1,720,973 research outputs found

    Perbandingan Kadar Hemoglobin Pra Dan Pasca Hemodialisa Pada Pasien Penderita Gagal Ginjal Kronik Di RSUD Karawang

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    Gagal Ginjal adalah hilangnya fungsi ginjal, dan dibagi menjadi dua kategori yaitu gagal ginjal akut dan gagal ginjal kronik. Gagal Ginjal Kronik adalah suatu keadaan klinis yang ditandai dengan penurunan fungsi ginjal yang irreversible, pada suatu derajat yang memerlukan terapi pengganti ginjal yang tetap, berupa dialisis atau transplantasi ginjal. Penyakit Gagal Ginjal Kronik (GGK) prevalensinya semakin meningkat setiap tahunnya di negara-negara berkembang termasuk Indonesia yang diperkirakan ada sekitar 40-60 kasus per juta penduduk per tahun. Hemodialisa merupakan salah satu terapi yang rutin dilakukan pada pasien Gagal Ginjal Kronik. Penelitian ini bertujuan untuk mengetahui kadar hemoglobin pada penderita gagal ginjal kronik pra dan pasca hemodialisa. Penelitian ini dilakukan terhadap 50 pasien penderita gagal ginjal kronik di RSUD Karawang periode Maret-Juni 2018. Data diperoleh dari bagian Rekam medik RSUD Karawang. Data diambil dan dicatat dari formulir rekam medis mengenai kadar Hb pada pasien Gagal Ginjal Kronik pra dan pasca hemodialisa. Data diuji statistik dengan uji Paired Sample T-Test.Dari hasil penelitian ini diperoleh nilai rata-rata kadar hemoglobin pra hemodialisa adalah 8.4 g/dl, dengan kadar terendah 7.0 g/dl dan kadar tertinggi 10.3 g/dl. Sedangkan nilai rata-rata kadar hemoglobin pasca hemodialisa adalah 9.0 g/dl, dengan kadar terendah 7.3 g/dl dan kadar tertinggi 10.6 g/dl. Terdapat perbedaan yang signifikan antara kadar hemoglobin pra hemodialisa dengan kadar hemoglobin pasca hemodialisa. Kata Kunci     : Gagal Ginjal Kronik, Hemodialisa, Hemoglobi

    Gambaran Kadar Hemoglobin(Hb) Dan Leukosit Pada Penderita Tb Paru Dengan Lamanya Terapi OAT (Obat Anti Tuberculosis) Di Rumah Sakit Islam Jakarta Cempaka

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    Penderita TB Paru masih banyak di Indonesia termasuk di Ibu kota Jakarta. Efek yang timbul baik yang melaksanakan pengobatan maupun yang sementara pengobatan adalah anemia. Tujuan penelitian memperoleh gambaran kadar hemoglobin dan leukosit pada penderita TB Paru di Rumah Sakit Islam Cempaka Putih. Penelitiang ini menggunakan metode deskriptif populasi dalam penelitian ini adalah penderita TB paru yang masih melakukan pengobatan.Hasil penelitian menunjukan bahwa kadar hemoglobin penderita TB paru di RSIJ Cempaka Putih sebanyak 34 orang (31%) memiliki kadar hemoglobin yang normal dan sebanyak 75 orang (69%) memiliki kadar hemoglobin yang tidak normal, sedangkan nilai rata-rata leukosit sebanyak 70orang (64%) memiliki nilai leukosit yang normal dan 39 orang (36%) memiliki nilai leukosit yang tidak normal.Dari hasil penelitian dapat disimpulkan sebanyak 75 orang (69%) memiliki kadar hemoglobin yang tidak normal dan 39 orang (36%) memiliki nilai leukosit yang tidak normal. Kata kunci       : Hemoglobin, Leukosit, Penderita TB, OA

    Gambaran Hasil Pemeriksaan Neutrofil Limfosit Rasio, CRP dan D-Dimer Dalam Memantau Keparahan Pasien Positif Covid-19 Di Rumah Sakit Haji Jakarta Tahun 2022

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    Identifikasi awal dari indikator yang membedakan pasien COVID-19 yang parah dari yang sedang dapat memfasilitasi intervensi medis yang lebih cepat seperti perawatan intensif untuk yang sakit kritis, sehingga menurunkan tingkat kematian dan mengoptimalkan penggunaan sumber daya medis. Tujuan penelitian ini adalah identifikasi dini pasien COVID-19 dengan gejala berat melalui pemeriksaan Neutrofil Limfosit rasio, CRP dan D-Dimer, sehingga pasien COVID-19 dengan gejala berat dapat ditangani lebih dini dan tidak berakhir dengan kematian. Target khusus penelitian ini untuk mengetahui bagaimana gambaran hasil pemeriksaan Neutrofil Limfosit rasio, CRP dan D-Dimer dalam memantau keparahan  pasien positif COVID-19. Metode penelitian yang digunakan adalah desain cross sectional. Jumlah sampel sebanyak 108 pasien COVID-19 dengan kondisi parah berdasarkan data rekam medik periode Juni 2020-Desember 2021. Hasil penelitian menunjukkan terjadi peningkatan 82% pada hasil Netrofil Limfosit rasio (rerata 6,2), 100% pada hasil pemeriksaan CRP (rerata 34,8 mg/L) dan D-Dimer (2,5 mg/L), dengan korelasi kuat (r= 0,67) dan signifikansi hubungan 0,01 (< 0,05). Simpulan pemeriksaan Netrofil Limfosit rasio, CRP dan D-Dimer dapat digunakan untuk memprediksi tingkat keparahan pada pasien COVID-19.Kata kunci:   COVID-19, Neutrofil Limfosit rasio, CRP, D-DimerÂ

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Uji Daya Hambat Antibakteri Kombinasi Ekstrak Kulit Buah Manggis Komersial (Garcinia mangostana L) dan Amoksisilin Terhadap Bakteri Methicillin Resistant Staphylococcus aureus (MRSA)

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    Amoxicillin is a beta-lactam antibiotic compound and has the chemical name alpha-amino-hydroxylbenzyl-penicillin. This drug was initially developed to have an advantage over ampicillin: it can be better absorbed in the digestive tract. The chemical contents of mangosteen rind (KBM) are xanthone, mangostin, garcinone, flavonoids and tannins. In addition, mangostenol, mangostenone A, mangostenone B, trapezifolixanton, tovofilin B, alpha mangostin, beta mangostin, garsinone B, mangostinone, epicatechin, and mangostanol. Mangosteen (Garcinia Mangostana L.) has many pharmacological properties; KBM also has antimicroorganism properties. It is estimated that alpha mangostin and/or KBM extract works in a similar way to amoxicillin, namely stopping the formation of bacterial cell walls. Alpha mangostin (flavonoid) or KBM extract (clavulanic acid) have similar groups or active substances. The aim of this research is to prove the antibacterial mechanism of action of the combination of KBM (Garcinia mangostana L) extract with amoxicillin on the growth of MRSA bacterial cells. Conclusion: The MIC of commercial GML extract, amoxicillin against MRSA is 137.50 µg/mL and 250.00 µg/mL respectively. The checkerboard test showed synergistic activity of commercial GML (34.38 µg/mL) plus amoxicillin (62.50 µg/mL) against Methicillin-Resistant Staphylococcus aureus (MRSA) or Staphylococcus aureus ATCC BAA-3. The FIC index of amoxicillin plus GML against MRSA strains was 0.50. The synergistic activity of this combination was confirmed by a 2 log10 CFU/mL reduction of these treated cells compared with amoxicillin treatment alone. Conclusion that the combination of commercial mangosteen peel extract and amoxicillin is able to inhibit the growth of Methicillin-Resistant Staphylococcus aureus (MRSA). Key words: Alpha mangostin, amoxicillin, Staphylococcus aureus, FI

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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