3,783 research outputs found
Five minutes with: Victor Henning, co-founder of Mendeley – Connecting academic research to the outside world
No full textLast week Patrick Dunleavy discussed his experience of transferring his personal research library onto the Mendeley software package. Today Sierra Williams talks to Mendeley co-founder Victor Henning about the company’s new approach to enhancing the impacts and visibility of academic work
Total synthesis of (-)-pyridovericin and synthetic studies towards aetheramide B
No full textIn this thesis, two projects involving the total synthesis of natural products are presented.
The first part gives an overview on neurodegenerative diseases and introduces the
neuritogenic pyridopolyene natural product (–)-pyridovericin. The enantioselective total
synthesis of (–)-pyridovericin is presented. The key steps were an enantioselective,
iridium-catalyzed hydrogenation of an enoate and an E-selective Horner-Wadsworth-
Emmons reaction. The complex pyridopolyene structure was then truncated and the
neuritogenic core structure identified. Truncated natural product analogs were
synthesized and successfully implemented in a neuritogenic surface material.
The second part reviews the current state of research on HIV and AIDS. Our efforts
towards the total synthesis of the recently isolated HIV-inhibitory natural product
aetheramide B are reported. Three advanced building blocks were synthesized
enantioselectively in good yields. The key steps involved the enantioselective
hydrogenation of an enamide to form an amino ester, the diastereoselective alkynylation
of a homobenzylic aldehyde and the enantioselective reduction of a bromoenone. The
building blocks were then successfully coupled to form the macrocyclic depsipeptide
core structure. The macrocyclic core of aetheramide B was then synthesized in a
macrolactonization reaction
Bamberger Orientstudien
No full textDer Band versammelt insgesamt vierzehn Beiträge von Mitgliedern des Instituts für Orientalistik der Otto-Friedrich-Universität Bamberg zu verschiedenen Forschungsthemen. Das Institut umfasst sieben Professuren/Lehrstühle: Allgemeine Sprachwissenschaft (Prof. Dr. Geoffrey Haig), Arabistik (Prof. Lale Behzadi), Iranistik (Prof. Dr. Birgitt Hoffmann), Islamische Kunstgeschichte und Archäologie (Prof. Dr. Lorenz Korn), Islamwissenschaft (Prof. Dr. Patrick Franke), Judaistik (Prof. Dr. Susanne Talabardon) und Turkologie (Prof. Dr. Christoph Herzog).
Bei den Artikeln handelt es sich um Forschungsbeiträge zur Sprachgeographie Ostanatoliens (Geoffrey Haig), der türkischen (Patrick Bartsch), persischen (Roxane Haag-Higuchi) und arabischen (Lale Behzadi) Literatur, der Religionswissenschaft (Patrick Franke, Johannes Rosenbaum, Susanne Talabardon), zu verschiedenen Aspekten der Geschichte des Nahen und Mittleren Ostens (Birgitt Hoffmann, Nana Kharebava, Andreas Wilde, Barbara Henning, Christoph Herzog) sowie zur islamischen Architektur (Lorenz Korn, Mustafa Tupev).This volume brings together fourteen contributions on diverse fields of research by members of the Institute for Near and Middle Eastern Studies of the Otto-Friedrich University, Bamberg. The institute includes seven departments: General Linguistics (Geoffrey Haig), Arabic Studies (Lale Behzadi), Iranian Studies (Birgitt Hoffmann), Islamic Art and Archaeology (Lorenz Korn), Islamic Studies (Patrick Franke), Jewish Studies (Susanne Talabardon) and Turkish Studies (Christoph Herzog).
The contributions to the volume represent original research in the following fields: the linguistic geography of Eastern Anatolia (Geoffrey Haig), Turkish (Patrick Bartsch), Persian (Roxane Haag-Higuchi) and Arabic (Lale Behzadi) literature, aspects of religious studies (Patrick Franke, Johannes Rosenbaum, Susanne Talabardon), Near and Middle Eastern history (Birgitt Hoffmann, Nana Kharebava, Andreas Wilde, Barbara Henning, Christoph Herzog), and Islamic architecture (Lorenz Korn, Mustafa Tupev)
A note from the editors
No full textThe first three papers in this issue are based on a symposium entitled “Rasmussen Revisited 3—Human Factors, Accidents and Error” held at a joint conference in Banff in 2017, organised by the Association of Canadian Ergonomists and by the Organizational Design and Management (ODAM) committee of the International Ergonomics Association. In the words of Patrick Waterson, Jean-Christophe Le Coze and Henning Boje Andersen (1): “The work of Jens Rasmussen over the course of the last half century represents some of the most influential contributions to the fields of cognitive science, human factors, ergonomics and safety science.” These three papers both honour that contribution and show the continued value of applying the theory and tools developed by Jens Rasmussen
The Impact Of The Development Of ICT In Several Hungarian Economic Sectors
No full textAs the author could not find a reassuring mathematical and
statistical method in the literature for studying the effect of
information communication technology on enterprises, the author
suggested a new research and analysis method that he also used to study the Hungarian economic sectors. The question of what
factors have an effect on their net income is vital for enterprises. At first, the author studied some potential indicators related to economic sectors, then those indicators were compared to the net income of the surveyed enterprises. The resulting data showed that the growing penetration of electronic marketplaces contributed to the change of the net income of enterprises to the greatest extent.
Furthermore, among all the potential indicators, it was the only indicator directly influencing the net income of enterprises.
With the help of the compound indicator and the financial data
of the studied economic sectors, the author made an attempt to find a connection between the development level of ICT and
profitability. Profitability and productivity are influenced by a lot of other factors as well. As the effect of the other factors could not be measured, the results – shown in a coordinate system - are not full but informative.
The highest increment of specific Gross Value Added was
produced by the fields of ‘Manufacturing’, ‘Electricity, gas and water supply’, ‘Transport, storage and communication’ and
‘Financial intermediation’. With the exception of ‘Electricity, gas and water supply’, the other economic sectors belong to the group of underdeveloped branches (below 50 percent).
On the other hand, ‘Construction’, ‘Health and social work’ and
‘Hotels and restaurants’ can be seen as laggards, so they got into the lower left part of the coordinate system.
‘Agriculture, hunting and forestry’ can also be classified as a
laggard economic sector, but as the effect of the compound
indicator on the increment of Gross Value Added was less
significant, it can be found in the upper left part of the coordinate system. Drawing a trend line on the points, it can be made clear that it shows a positive gradient, that is, the higher the usage of ICT devices, the higher improvement can be detected in the specific Gross Value Added
La dilution linguistique des responsabilités. Essai de description polyphonique des marqueurs évidentiels il semble que et il parait que
No full textHenning Nølke : « The linguistic dilution of responsibilities. A polyphonic description of the evidential markers il semble que and il parait que »
Assertion guarantees truth based on evidence available to the speaker. The speaker may indicate the source and type of his evidence. This paper deals with the two French evidentials il semble que and il paraît que. Both indicate hearsay evidence and are equivalent to the English evidential it seems that. Although very similar at first glance, closer analysis reveals important, though often rather subtle differences as to the type of evidence. A polyphonic study permits a detailed explication of their functioning, and may explain observable distributional differences.Nølke Henning. La dilution linguistique des responsabilités. Essai de description polyphonique des marqueurs évidentiels il semble que et il parait que. In: Langue française, n°102, 1994. Les sources du savoir et leurs marques linguistiques, sous la direction de Patrick Dendale et Liliane Tasmowski. pp. 84-94
How the EU can move to a higher growth path : some considerations
No full textIn the current slowdown in Europe, the United States and Japan, policy makers are vexed by the question when a recovery will come. This is the wrong question. The issue should be how a higher growth path can be reached in the long run, i.e., how the potential growth rate of our economies can be increased from the supply side. --
Euroland: recovery will slowly gain momentum
No full textEconomic activity in the euro area has weakened since last summer. In the second half of 2002, real GDP increased at an annualized rate of around 1 percent only. Economy-wide capacity utilization has further declined and the situation on labor markets has worsened. The increase in consumer prices has calmed down somewhat after an acceleration at the beginning of last year. Still, the inflation rate remains surprisingly high against the background of weak economic activity that has already lasted for two years. Monetary policy in the euro area is clearly expansionary. With only about 0.5 percent, the real interest rate is currently quite low by historical standards. Moreover, the nominal interest rate is well below the rate implied by the standard Taylor rule, even when low estimates of the current size of the output gap and the equilibrium real interest rate are employed in the calculation of the rule. Still, monetary policy is probably not too expansionary. According to theory, the equilibrium real interest rate may be substantially below the long-run average real interest rate in situations such as the current one with depressed income and profit expectations. However, these considerations also imply that the ECB should bring the real interest rate back towards the long-run average once the depressing factors will have vanished. The situation of public finances in the euro area deteriorated further in the course of last year, with the aggregated budget in the countries of the euro area approaching a deficit of 2.3 percent of GDP in 2002. The cyclically adjusted budget deficit in the euro area was as high as in 1998, the year immediately before the beginning of the third stage of the Economic and Monetary Union. Whereas most countries have in the meantime complied with the goal of the Stability and Growth Pact to at least balance the budget over the medium term, the budget deficit in Germany, France, Italy and Portugal remained high both in actual and in structural terms. The governments of the three largest countries of the euro area are not likely to switch towards a policy of fiscal consolidation based on cuts in primary spending in 2003 and 2004. Moderate wage settlements would be appropriate in the current cyclical situation. However, wage increases have not slowed down over the past year, and are not expected to do so to any meaningful extent this year and next, reflecting the judgment that labor market rigidities will remain significant over the forecast horizon. Nevertheless, as employment is likely to be slow in responding to a recovery in production, the rise in unit labor costs will decelerate considerably, improving the chances that inflation will fall persistently below 2 percent. The leading indicators suggest that economic activity in the euro area will remain weak in the first half of this year. Under the assumption that the war in the Gulf region is of short duration and that the global political situation calms down afterwards, dampening factors from the Iraq conflict are expected to wane. Impulses from expansionary monetary policy will then increasingly take effect and domestic driving forces will gain the upper hand. We expect real GDP to increase by 1.0 percent and by 2.6 percent in 2003 and 2004, respectively. The situation on the labor market will start to improve towards the end of this year only. Inflation will be moderate over the forecast horizon. In 2004, consumer prices will probably rise by 1.9 percent on average, after 2.2 percent this year. --
Numerical experiments for "Error bounds for discrete minimizers of the Ginzburg-Landau energy in the high-κ regime" (v2)
No full textThis program is intended to reproduce the results from the preprint
"Error bounds for discrete minimizers of the Ginzburg–Landau energy in the high- regime"
by Benjamin Dörich and Patrick Henning
The codes generates the lines in Figures2 and 3
#### Requirements
The program is tested with
Ubuntu 20.04.5 LTS and Python 3.8.10 and the following version of its modules:
- numpy - 1.17.4
- scipy - 1.3.3
- matplotlib - 3.1.2
- tikzplotlib - 0.9.8
- dolfin - 2019.2.0.dev0
- fenics - 2019.2.0.dev0
#### Figures
In the folder "code_23_DoerichHenning_GL" open a console and run the following commands after each other (2a+b, 4a+b can be executed in paralell).
1) Run "python3 c1_generate_rectangle.py"
2a) Run "python3 c2a_GL_FEM_comp_all_min_finest.py"
2b) Run "python3 c20_GL_FEM_comp_kappa20.py"
3) Run "python3 c2b_GL_FEM_comp_all_min.py"
4a) Run "python3 c3a_GL_FEM_comp_all_errors.py"
4b) Run "python3 c3b_GL_FEM_comp_all_eigs.py"
5) Run "python3 c4_GL_FEM_draw_error_plot.py"
After running the calculations, the files are stored as follows:
(a) the folder "plots_for_paper" contains the pdf and tikz files for the error plots in Figure 2 and 3.
(b) the folders "sol_ref_3_Mag_st_2.0_kappa_[KAPPA]_P1_square" contain all figures of the solutions where [KAPPA] is replaced by the respective value
Numerical experiments for "Error bounds for discrete minimizers of the Ginzburg--Landau energy in the high- regime"
No full textThis program is intended to reproduce the results from the preprint
"Error bounds for discrete minimizers of the Ginzburg--Landau energy in the high- regime"
by Benjamin Dörich and Patrick Henning
The codes generates the lines in Figure 1
#### Requirements
The program is tested with
Ubuntu 20.04.5 LTS and Python 3.8.10 and the following version of its modules:
- numpy - 1.17.4
- scipy - 1.3.3
- matplotlib - 3.1.2
- tikzplotlib - 0.9.8
- dolfin - 2019.2.0.dev0
- fenics - 2019.2.0.dev0
#### Figures
In the folder "CRC1173_Preprint_2023-11_Codes" open a console and run the following commands after each other (2a-c can be executed in paralell).
1) Run "python3 c1_generate_rectangle.py"
2a) Run "python3 c2_GL_FEM_comp_all_min.py"
2b) Run "python3 c16_GL_FEM_comp_kappa16.py"
2c) Run "python3 c20_GL_FEM_comp_kappa20.py"
3) Run "python3 c3_GL_FEM_comp_all_errors.py"
4) Run "python3 c4_GL_FEM_draw_error_plot.py"
After running the calculations, the files are stored as follows:
(a) the folder "plots_for_paper" contains the pdf and tikz files for the error plots in Figure 1.
(b) the folders "sol_ref_3_Mag_st_2.0_kappa_[KAPPA]_P1_square" contain all figures of the solutions where [KAPPA] is replaced by the respective value
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