32 research outputs found
Nadine Magloire. Romancière séditieuse mal-aimée de la critique littéraire
No full textCet article analyse comment, avec Le sexe mythique (1975), Nadine Magloire aurait contrevenu aux conventions de la bienséance en abordant les sujets épineux de la sexualité et de l’érotisme. Au moyen d’une écriture séditieuse, d’une plume contestataire et d’un style percutant, l’auteure met en scène une héroïne célibataire qui entretient des relations sentimentales avec deux hommes différents et discute ouvertement de la « performance » de ses amants, ainsi que de leurs lacunes sexuelles. Si quelques critiques littéraires considèrent que ce roman illustre adéquatement la condition féminine en Haïti, d’autres, au contraire, estiment qu’il devrait plutôt être taxé de pamphlet inutile et provocateur. En allant résolument à l’encontre des commentaires de la critique, du public et de ses détracteurs, Nadine Magloire a-t-elle anéanti sa propre carrière littéraire ?This article analyzes how, with Le sexe mythique (1975), Nadine Magloire seems to have contravened the conventions of propriety by tackling the thorny subjects of sexuality and eroticism. Using seditious writing, a protesting pen and a hard-hitting style, the author portrays an unmarried heroine who has sentimental relationships with two different men, and openly discusses the “performance” of her lovers, as well as their sexual shortcomings. While some literary critics consider that this novel adequately illustrates the female condition in Haiti, others, on the contrary, feel that it should rather be labeled a useless and provocative pamphlet. By going resolutely against the comments of critics, the public and her detractors, has Nadine Magloire destroyed her own literary career
The Modular Soundscape: Sound as an architectural domain
No full textNoise pollution is a contemporary problem that developed through urbanisation and industrialization. The consequences of this issue directly influence the health of human beings, as their perception of noise leads to certain behavioural responses. By addressing this issue in a strategic way, residential housing can still be created in noise-polluted areas in response to the housing shortage in the Netherlands. By masking noise with pleasurable and healthy sounds, residents' (mental) health can be stimulated in an eco-friendly living environment. This can be done through the placement of noise-free courtyards, selecting a dense and noise-reflecting facade, and creating healthy soundscapes in the courtyards through the integration of vegetation, water and biodiversity. These courtyards function as frames in which nature lets its freedom be heard.Architecture, Urbanism and Building Science
Characterisation of oestrogenic properties of Isoflavones derived from Millettia griffoniana Baill.: - Molecular mode of action and tissue selectivity
No full textSix isoflavones derived from Millettia griffoniana namely, 4’-methoxy-7-O-[(E)-3-methyl-7hydroxymethyl-2,6 octadienyl]isoflavone (7-O-DHF), Griffonianone C (Griff C), 7-O-geranylformononetin (7-O-GF), 3’,4’-dihydroxy-7-O-[(E)-3,7-dimethyl-2,6-octadienyl]isoflavone (7-O-GISO), Griffonianone E (Griff E), 4’-O-geranylisoliquiritigenin (4-O-GIQ) were tested for potential oestrogenic activities in three different oestrogen receptor alpha (ERα) dependent assays, namely a recombinant yeast assay, a reporter gene assay based on stably transfected MCF-7 cells (MVLN cells) and the induction of alkaline phosphatase in Ishikawa cells. The oestrogenic activities of isoflavones from Millettia griffoniana could be completely suppressed by the pure oestrogen antagonist, fulvestrant. The expression of Ki-67, proliferating cell nuclear antigen (PCNA) and cyclin D1 (CD1) mRNA used as indicator of cell proliferation in MCF-7 cells was assayed. Based on these in vitro results, Griff C was further tested in vivo. The main objective of this part of the work was to study the mechanistic basis of the oestrogenicity Three different doses of Griff C (2, 10, or 20 mg/kg BW) of Griff C in ovariectomised Wistar rats. 17β-oestradiol (E2: 10 µg/kg BW) was used as positive control. They were treated daily for three consecutive days and sacrificed 24 hours after receiving the last dose. The whole uterus was removed and weight. Liver and vena cava fragments were also collected and stored together with uteri in liquid nitrogen for subsequent real-time PCR to evaluate the effects of Griff C on the regulation of some relevant oestrogen–responsive genes in the uterus, the liver and the vena cava. The role of Griff C in apoptosis or in cell survival, through mediation of the phosphatidylinositol 3 kinase-Akt (PI3K-Akt) signaling pathway, was also investigated. Western blot analysis revealed that Griff C slightly increased the phosphorylation of Akt at its serine 473 residue. In this work, oestrogenic properties of the isoflavones derived from Millettia griffoniana are described using reporter gene assays and the oestrogen-inducible alkaline phosphatase Ishikawa model for the first time. These in vitro data were verified in vivo showing the regulation of the expression of various relevant oestrogen-responsive genes by Griff C. The spectrum of its activity was clearly similar to that of 17β-oestradiol on uterine hepatic and vena cava tissues of ovariectomised rats except for the proliferative response. However Griff C remained 100 to 1000 times less effective than oestradiol. These findings confirmed that some of the biological effects attributed to Millettia griffoniana are closely related to oestrogen-mediated action
Caracteristicas ecocardiograficas en pacientes con enfermedad cerebral vascular isquemica de repeticion y foramen ovale permeable
No full textThe geology of the Ste. Justine map-area.
No full textFollowing the discovery of copper-nickel mineralization in 1951 at St. Fabien de Panet, Montmagny County, about 50 miles east of Quebec City, the Quebec Department of Mines initiated a program of geological mapping in this area. In 1952, the author assisted Dr. J. Beland in the mapping of the St. Magloire area where the copper-nickel mineralization was discovered. [...
150th anniversary of clinical description of multiple sclerosis
No full textThe clinical features of multiple sclerosis were first defined in detail and with pathologic confirmation in a medical thesis published at the Salpêtrière, Paris, in 1868. The author, Leopold Ordenstein (1835–1902), a German physician, analyzed cases collected by his mentor, Jean-Martin Charcot (1825–1893). The 2 clinician-scientists described the characteristic symptoms, predisposing age, and pathologic features of the disease, and emphasized the clear delineation from other chronic progressive disorders, especially paralysis agitans. The latter was referred to as Parkinson disease by William Sanders in 1865 and adopted by Désiré-Magloire Bourneville on behalf of Charcot in 1875. This essay commemorates the 150th anniversary of the publication of the pioneering work of Leopold Ordenstein and Jean-Martin Charcot.</jats:p
In Vitro Evaluation of the Biocompatibility of a Ni-Cr Alloy (Wiron 88): An Ultrastructural Study
No full textHealth Hazard Evaluation Report: HETA-87-413-1921: Ministry of Health - St. Lucia; St. Lucia, West Indies
No full textIn response to a request from the Ministry of Health of St. Lucia concerning excessive noise exposure for workers in several of the country's industries, technical expertise and equipment from NIOSH were directed toward a project for hearing conservation for workers in that country. One day of noise sampling was conducted at each location in order to maximize the number of locations from which data was collected. The industries sampled included the Winera Box Facility (SIC-2653), the LUCELEC - Vieux Fort (SIC-4911), Belles Fashions (SIC-2342), Tolyn Paper Company (SIC-2647), Heinekin Brewery (SIC-2082), NEHOC Gloves (SIC-2381), Data Delay Devices (SIC- 3674), LUCELEC - Union Station (SIC-4911), N.Y. Daher Tobacco Co. (SIC-2111), Ramco Plastics Co. (SIC-3079), DuBoulay's Bottling Co. (SIC-2086), and the Government's Printery (SIC-2741). Of the 12 industries sampled, six had at least one 8 hour time weighted average noise level measurement which exceeded the U.S. OSHA noise PEL of 90 decibels-A (dB-A). Eleven of the 12 had noise levels exceeding the NIOSH REL of 85 dB-A. The author recommends that personnel from the Ministry of Health return to the 12 factories with excessive noise levels to distribute copies of the findings; that the need for audiometric testing of St. Lucian workers be pursued; that academic programs concerning hearing, auditory anatomy and physiology, and hearing loss be developed in the school system; that employees be informed of the results; that hearing protective devices be made mandatory in noise industries; that LUCELEC be the first industry to receive the hearing conservation program; and that additional unsafe conditions discovered during these surveys also be addressed
