93 research outputs found
Personality and Work of Jan Nepomuk Polasek (1873-1956)
No full textThis dissertation thesis focuses on the person and work of Jan Nepomuk Polášek (1873-1956), a distinguished regional composer and music teacher who spent a significant part of his life in Valašské Meziříčí. Throughout his life, Polášek devoted himself to creative work, which was, to a varying degree, inspired by the Moravian Wallachian folk culture. The thesis outlines the important phases of Polášek's life including his childhood and school days, first contact with music teaching, his studies at the Brno Organ School, and, last but not least, his relationship with Leoš Janáček. The Biographical part of the thesis ends with a subchapter devoted to Polášek's work in Valašské Meziříčí until his death in 1956. Polášek's body of work includes his compositions, music-related organisational activities, music teaching, publishing and folk song collecting. The aforementioned activities are presented and analysed in the remaining chapters of this dissertation thesis. The final chapter analyses selected instrumental, vocal-instrumental and vocal compositions of Polášek's, based on which it illustrates the key elements of his creative work. The thesis presents some entirely new findings regarding the life and work of Jan Nepomuk Polášek that are founded on many information sources the author obtained. Key..
Personality and Work of Jan Nepomuk Polasek (1873-1956)
No full textThis dissertation thesis focuses on the person and work of Jan Nepomuk Polášek (1873-1956), a distinguished regional composer and music teacher who spent a significant part of his life in Valašské Meziříčí. Throughout his life, Polášek devoted himself to creative work, which was, to a varying degree, inspired by the Moravian Wallachian folk culture. The thesis outlines the important phases of Polášek's life including his childhood and school days, first contact with music teaching, his studies at the Brno Organ School, and, last but not least, his relationship with Leoš Janáček. The Biographical part of the thesis ends with a subchapter devoted to Polášek's work in Valašské Meziříčí until his death in 1956. Polášek's body of work includes his compositions, music-related organisational activities, music teaching, publishing and folk song collecting. The aforementioned activities are presented and analysed in the remaining chapters of this dissertation thesis. The final chapter analyses selected instrumental, vocal-instrumental and vocal compositions of Polášek's, based on which it illustrates the key elements of his creative work. The thesis presents some entirely new findings regarding the life and work of Jan Nepomuk Polášek that are founded on many information sources the author obtained. Key...Disertační práce se zabývá osobností a dílem J. N. Poláška (1873-1956), významného regionální hudebního skladatele a pedagoga, který podstatnou část svého života prožil ve Valašském Meziříčí. Polášek se v průběhu svého života věnoval tvůrčí činnosti, do které v různé míře prostupovaly prvky valašské lidové kultury. Práce mapuje důležité životní etapy Poláškova života, zmiňuje dětská a školní léta, první kontakty s hudebním vzděláváním, studia na varhanické škole v Brně, přičemž neopomíjí ani setkání s Leošem Janáčkem. Biografická část je zakončena podkapitolou, která se věnuje Poláškovu působení ve Valašském Meziříčí až do jeho smrti v roce 1956. Stěžejní dílo Jana Nepomuka Poláška představuje kompoziční tvorba a jeho hudebně-organizační, pedagogická, publikační a sběratelská činnost. Uvedenými aktivitami a jejich analýzou se zabývá významná část disertační práce. V závěrečné části práce se nachází analýza vybraných Poláškových instrumentálních, vokálně-instrumentálních a vokálních skladeb, na jejichž základě jsou ukázány charakteristické prvky, které se v Poláškově tvorbě vyskytují. V předkládaném textu uvádíme zcela nová zjištění týkající se života a tvůrčích aktivit Jana Nepomuka Poláška, která se opírají o značné množství získaných pramenů. Klíčová slova: Jan Nepomuk Polášek, Valašsko, Valašské...Katedra hudební výchovyFaculty of EducationPedagogická fakult
Profiles of visitors at south Bohemia tourist destination
No full textBakalářská práce měla za cíl sestavit na základě kvantitativního výzkumu profily návštěvníků jižních Čech, identifikovat potřeby a požadavky návštěvníků a provést segmentaci trhu na straně poptávky. Teoretická část vymezuje pojmy jako je destinace, účastník cestovního ruchu, poptávka a nabídka cestovního ruchu, marketing destinace a udržitelný cestovní ruch. V praktické části je vymezena destinace jižní Čechy a vyhodnocena data z kvantitativního výzkumu, která jsou doplněna o data ze strukturovaného rozhovoru s panem Ing. Jaromírem Poláškem, ředitelem Jihočeské centrály cestovního ruchu. Na základě těchto dat je provedena syntéza výsledků a poznatků a sestaven profil návštěvníků destinace. Výstupem návrhové části jsou navržené klíčové a perspektivní cílové segmenty pro udržitelný rozvoj, vytvořené persony jednotlivých segmentů a zhodnocena jejich ekonomická perspektiva.ObhájenoThe aim of the Bachelor's thesis was to compile visitors' profiles of the South Bohemia tourism destination on the basis of quantitative research, identify the needs and requirements of visitors and segment the market on the side of demand. The theoretical part defines terms such as destination, participant in tourism, demand and supply of tourism, destination marketing and sustainable tourism. The practical part defines the South Bohemia tourism destination and evaluates data from quantitative research, which are supplemented with data from a structured interview with Mr. Ing. Jaromir Polasek, who is director of the South Bohemian Tourist Board. On the base of these data is carried out synthesis of results and knowledge, and is compiled a profile of destination visitors. The outputs of the design part are: the proposed key and promising target segments for sustainable development, the created persons of individual segments and evaluated their economic perspective
Modification of Polyvinyl Chloride Composites for Radiographic Detection of Polyvinyl Chloride Retained Surgical Items
No full textThe ever-present risk of surgical items being retained represents a real medical peril for the patient and potential liability issues for medical staff. Radiofrequency scanning technology is a very good means to substantially reduce such accidents. Radiolucent medical-grade polyvinyl chloride (PVC) used for the production of medical items is filled with radiopaque agents to enable X-ray visibility. The present study proves the suitability of bismuth oxychloride (BiOCl) and documents its advantages over the classical radiopaque agent barium sulfate (BaSO4). An addition of BiOCl exhibits excellent chemical and physical stability (no leaching, thermo-mechanical properties) and good dispersibility within the PVC matrix. As documented, using half the quantity of BiOCl compared to BaSO4 will provide a very good result. The conclusions are based on the methods of rotational rheometry, scanning electron microscopy, dynamic mechanical analysis, atomic absorption spectroscopy, and the verification of zero leaching of BiOCl out of a PVC matrix. X-ray images of the studied materials are presented, and an optimal concentration of BiOCl is evaluated
Software Model Creation with Multidimensional UML
No full textPart 11: Social Impact of EIS and VisualizationInternational audienceThe aim of the paper is to present the advantages of the Use Cases transformation to the object layers and their visualization in 3D space to reduce complexity. Our work moves selected UML diagram from two-dimensional to multidimensional space for better visualization and readability of the structure or behaviour.Our general scope is to exploit layers for particular components or modules, time and author versions, particular object types (GUI, Business services, DB services, abstract domain classes, role and scenario classes), patterns and anti-patterns in the structure, aspects in the particular layers for solving crosscutting concerns and anti-patterns, alternative and parallel scenarios, pessimistic, optimistic and daily use scenarios.We successfully apply force directed algorithm to create more convenient automated class diagrams layout. In addition to this algorithm, we introduced semantics by adding weight factor in force calculation process
Short-term streambed drying events alter amphipod population structure in a central European stream
No full textTemporary streams are becoming increasingly common, but ecological responses to streambed drying are poorly characterized in the temperate continental region of central Europe. In addition, global research has focused on community responses to drying, whereas effects on individual populations remain unknown. We explored the population structure of Gammarus fossarum (Crustacea: Amphipoda) in a central European temporary stream. Benthic gammarids were sampled on five dates during a flow recession, one date between two drying events (of 10 and 20 days, respectively), and five dates after flow resumed. Additional benthic samples were taken from isolated pools and dry sediments during drying events, and freeze cores were collected to compare the vertical distribution of amphipods during wet and dry phases. Gammarids were measured, adults distinguished from juveniles, adults sexed, and female reproductive state determined. Densities increased during flow recession, potentially reflecting both a decline in submerged habitat availability and seasonal increases in juvenile abundance. Persistence within dry benthic sediments was minimal, whereas pools and saturated subsurface sediments supported high population densities. Juveniles comprised 80 % of the subsurface population, suggesting that their ability to inhabit small interstices promotes persistence within the dry reach. Juveniles also comprised 92 % of pool inhabitants, despite their potential exposure to predation. Adults dominated after flow resumed, and population structure was altered post-drying by the loss of spring-recruited juveniles and reproductive females. Our results suggest that streambed drying may have longer-term effects than typically characterized by community-level studies. We recommend management actions that support populations of ecologically important species as they adapt to changing flow regimes
Hundreds of variants clustered in genomic loci and biological pathways affect human height
No full textMost common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human traits(1), but these typically explain small fractions of phenotypic variation, raising questions about the use of further studies. Here, using 183,727 individuals, we show that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait(2,3). The large number of loci reveals patterns with important implications for genetic studies of common human diseases and traits. First, the 180 loci are not random, but instead are enriched for genes that are connected in biological pathways (P = 0.016) and that underlie skeletal growth defects (P<0.001). Second, the likely causal gene is often located near the most strongly associated variant: in 13 of 21 loci containing a known skeletal growth gene, that gene was closest to the associated variant. Third, at least 19 loci have multiple independently associated variants, suggesting that allelic heterogeneity is a frequent feature of polygenic traits, that comprehensive explorations of already-discovered loci should discover additional variants and that an appreciable fraction of associated loci may have been identified. Fourth, associated variants are enriched for likely functional effects on genes, being over-represented among variants that alter amino-acid structure of proteins and expression levels of nearby genes. Our data explain approximately 10% of the phenotypic variation in height, and we estimate that unidentified common variants of similar effect sizes would increase this figure to approximately 16% of phenotypic variation (approximately 20% of heritable variation). Although additional approaches are needed to dissect the genetic architecture of polygenic human traits fully, our findings indicate that GWA studies can identify large numbers of loci that implicate biologically relevant genes and pathways
Author Correction: A global analysis of terrestrial plant litter dynamics in non-perennial waterways
No full text© 2018 The Author(s) In the version of this Article originally published, the affiliation for M. I. Arce was incorrect; it should have been:5Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB), Berlin, Germany. This has now been corrected in the online versions of the Article
Planning Telehealth for Older Adults With Atrial Fibrillation in Rural Communities: Understanding Stakeholder Perspectives
No full text Older adults with atrial fibrillation (AF) in rural communities have less access to cardiac specialty care. Telehealth offers a viable approach to provide cardiac care, yet little is known about patients’ and providers’ views on telehealth’s potential to support rural patients with AF. This qualitative descriptive study examines patient and health providers’ perspectives, an important first step in planning a telehealth initiative. Eight patients with AF, along with one partner from rural communities, were recruited through an urban-based AF clinic. Five providers were recruited through professional practice leads in the health region. Semistructured telephone interviews were conducted with both stakeholder groups. The overriding theme was variability in patient and provider receptiveness to telehealth. Receptiveness reflected differences in past experience with telehealth, in perceived adequacy of rural health services, and in perceived gaps in AF care. These are important considerations in planning effective and sustainable telehealth in rural communities. </jats:p
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
No full textElevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and confirmed associations with all 7 previously established loci. Experimental downregulation of gene expression in Drosophila melanogaster and Danio rerio identified 20 genes at 11 loci that are relevant for heart rate regulation and highlight a role for genes involved in signal transmission, embryonic cardiac development and the pathophysiology of dilated cardiomyopathy, congenital heart failure and/or sudden cardiac death. In addition, genetic susceptibility to increased heart rate is associated with altered cardiac conduction and reduced risk of sick sinus syndrome, and both heart rate-increasing and heart rate-decreasing variants associate with risk of atrial fibrillation. Our findings provide fresh insights into the mechanisms regulating heart rate and identify new therapeutic targets
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