4,630 research outputs found
Stolen City: Racial Capitalism and the Making of Winnipeg
Book review by Simon J. Lambert of Stolen City: Racial Capitalism and the Making of Winnipeg, author Owen Toews
The value proposition of integrative diagnostics for (early) detection of cancer. On behalf of the EFLM interdisciplinary Task and Finish Group “CNAPS/CTC for early detection of cancer”
Disruptive imaging and laboratory technologies can improve clinical decision processes and outcomes in oncology. However, certain obstacles must be overcome before these technologies can be fully implemented as part of the standard for care. An integrative diagnostic approach represents a unique opportunity to unleash the full diagnostic potential and paves the way towards personalized cancer diagnostics. To meet this demand, an interdisciplinary Task Force of the EFLM was initiated as a consequence of an EFLM/ESR during the CELME 2019 meeting in order to evaluate the clinical value of CNAPS/CTC (circulating nucleic acids in plasma and serum/circulating tumor cells) in early detection of cancer. Here, an overview of current disruptive techniques, their clinical implications and potential value of an integrative diagnostic approach is provided. Furthermore, requirements such as the establishment of diagnostic tumor boards, development of adequate software solutions and a change of mindset towards a new generation of diagnosticians providing actionable health information are presented. This development has the potential to elevate the position and clinical recognition of diagnosticians
Simon Winchester, Map that changed the world
reviewThe author, noted writer Simon Winchester (who graduated with a Geology degree from Oxford University), makes no secret of the fact that this text is an unabashed tribute to his hero, William Smith, a nineteenth century surveyor and canal digger whose passionate hobby was geology. In the course of Smith\u27s vocation and avocation he went on to create what became the first geologic map of the British Isles in 1815 and to become the individual who many believe to be the father of modem geology
Protein-induced modifications in crystal morphology of a hydrogen-bonded organic framework
In this work, we studied the encapsulation of a range of proteins in a hydrogen-bonded organic framework (HOF) comprised of a tetraamidinium cation and diazobenzene-based dicarboxylate anion. We explore the use of external stimuli: light and temperature to modulate HOF crystal growth and size. In particular, we found photo-isomerisation can be used to control the concentration of the trans-azobenzene building block that contributes to HOF formation. When HOF growth was slowed sufficiently, deformation of the crystals and ultimately multicrystal aggregates were observed in the presence of some proteins. We propose that the extent of crystal deformation, consistent with better protein association, may be governed by differences in the type and strength of interactions between proteins and the surface of the growing HOF crystals.Kate L. Flint, Jack D. Evans, Francesco Carraro, Simon Renner, Oliver M. Linder-Patton, Heinz Amenitsch, Robert J. Falconer, Nicholas G. White, Christopher J. Sumby, Paolo Falcaro and Christian J. Doona
Profile of route by the Grand Portage and Pigeon River from Lake Superior to Rainy Lake ; Profile of route between Lake Superior and Rainy Lake by the Kaministiquia and Riviere la Seine / [signed] S.J. Dawson, C.E. in charge Red River Expedition. Related titles Related to : Dawson, S.J. (Simon James), 1820-1902. Report on the exploration of the country between Lake Superior and the Red River settlement. (Simon James), 1820-1902. Report on the exploration of the country between Lake Superior and the Red River settlement.
Summary
Elevation profiles of two routes connecting Lake Superior and Rainy Lake in northwestern Ontario, each via a series of waterways and portages.
Notes
Likely detached from: Dawson, S.J. (Simon James), 1820-1902, author. Report on the exploration of the country between Lake Superior and the Red River settlement : and between the latter place and the Assiniboine and Saskatchewan / by S.J. Dawson, Esquire, C.E.
Map theme: Land Use, Land Cover.
Related Work
Dawson, S. J. (Simon James), 1820-1902. Report on the exploration of the country between Lake Superior and the Red River settlement.ColorScale 1:253,440. 4 miles to 1 in. Vertical scale 1:2,400. 200 ft. to 1 in. (W 92°38ʹ--W 89°31ʹ/N 48°31ʹ--N 47°58ʹ).
Scale 1:253,440. 4 miles to 1 in. Vertical scale 1:2,400. 200 ft. to 1 in. (W 92°44ʹ--W 89°11ʹ/N 48°49ʹ--N 48°18ʹ)
Exploiting Domain Knowledge in Making Delegation Decisions
@inproceedings{conf/admi/EmeleNSP11, added-at = {2011-12-19T00:00:00.000+0100}, author = {Emele, Chukwuemeka David and Norman, Timothy J. and Sensoy, Murat and Parsons, Simon}, biburl = {http://www.bibsonomy.org/bibtex/20a08b683088443f1fd36d6ef28bf6615/dblp}, booktitle = {ADMI}, crossref = {conf/admi/2011}, editor = {Cao, Longbing and Bazzan, Ana L. C. and Symeonidis, Andreas L. and Gorodetsky, Vladimir and Weiss, Gerhard and Yu, Philip S.}, ee = {http://dx.doi.org/10.1007/978-3-642-27609-5_9}, interhash = {1d7e7f8554e8bdb3d43c32e02aeabcec}, intrahash = {0a08b683088443f1fd36d6ef28bf6615}, isbn = {978-3-642-27608-8}, keywords = {dblp}, pages = {117-131}, publisher = {Springer}, series = {Lecture Notes in Computer Science}, timestamp = {2011-12-19T00:00:00.000+0100}, title = {Exploiting Domain Knowledge in Making Delegation Decisions.}, url = {http://dblp.uni-trier.de/db/conf/admi/admi2011.html#EmeleNSP11}, volume = 7103, year = 2011
Environmental and Parental Influences on Offspring Health and Growth in Great Tits (Parus major)
PMCID: PMC3728352This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Exciplex fluorescence of {[Zn(bipy)(1.5)(NO3)(2)}]center dot CH3OH center dot 0.5pyrene}n: a coordination polymer containing intercalated pyrene molecules (bipy=4,4 '-bipyridine)
We report the first use of fluorescence spectroscopy to probe the environment of the cavities that are present in open framework coordination polymers.PT: J; CR: BIRADHA K, 1998, CHEM COMMUN, P1327 BODENANT B, 1998, J AM CHEM SOC, V120, P7511 BODENANT B, 1999, J ORG CHEM, V64, P7034 DEDEREN JC, 1981, J PHYS CHEM-US, V85, P1198 FRAIJI LK, 1992, J CHEM EDUC, V69, P424 FUJITA M, 1994, J AM CHEM SOC, V116, P1151 GRIESER F, 1980, J AM CHEM SOC, V102, P7258 HARRIMAN A, 1999, PHYS CHEM CHEM PHYS, V1, P4203 HARTLEY RJ, 1985, J AM CHEM SOC, V107, P3436 KALYANASUNDARAM K, 1977, J AM CHEM SOC, V99, P2039 LOSIER P, 1996, ANGEW CHEM INT EDIT, V35, P2779 MOULTON B, 2001, CHEM REV, V101, P1629 NOSAKA Y, 1981, J PHYS CHEM-US, V85, P1353 SEN K, 2001, J PHYS CHEM A, V105, P9077 SIMON JA, 1997, J AM CHEM SOC, V119, P11012 SOUJANYA T, 2000, J PHYS CHEM A, V104, P9408 WILSON GJ, 1997, J PHYS CHEM A, V101, P4860 WILSON GJ, 1998, J PHYS CHEM A, V102, P5150 ZAWOROTKO MJ, 2001, CHEM COMMUN, P1; NR: 19; TC: 25; J9: CHEM COMMUN; PG: 2; GA: 593NBSource type: Electronic(1
Erratum to:Hospital Admissions due to Dysglycaemia and Prescriptions of Antidiabetic Medications in England and Wales: An Ecological Study (Diabetes Therapy, (2018), 9, 1, (153-163), 10.1007/s13300-017-0349-1)
In the original publication, the fifth author’s name was incorrectly published as Simon J. Bell. The correct name should read as ‘J. Simon Bell’. In the affiliations, the fifth author’s name was incorrectly published as S. J. Bell. The correct name should read as J. S. Bell. In the disclosures, the fifth author’s name was incorrectly published as Simon J. Bell. The correct name should read as ‘J. Simon Bell’. The original article was corrected. Open Access. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/ by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.</p
Forecasting banknotes
A central bank’s liquidity forecast is important in ensuring that it supplies the banking system’s need for central bank money. Banknote (or currency in circulation) demand is the largest and for some central banks the most variable component of the liquidity forecast. Accurate forecasting of banknotes is essential in ensuring an accurate liquidity forecast and in turn effective monetary policy implementation. This Handbook discusses these issues and outlines a structural time series state space (STSSS) model which is now used by central banks including the Bank of England and ECB to forecast banknotes (currency in circulation).Forecasting banknotes
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