10 research outputs found

    Looking for Ladies: Finding Women in Local Resources

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    Women's philanthropy in Northampton is deeply entwined with the Boot and Shoe Industry. Many of the manufacturers were heavily involved in political, religious and general civic matters and as a result so were their wives and daughters. Finding women in a local history study such as this can be challenging. By considering a variety of local resources, however, it is possible to gain an understand of the philanthropic activities of these women

    Women's philanthropy and religion:The ladies of the Northampton shoe trade, 1870-1950

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    This paper considers the role in which women played within religious organisations within the 19th and 20th centuries. Using the Northampton Boot and Shoe industry as a focus, it will explore the philanthropic activities carried out by women connected to the industry, and how they were able to support the local churches. The paper also considers the importance of women's history within a local history study as well as showing women's contribution to society and their local community

    Looking for Ladies: Finding Women in Local Resources

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    Women's philanthropy in Northampton is deeply entwined with the Boot and Shoe Industry. Many of the manufacturers wereheavily involved in political, religious and general civic matters and as a result so were their wives and daughters. Findingwomen in a local history study such as this can be challenging. By considering a variety of local resources, however, it ispossible to gain an understand of the philanthropic activities of these women

    A post-mortem toxicological investigation: Understanding the role of drugs of abuse in violent fatalities in Cape Town, South Africa

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    Violence and resulting injuries are critical health burdens worldwide, accounting for the death of millions of individuals annually. The literature reports an association between drug use and violence, providing data indicating that the use of psychoactive substances increases the risk of morbidity and mortality due to violent acts. South Africa has a long history of violence, with one of the highest rates of recorded violence- and injury-related deaths in the world. This is complicated by an increase in illicit substance use and abuse, particularly in the Cape Town Metropole, located within the Western Cape Province. The use of toxicological findings from victims of violent death (homicides, suicides, and accidents) to examine community-specific drug-related violence is slowly increasing in different parts of the world. In South Africa, however, monitoring drug trends in violent fatalities using toxicological analysis is uncommon, and hence drug toxicology of violent-related fatalities is limited. Divided into three contextual sections, this research study focuses on the post-mortem toxicology of violent deaths in a South African setting. The first section provides a general idea of the research problem and an initial development of the investigation process. The second section provides a theoretical basis for performing routine toxicological analyses in deaths due to violence, reports important research work conducted in the field worldwide, and emphasizes the need to monitor toxicological data derived from violent fatalities in Cape Town, South Africa. The last section, in the form of a manuscript, presents the overall research study including the methodology, outcomes, and concluding findings in a concise and illustrative manner. The primary aim of this pilot study was to investigate the prevalence and characteristics of illicit substances in violent fatalities (homicides, suicides, and accidents) of the Salt River mortuary in Cape Town, South Africa. The objectives were to conduct a comprehensive drug toxicology analysis to generate qualitative and comparative data from the aforementioned cases. In addition, this study investigated the dynamics between psychoactive substance use and violent deaths in terms of toxicological trends, and the demographics and circumstances of death of the victim. Lastly, the author discusses potential qualitative associations between illicit substances and violence-related deaths in a South African setting, and provide suggestions for future toxicological analyses in these fatalities

    Cold plasma treatment of rice: A bibliometric analysis

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    The use of cold plasma (CP) technology in rice processing has gained global attention. A bibliometric analysis explored research trends, collaboration opportunities, and key concerns in CP treatment of rice. The analysis aimed to highlight the substantial increase in scholarly publications since 2013. It focused on rice decontamination and storage improvement using CP treatment. The study revealed that China, India, and Thailand, leading rice-producing nations, were also at the forefront of CP treatment research. South Korean author Min, S.C., with six publications, made a noteworthy contribution. Most articles on CP treatment of rice resulted from domestic collaborations, but China and India actively engaged in global partnerships, indicating a growing interest in international research. These findings suggest an inclination towards fostering international collaborations in CP treatment of rice. Overall, this investigation contributes significantly to the academic community, offering insights into the current research landscape. The study also provides recommendations for future directions in managing CP treatment of rice. This bibliometric analysis serves as a valuable reference for scholars interested in the emerging CP treatment technology in the rice sector

    Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries The International Surgical Outcomes Study group

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    Funded by Nestle Health Sciences through an unrestricted research grant, by a National Institute for Health Research Professorship held by R.P., and sponsored by Queen Mary University of London

    Perspectives on ENCODE

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    The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression1. The project has been extended to model organisms, particularly the mouse. In the third phase of ENCODE, nearly a million and more than 300,000 cCRE annotations have been generated for human and mouse, respectively, and these have provided a valuable resource for the scientific community.11Nsciescopu

    Expanded encyclopaedias of DNA elements in the human and mouse genomes

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    AbstractThe human and mouse genomes contain instructions that specify RNAs and proteins and govern the timing, magnitude, and cellular context of their production. To better delineate these elements, phase III of the Encyclopedia of DNA Elements (ENCODE) Project has expanded analysis of the cell and tissue repertoires of RNA transcription, chromatin structure and modification, DNA methylation, chromatin looping, and occupancy by transcription factors and RNA-binding proteins. Here we summarize these efforts, which have produced 5,992 new experimental datasets, including systematic determinations across mouse fetal development. All data are available through the ENCODE data portal (https://www.encodeproject.org), including phase II ENCODE1 and Roadmap Epigenomics2 data. We have developed a registry of 926,535 human and 339,815 mouse candidate cis-regulatory elements, covering 7.9 and 3.4% of their respective genomes, by integrating selected datatypes associated with gene regulation, and constructed a web-based server (SCREEN; http://screen.encodeproject.org) to provide flexible, user-defined access to this resource. Collectively, the ENCODE data and registry provide an expansive resource for the scientific community to build a better understanding of the organization and function of the human and mouse genomes.11Nsciescopu
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