100,491 research outputs found
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Beyond ESPREssO - Integrative risk assessment 2025 synergies and gaps in climate change adaptation and disaster risk reduction
No full textClimate change including the more frequent occurrence and increased intensity of extreme climate events are important drivers of disaster events. This causality is accompanied by the fact that long-term impacts of climate change are connected with a high-level of uncertainty: complex interactions, feedback loops and underlying nonlinear effects that describe the consequences in this dynamic context. Special modelling approaches are required to increase understanding of these connections with climate change and related global issues, like environmental, social, economic and political matters. Resilience is a concept that can be used when tackling climate change impacts and decrease vulnerabilities. The holistic concept goes parallel with the understanding of “managing risks instead of managing disasters”! This contribution elaborates now this line of thought and characterizes a risk-oriented modelling and design-oriented perspective. We present overviews on climate change adaptation (CCA) and disaster risk reduction (DRR), respectively, and the related frameworks and methods. Finally, we consider the links between the ESPREssO project with the PLACARD experience as coordination action. Similarities and differences are characterized in detail. Based on this specific comparison, we propose a solution-oriented approach which might overcome the distinctions regarding the different approaches of the projects towards a transformational resilience management perspective, summarizing synergies and gaps as an example for integrative risk assessment beyond ESPREssO. We conclude with a comprehensive framework based on the 5 priority areas (referred as “mission”, terminology introduced in the Horizon Europe Framework) included in the final document of ESPREssO, which could be seen as an example for an integrative risk management combining quantitative and qualitative approaches
Rim-brominated pillarplexes and their assembly via self-sorting
No full textWe report rim-brominated pillarplexes, new examples of functionalised supramolecular organometallic complexes (SOCs). The bromide atoms can be introduced to the established pristine ligand precursor, demonstrating late-stage diversification of our ligand platform. SC-XRD/ED-derived crystal structures of precursor and pillarplex salts are reported along with competitive assembly experiments of the Ag(i) pillarplex, showing narcissistic self-sorting behavior
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
Wave turbulence of a rotating array of quantized vortices in the T → 0 temperature limit
No full textThe dynamics of quantized vortices in the zero temperature limit is currently of great interest, particularly in the case of the Fermi superfluid He-B. Here we study wave turbulence, generated by the librating motion of a rotating cylindrical container filled with He-B, in the limit of vanishing viscous forces at temperatures . The polarization of the quantized vortices with respect to the axis of rotation is measured using non-invasive NMR techniques. We observe a decrease of the polarization when the librating motion is started, and a two-stage relaxation process when the modulation of the rotation velocity is stopped. The first relaxation process is associated with the dissipation of large-scale flow stored in inertial waves and the solid body rotation of the vortex array. From the decay of these energy reservoirs we determine the rate of energy dissipation of large-scale flow. The later second process is related to the relaxation of Kelvin waves on individual vortices. This process is monitored by the recovery of the polarization. The existence of a Kelvin wave cascade at the lowest temperatures is currently a central open question. We supply some evidence for the cascade
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