111,834 research outputs found
Totally laparoscopic right colectomy: theoretical and practical advantages over the laparo-assisted approach
Background: Because of its less evident advantages regarding patient recovery, the laparoscopic approach for right colectomy initially gained less popularity than for left colectomy.
The improvement in intracorporeal anastomotic techniques and the consequent switch from a laparo-assisted (LA) to a totally laparoscopic (TL) intervention seems to have overcome the initial concerns, giving rise to widespread use of such a procedure.
By comparing the LA and the TL approach, our study was aimed at verifying the possible advantages of the more recent technique, also focussing on some technical implications for the surgeon.
Methods: We prospectively collected and matched data from 27 consecutive laparo -assisted right colectomies (LARC) and 28 consecutive totally laparoscopic procedures (TLRC). Clinical, biochemical, pathological and cosmetic parameters were examined. Operating times were recorded and fractioned, in order to evaluate the learning curve for the different phases of the procedure.
Results: LA and TL groups were homogeneous for demographic and pathological features. We had no mortality, and surgical complication rates were similar (3.6% vs. 3.7%). The TLRC group presented a significantly shorter laparotomy (4.8 cm vs. 7.2 cm, p=0.002), while no significant difference was recorded for outcome parameters.
Operating time for carrying out anastomosis (TA) was significantly longer for the TL group (55.6 min vs. 20.6 min, p<0.0001). A rapid decrease in TA throughout the series attests to a short learning curve for intracorporeal ileo-transverse anastomosis.
Conclusions: Further studies are needed to demonstrate the possible clinical advantages of TLRC over the LA approach. The cosmetic benefit for patients along with the safety and the prospective usefulness for surgeons (practice in intracorporeal suturing techniques) would seem to justify an inclination towards this technical development
author-bios-SRD-19-0063.R1 – Supplemental material for The Network Structure of Police Misconduct
Supplemental material, author-bios-SRD-19-0063.R1 for The Network Structure of Police Misconduct by George Wood, Daria Roithmayr and Andrew V. Papachristos in Socius</p
Early onset of graft glomerulopathy in a patient with post-transplant diabetes mellitus after renal transplantation: a case report
Abstract Background Post-transplant diabetes mellitus (PTDM) is an emerging problem in kidney transplantation, representing an important risk factor for kidney function loss. Diabetic nephropathy (DN) occurrence in transplanted kidneys is poorly investigated. Current knowledge describes DN recurrence in graft 5.9 years from kidney transplantation however there is little data about PTDM and DN. Here, we report a clinical case peculiar for an early appearance of advanced glomerular diabetic lesions, after kidney transplantation. Case presentation A 45-year-old Caucasian male affected by autosomal polycystic kidney disease was transplanted with a cadaveric-kidney-donor from 58-year-old male. Induction immunosuppressive therapy included basiliximab and steroids while the maintenance treatment included, tacrolimus, mofetil micophenolate and methylprednisolone. One month after transplantation the patient developed diabetes requiring treatment with repaglinide quickly replaced with insulin to obtain an acceptable glycemic control (HbA1c 52 mmol/mol). Glycosuria was detected persistently during the first six months after transplantation. To achieve further improvement in glycemic control, a shift from tacrolimus to cyclosporine (CyA) was made and steroids were rapidly tapered and stopped. To minimize calcineurin inhibitors toxicity, which was revealed in the 1-year-protocol-biopsy, everolimus was introduced thereby lowering CyA through levels. Moderate hypertension was well controlled with doxazosin. Thirty months after transplantation a second graft biopsy was performed owing to renal function decline and microalbuminuria appearance. Histological analysis surprisingly showed mesangiolysis and microaneurysms; glomerular sclero-hyalinosis and basal membrane thickness and typical nodular glomerulosclerosis. C4d staining was negative and no evidence of immune deposits were detected. Donor Specific Antibodies, serum C3 and C4 levels and autoimmunity tests were negative. Retrospective analysis on donor history didn’t show diabetes or insulin resistance and no diabetic lesions were found in kidney pre-implant biopsy. Conclusions In our knowledge, this is the first report describing a very early onset of advanced diabetic glomerular lesions in a graft biopsy after PTDM. We hypothesize that additional factors such as everolimus and hypertension, may have contribute to kidney damage
Totally laparoscopic right colectomy: theoretical and practical advantages over the laparo-assisted approach.
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Využití sociálních médií v B2B prodeji
Tato diplomová práce se zabývá tím, jak mohou B2B obchodníci využívat sociální média v prodeji. Na základě systematické rešerše literatury, autor zjistil, že akademici, zkoumající danou problematiku, navrhují další výzkum, a to: v kterých konkrétních krocích se dají využít sociální média v prodeji (Salo, 2017). Autor se na základě toho rozhodl zjistit, jaké sociální sítě, různé technologie a pluginy se dají využít v B2B prodeji - tzv. social sellingu. Social selling se v této práci týká primárně procesu akvizice a okrajově péčí o stávající zákazníky. Autor si vybral kvalitativní průzkum pomocí 10 hloubkových polo-strukturovaných rozhovorů, aby odhalil jak, která sociální média to jsou, tak i motivaci prodejců, proč tato média používat/nepoužívat. Aby autor dodržel správnost vyhodnocení výsledků, data byla analyzována pomocí Tématické analýzy, která v této studii vykrystalizovala 2 hlavní strategické přístupy v social sellingu. Tyto přístupy (tzv. Push a Pull strategie) obsahují praktické příklady a konkrétní aktivity, které mohou prodejci využívat v každodenní praxi. Tyto výsledky jsou prezentovány s důrazem na praktičnost a jednoduchost implementace. Tvoří proto hlavní přínos autorovo výzkumu. V poslední části autor zmiňuje výzvy a manažerská doporučení, které mohou obchodníci využít v každodenním pracovním životě.This diploma thesis focuses on social media usage in B2B sales. Based on the systematic literature review conducted by the author, he has found out that recent researchers (Salo, 2017) suggest further research in the area of how and in which sales phase should various social networking sites, technologies and plugins used. To further fill this research gap, author decided to identify these social media and their usage among B2B salespeople in the so-called social selling process. The social selling process in this thesis applies mainly to acquiring new prospects and tangentially to taking care of existing clients (follow-up step). Author has chosen a qualitative research method via conducting 10 in-depth semi-structured interviews to reveal these instruments as well as motivation of a sales person on why to use social media in the selling process. The collected data was analyzed using Thematic analysis to ensure the right procedure and to identify main themes which crystalized into 2 main strategic approaches in social selling. These approaches (Push and Pull) include practical examples of concrete activities which sales people can use in their daily jobs and are presented with focus on practicality and ease of implementation. These also form the main contribution of author`s research. In the last part, author mentions challenges in social selling and recommended managerial implications for salesforce
TeX v jednoduchém unixovém prostředí
summary:Při ladění TeXového dokumentu potřebujeme mnohokrát opakovaně pouštět TeX, podívat se, jak dopadl výsledek v prohlížeči DVI nebo PDF souboru, mrknout na výpis TeXu na terminálu, podívat se případně do logu a celou činnost opakovat. V tomto článku je ukázáno, jak tuto práci dělá autor článku. Proces "editor-TeX-kuk" je zde podporován jednoduchými unixovými nástroji: bashovým skriptem texloop, který si autor pro tyto účely vytvořil, dále terminálem Xterm a jednoduchým editorem, který umí navázat na klávesovou zkratku spuštění příkazu v systému. Čtenář se zde může inspirovat a přizpůsobit tyto nástroje svým vlastním potřebám. V článku je popsána funkce skriptu texloop, dále je neformálně rozveden dlouholetý vývoj autorova vztahu k textovým editorům a konečně je zde uvedena konfigurace terminálu Xterm, aby vyhovoval českému prostředí jak v kódování ISO-8859-2, tak v kódování UTF-8. Pro kódování UTF-8 si v závěru článku vygenerujeme TeXový formát csplain.summary:By debugging a TeX document it is necessary many times repeatedly to run TeX, to look for the result in DVI or PDF file, to gander the TeX output on the terminal, or eventually to have a look in the log-file, and all that action to repeat. In the paper it is show, how this work is made by author. The process '‘'editor-TeX-look' is supported by simple Unix tools: bash script texloop, created by author for these purposes, Xterm terminal and a simple editor, which is able to link to the shortcut key the activation of a system command. The reader could be inspired with the solution and to adapt these tools to his/her own needs. In the paper the function of the texloop script is described, and further the longstanding evolution of the author's relation to text editors is informal elaborated and finally a configuration of Xterm terminal, suitable for the czech environment with both ISO-8859-2 and UTF-8 encoding is introduced. For UTF-8 encoding the TeX format csplain is generated at the end of the paper
Analýza perspektivy vedoucích prodeje na řízení pojišťovacích agentů v etnicky různorodých zastoupeních v Organizaci G, Malajsie.
Cílem této práce je odhalit klíčové faktory a výzvy spojené s řízením etnicky různorodého pojišťovacího zastoupení v oboru životního pojištění v Malajsii. Autor si klade za cíl zkoumat pohled vedoucích prodeje v Organizaci G v Malajsii na jejich způsob řízení agentů. Kombinované kvantitativní a kvalitativní metody budou použity prostřednictvím průzkumu a rozhovorů se 79 agenty a 12 vedoucími prodeje. Odpovědi budou analyzovány za účelem porozumění výzvám, kterým čelí vedoucí prodeje při řízení etnicky různorodého zastoupení, a zkoumat potenciální řešení. Autor navrhuje iniciativy a metody k posílení stylů vedení a zlepšení procesů pro udržení úspěšného zastoupení v kontextu etnické rozmanitosti.The goal of this thesis is to uncover the key factors and challenges in managing an ethnically diverse insurance agency in Malaysia's life insurance industry. The author aims to examine the sales managers' perspective in Organisation G, Malaysia, regarding their expression of managing their agents. Quantitative and qualitative methods will be employed through surveys and interviews among 79 agents and 12 sales managers. The responses will be analysed to understand the challenges sales managers face in managing a multi-ethnic agency and explore potential solutions. The author proposes initiatives and methods to enhance leadership styles and improve the processes for maintaining a successful agency in the context of multi-ethnicity
AUTHOR BOOK
Vytvořil jsem autorskou knihu o čtyřiceti stránkách s ilustracemi a minimem textu. Kniha je černobílá, dominuje v ní tušová kresba štětcem a perem. Kromě té je v knize ale i text, který slouží jako poetické doplnění ilustrací.
Obsah knihy se zaměřuje na úzký kruh přátel a zároveň vypovídá o autorovi jak vybranými motivy, situacemi tak linkou.
Vyznění knihy je spíše pocitové, má zanechat dojem, ne popisně vysvětlovat.ObhájenoI have created author book that has 40 pages with ilustrations and minimum of text. The book is black and white and contains ink drawings. There is also text poetically coresponding with pictures
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