133,862 research outputs found
The Pick Knitwear Story: 1856-1956
No full textAn account of
]. PICK & SONS LTD LEICESTER
Manufacturers for a hundred years. 45 page company publication
The Pick Knitwear Story, Book Two: 1956-1991
No full textAn account of
]. PICK & SONS LTD LEICESTER
Manufacturers for a hundred years. 45 page company publication
Performance Approximation and Design of Pick-and-Pass Order Picking Systems
No full textIn this paper, we discuss an approximation method based on G/G/m queuing network modeling using Whitt’s (1983) queuing network analyzer to analyze pick-and-pass order picking systems. The objective of this approximation method is to provide an instrument for obtaining rapid performance estimates (such as order lead time and station utilization) of the order picking system. The pick-and-pass system is decomposed into conveyor pieces and pick stations. Conveyor pieces have a constant processing time, whereas the service times at a pick station depend on the number of order lines in the order to be picked at the station, the storage policy at the station, and the working methods. Our approximation method appears to be sufficiently accurate for practical purposes. It can be used to rapidly evaluate the effects of the storage methods in pick stations, the number of order pickers at stations, the size of pick stations, the arrival process of customer orders, and the impact of batching and splitting orders on system performance.simulation;warehousing;order picking;queuing network;pick-and-pass
Order batching in multi-server pick-and-sort warehouses.
No full textIn many warehouses, customer orders are batched to profit from a reduction in the order picking effort. This reduction has to be offset against an increase in sorting effort. This paper studies the impact of the order batching policy on average customer order throughput time, in warehouses where the picking and sorting functions are executed separately by either a single operator or multiple parallel operators. We present a throughput time estimation model based on Whitt's queuing network approach, assuming that the number of order lines per customer order follows a discrete probability distribution and that the warehouse uses a random storage strategy. We show that the model is adequate in approximating the optimal pick batch size, minimizing average customer order throughput time. Next, we use the model to explore the different factors influencing optimal batch size, the optimal allocation of workers to picking and sorting, and the impact of different order picking strategies such as sort-while-pick (SWP) versus pick-and-sort (PAS)Order batching; Order picking and sorting; Queueing; Warehousing;
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Doença de Niemann Pick tipo B: relato de caso
No full textIntroduction: Niemann-Pick Disease (NPD) is a rare genetic condition, an autosomal recessive disorder, that can be identified by the acid sphingomyelinase deficiency, which leads to the buildup of sphingomyelin on lysosomes. The NPD is categorized into three main subclassifications: A, B, and C, each one with different clinical manifestations and phenotype variabilities. Case report: A 42-years-old male patient diagnosed in childhood with NPD-B under conditions of increased abdominal volume, medical follow-up was interrupted during pre-adolescence. In adulthood, the patient was referred to hepatology outpatient after gingivorrhagia, and epistaxis, it has been detected hepatosplenomegaly, portal hypertension, anemia, and thrombocytopenia. The medical records reviews showed a hepatic biopsy within anatomopathological results suggesting deposit disease and a myelogram within indication of foam cells, both examinations were performed during childhood. A chest tomography was performed, leading to the diagnosis of interstitial lung disease, although asymptomatic. The echocardiogram revealed a moderate to severe aortic stenosis, without clinical repercussions. On further investigation, it was detected sphingomyelinase deficiency (SMPD1), compatible with diagnoses of NPD type B. Discussion: NPD-B presents with significant phenotypic heterogeneity, which may include hepatosplenomegaly, portal hypertension, and hematologic involvement, leading to complications such as anemia and thrombocytopenia. Pulmonary involvement is common and manifests as interstitial lung disease. Primary cardiac involvement is not typical, but secondary complications may occasionally lead to cardiac manifestations. Conclusion: Early diagnosis and continuous follow-up are crucial for the proper management of Niemann-Pick Disease type B. The introduction of modified therapies, such as Olipudase alfa, brings significant hope for treatment. The reported experience highlights the need to increase awareness about the disease, improve early detection strategies, and ensure continuous monitoringIntrodução: A Doença de Niemann-Pick (DNP) é uma condição genética rara, autossômica
recessiva, descrita pela deficiência da esfingomielinase ácida, levando ao acúmulo de
esfingomielina nos lisossomos. A DNP é dividida em três subtipos principais: A, B e C, cada
um com manifestações clínicas distintas e variabilidade fenotípica. Relato de caso: Paciente
masculino de 42 anos diagnosticado com DNP tipo B na infância, a partir de investigação de
quadro de aumento de volume abdominal, porém com interrupção do acompanhamento médico
na pré-adolescência. Na idade adulta, foi encaminhado ao ambulatório de hepatologia devido
episódios de gengivorragia e epistaxe, sendo constatada hepatoesplenomegalia, hipertensão
portal, anemia e plaquetopenia. Revisão de prontuário mostrou biópsia hepática com resultado
anatomopatológico sugestivo de doença de depósito e mielograma com achado de células
espumosas, ambos exames realizados na infância. Submetido a tomografia de tórax, sendo
diagnosticado com doença intersticial pulmonar, embora assintomático. Ecocardiograma
evidenciou estenose aórtica moderada a grave, sem repercussões clínicas. Prosseguida
investigação, detectou-se de deficiência de atividade de esfingomielinase (SMPD1), compatível
com diagnóstico de DNP tipo B. Discussão: A DNP tipo B se apresenta com grande
heterogeneidade fenotípica, podendo ter hepatoesplenomegalia, hipertensão portal e
comprometimento hematológico, levando a complicações como anemia e plaquetopenia. O
acometimento pulmonar é frequente e se manifesta como doença intersticial. Envolvimento
cardíaco primário não é típico, mas complicações secundárias podem ocasionalmente levar a
manifestações cardíacas. Conclusão: Diagnóstico precoce e o acompanhamento contínuo são
fundamentais para o manejo adequado do DNP tipo B. A introdução de terapias modificadas,
como a Olipudase alfa, traz esperanças significativas para o tratamento. A experiência relatada
ressalta a necessidade de aumentar a conscientização sobre a doença, melhorar as estratégias de
detecção precoce e de monitoramento contínuo
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Une monnaie du ΚΟΙΝΟΝ ΑΡΜΕΝΊΑΣ
No full textPick B. Une monnaie du ΚΟΙΝΟΝ ΑΡΜΕΝΊΑΣ . In: Revue des Études Anciennes. Tome 16, 1914, n°3. pp. 283-289
Promethean Parenting: the family of Niemann-Pick patients.
No full textThe Niemann-Pick is an autosomal, recessive, rare and with a variable genomic imprinting disease. It involves three phenotypicalities (MNP-A, MNP-B, MNP-C) that differ by age of onset, symptoms and complexity of prognosis with a rather linear maintenance of symptoms. This chapter examines the psychological outcomes implied in the pathway of this disease. More specifically, it considers this pathway as potentially traumatizing and explores the emotional impact of a rare metabolic syndrome both at an individual and family level. Possible psychological consequences result from a complex interplay of negative emotions such as guilt, shame, helplessness, fear, anger in conjunction with patterns of resilience
Development and Management of a Pick & Place Industrial Robot System
No full textreservedIl mondo dell’industria robotica è sempre più diffuso in molte realtà e, con loro, c’è sempre più necessità di software engineers e personale specializzato.
Ci sono vari ambienti e rami nel mondo della robotica e, in particolare, noi tratteremo di un problema in questa tesi: il Pick & Place.
Il Pick & Place coinsiste nel pensare e progettare a come dei robot possano spostare degli oggetti da un punto A ad un punto B, rispettando dei vincoli predeterminati come l’ordine della sequenza, posizione degli oggetti ecc..
Nella mia tesi presenterò il progetto sviluppato presso PFM, azienda che ha fornito gli strumenti per lo sviluppo:
Un sistema software di gestione di robot Rockwell che effettuano operazioni di Pick & Place
Il progetto è stato sviluppato e testato nel periodo di stage (7/8 mesi) in diverse fasi.
La tesi è divisa in 3 parti:
1. Dialogo con l’azienda per capire come approcciarsi al caso di studio (nastro + contronastro con più robot che spostano oggetti dal primo al secondo nastro)
2. Sviluppo di un simulatore su MatLab per analizzare le prestazioni di diverse logiche di presa
3. Passaggio della logica in ambiente PLC attraverso i linguaggi LD (Ladder Diagram) e ST (Structured Text) in ambiente Studio5000The world of robotics is becoming increasingly prevalent in many realities, and with them, there is an increasing need for software engineers and specialized personnel.
There are various environments and branches in the world of robotics and we will deal with one problem in this thesis: Pick & Place.
Pick & Place consists in thinking and designing how robots can move objects from point A to point B, respecting predetermined constraints such as the order of the sequence, position of the objects, etc...
In my thesis, I will present the project developed in PFM, the company that provided the tools for development:
A software system for managing Rockwell robots performing Pick & Place operations.
The thesis is divided into three parts:
1. Dialogue with the company to understand how to approach the case study (belt + counter-belt with several robots moving objects from the first to the second belt)
2. Development of a simulator on MatLab to analyse the performance of different pick logics
3. Transfer in PLC environment through LD (Ladder Diagram) and ST (Structured Text) languages in Studio5000 environmen
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