characterized by a polarized Th-2 (T-helper-2)-type T-cell response, but in general targeting this component of the disease with selective therapies has been disappointing and most therapy still relies on bronchodilators and corticosteroids rather than treating underlying disease mechanisms. With the disappointing outcomes of targeting individual Th-2 cytokines or manipulating T-cells, the time has come to re-evaluate the direction of research in this disease. A case is made that asthma has its origins in the airways themselves involving defective structural and functional behaviour of the epithelium in relation to environmental insults. Specifically, a defect in barrier function and an impaired innate immune response to viral infection may provide the substrate upon which allergic sensitization takes place. Once sensitized, the repeated allergen exposure will lead to disease persistence. These mechanisms could also be used to explain airway wall remodelling and the susceptibility of the asthmatic lung to exacerbations provoked by respiratory viruses, air pollution episodes and exposure to biologically active allergens. Variable activation of this epithelial-mesenchymal trophic unit could also lead to the emergence of different asthma phenotypes and a more targeted approach to the treatment of these. It also raises the possibility of developing treatments that increase the lung's resistance to the inhaled environment rather than concentrating all efforts on trying to suppress inflammation once it has become established.<br/
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