1,721,014 research outputs found
'Imagines erant futurorum'. Un'interpretazione dell'iconografia cristiana precostantiniana
No full textThis work regards the storiographical appraisal of the paleochristian artistic material: it chooses to acquire it like documentary source rather than like peripheral outcome of that historical phenomenon. Receiving this methodological formulation, it is possible to establish a strong nexus between the liturgical context and the development of the most ancient theological reflection. through a radical review of the appraisal of the documentary capacity of this source, it is possible to better specify the origin and the first development of the first Christianity.questo studio approfondisce la valutazione della rilevanza storiografica della documentazione visuale cristiana antica. scegliendo di assumere questo materiale come fonte primaria della ricerca, essa giunge a riconsiderare alcuni aspetti dei primi cristianesimi (ruolo della donna, indirizzi e tecniche esegetiche, paradigmi teologici, etc.). tramite il forte nesso con l'ambito liturgico, questa documentazione si rivela, dunue, capace di ampliare significativamente il panorama delle attuali conoscenz
Do platinum salts fit all triple negative breast cancers?
No full textTriple-negative breast cancer (TNBC) is an aggressive disease with limited treatment options and poor prognosis once metastatic. Pre-clinical and clinical data suggest that TNBC could be more sensitive to platinum-based chemotherapy, especially among BRCA1/2-mutated patients. In recent years, several randomised trials have been conducted to evaluate platinum efficacy in both early-stage and advanced TNBC, with conflicting results especially for long-term outcomes. Experimental studies are now focusing on identifying biomarkers of response to help selecting patients who may benefit most from platinum-based therapies, including BRCA1/2 mutational status and genomic instability signatures (such as HRD-LOH or HRD-LST scores). A standard therapy for TNBC is still missing and platinum-based regimens represent an emerging therapeutic option for selected patients with a defect in the homologous recombination repair system. The identification of these patients through validated biomarker assays will be crucial to optimize the use of currently approved agents in TNBC
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
I Segni premonitori del Giudizio Universale in un inedito testo tedesco del XV secolo
No full textNumerous lists of the premonitory signs of the Last Judgment and wider narratives focussing on the same motif, which presents variants and articulated typologies, circulated throughout the Middle Ages, both in Latin and in the vernacular languages. Also in Germany the motif continues to be present in literature up to the threshold of the modern age, with the Lutheran Reform which is, also in this case, a watershed.
The purpose of the contribution is the philological-literary analysis of a prose composition, in late German, devoted to the 15 Signs of Judgment, still unpublished, preserved in the ms. München, BStB cgm 522 (ff. 163v-166v), datable around 1470. The codex contains a miscellany of apocalyptic content, which also includes texts on the coming of the antichrist and on the Sibylline oracles. The text to be analysed is part of a more extensive work on the theme of the Last Judgment. The manuscript also contains an interesting set of illustrations relating to the events to which each of the Signs of Judgment alludes.
The study aims to investigate the textual and thematic peculiarities of this version of the 15 Signs, also in the light of the codicological context, as well as the relationship with the wider eschatological literary tradition of the German Middle Ages
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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