902 research outputs found
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The IAAF’s hyperandrogenism regulations suspended
No full textOn 27 July, the Court of Arbitration for Sport (‘CAS’) delivered a landmark ruling on the regulation of gender in sport. The decision explores how the categorisation of sport on the basis of sex can be best reconciled with the “biological reality” that human sex cannot necessarily be divided so clearly. Dr. Seema Patel, Senior Lecturer at Nottingham Trent University, Deputy Director of the Centre for Sports Law and author of ‘Inclusion and Exclusion in Competitive Sport: Socio-Legal and Regulatory Perspectives,’ reviews the case and suggests that sport regulation must be cautious of traditional criteria to determine eligibility in sports
Ceremony - Seema Patel, Nicholas Petrovski, Justin Poh
No full textGraduates Seema Patel, Nicholas Petrovski, and Justin Poh receive their hoods.https://scholarship.kentlaw.iit.edu/commencement_2013/1146/thumbnail.jp
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Striking a balance between inclusion and exclusion in competitive sport
No full textThis thesis aims to investigate the regulatory balance between inclusion and exclusion in competitive sport. Society is obsessed with categorising and treating individuals and groups according to their physical and non-physical differences, such as sex, gender, disability and race. This treatment can lead to the inclusion or exclusion of an individual from the tangible and intangible benefits of society. Where this practice becomes discriminatory, there exists a legal framework in place to protect basic human rights and ensure that people are treated with due respect for their similarities and differences. In a sporting context, the inclusion and exclusion of athletes based upon their differences is often a necessary part of the essence of competitive sporting activity. The protection of the essence involves the establishment of rules and categories that can have an unequal exclusionary impact on certain classes of individual such as some women, transgender, intersex individuals and those with a physical or intellectual disability. The essence of sport also embodies a dominant sporting culture that dictates who is suitable to sport and this can have an exclusionary effect upon particular racial populations
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Olympic sport and gender?
No full textDr Seema Patel reviews the law on gender discrimination in sports law and the Olympic
Jun N-terminal kinase 1 (JNK1) as a molecular target to limit cellular mortality under hypoxia
No full textMany pathological conditions and environmental impacts lead to a decrease in tissue oxygen supply and severe cellular hypoxia. This secondary hypoxia can disturb cellular homeostasis, limiting the efficacy of the prescribed treatment for the primary disease, eventually leading to cellular and organismal death. Jun N-terminal kinase 1 (JNK1) plays a central role in the development of cellular damage under hypoxia, hypoxia/reoxygenation and ischemia/reperfusion conditions. Therefore, we selected JNK1 protein as a molecular target to limit cellular damage and death during hypoxia. The primary objective of this research was to study the influence of the suppression of JNK1 on the development of cellular hypoxic damage. It was hypothesized that suppression of JNK1 will decrease cellular mortality under hypoxia and may increase the efficacy of traditional treatment of many pathological conditions. The hypothesis was verified under both in vitro and in vivo conditions. Another objective was to develop a non-viral system for intracellular delivery of antisense oligonucleotides (ASO) and small interfering RNA (siRNA). ASO and siRNA targeted to JNK1 mRNA delivered by neutral and cationic liposomes, respectively, showed high efficiency in suppressing JNK1 protein. Such suppression limited the caspase dependent apoptosis signaling pathway and decreased cellular mortality induced by severe hypoxia. The results suggest that JNK1 protein might be an attractive target for antihypoxic therapy to increase resistance to many pathological conditions and diseases accompanied by cellular hypoxia.Ph.D.Includes bibliographical references (p. 138-153)by Seema S. Betiger
The Post Office Horizon system and Seema Misra
Get PDFThe author highlights the significance of the Seema Misra case in raising questions about the reliablity of the Post Office Horizon system and more widely suggesting that all digital systems have the possibility of latent defects, and these can never be discounted. He argues that when the efficacy of digital systems is called into question in legal proceedings, the onus of proof must be placed on the supplier of these systems and not the accuser.Index words: Post Office; Horizon; prosecutions; software errors; disclosure Full transcript of the trial Regina v Seema Misra, T2009007 (England & Wales; theft; electronic evidence; Post Office Horizon System; ‘reliability’ of computers) with case commentary and index to original papers held in the Documents Supplement of Volume 12: 2015
Supplemental Material - Tumor treating fields increases blood-brain barrier permeability and relative cerebral blood volume in patients with glioblastoma
No full textSupplemental Material for Tumor treating fields increases blood–brain barrier permeability and relative cerebral blood volume in patients with glioblastoma by Michael Iv, Lewis Naya, Sajal Sanan, Samuel L. Van Buskirk, Seema Nagpal, Reena P. Thomas, Lawrence D. Recht, Chirag B. Patel. The Neuroradiology Journal.</p
An Overview on<i>Citrus aurantium</i>L.: Its Functions as Food Ingredient and Therapeutic Agent
No full textCitrus aurantiumL. (Rutaceae), commonly known as bitter orange, possesses multiple therapeutic potentials. These biological credentials include anticancer, antianxiety, antiobesity, antibacterial, antioxidant, pesticidal, and antidiabetic activities. The essential oil ofC. aurantiumwas reported to display marked pharmacological effects and great variation in chemical composition depending on growing locations but mostly contained limonene, linalool, andβ-myrcene. Phytochemically,C. aurantiumis rich inp-synephrine, an alkaloid, and many health-giving secondary metabolites such as flavonoids. Animal studies have demonstrated a low affinity ofp-synephrine for adrenergic receptors and an even lower affinity in human models. The present review focuses on the different biological activities of theC. aurantiumin animal and human models in the form of extract and its pure secondary metabolites. Finally, it is concluded that both the extract and isolated compounds have no unwanted effects in human at therapeutic doses and, therefore, can confidently be used in various dietary formulations.</jats:p
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Women’s ski jumping and Olympic programme inclusion
No full textA group of female ski jumpers took legal action against the Vancouver Organizing Committee for the 2010 Olympic and Paralympic Winter Games, alleging that its failure to include a women’s ski jumping event amounted to a breach of the Canadian Charter of Rights and Freedoms. Seema Patel, a Lecturer in Sports Law and Management with Nottingham Trent University, examines the International Olympic Committee’s criteria for inclusion in the Olympics, the exceptions that exist for traditional Olympic events and the current status of the appeal
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