862 research outputs found
sj-docx-1-car-10.1177_19476035221144744 – Supplemental material for Getting Cartilage Thickness Measurements Right: A Systematic Inter-Method Comparison Using MRI Data from the Osteoarthritis Initiative
No full textSupplemental material, sj-docx-1-car-10.1177_19476035221144744 for Getting Cartilage Thickness Measurements Right: A Systematic Inter-Method Comparison Using MRI Data from the Osteoarthritis Initiative by Teresa Nolte, Simon Westfechtel, Justus Schock, Matthias Knobe, Torsten Pastor, Elisabeth Pfaehler, Christiane Kuhl, Daniel Truhn and Sven Nebelung in CARTILAGE</p
Entwicklung einer schnellen Pulsformanalyse für asymmetrische AGATA-Germanium-Detektoren
No full textOnTEAM metadata: GDSID: DOC-2007-May-32; Attribute ID: LIBRARY-thesis_diss-2007-005; Title: [GSI Diss 2007-05] Entwicklung einer schnellen Pulsformanalyse für asymmetrische AGATA-Germanium-Detektoren; Author(s): Beck, Torsten; Corporate author(s): ; Publication date: 20070501; Creator: manton; Creation date: 15.05.2007 16:02:12; Change date: 29.10.2008 16:29:34; Access: nur berechtigte Gruppen; Attribute type: Text.Thesis.Diss; Directory path: ['GSI Publications', 'GSI as Publisher']; Attribute path: ['Infrastructure', 'Library and Documentation', 'thesis_diss', 'Added in 2007']; File name(s): ['DOC-2007-May-32-1.pdf']; File title(s): ['']; File access: ['nur berechtigte Gruppen'
Cortical Bone Thickness, Base Osteophyte Occurrence and Radiological Signs of Osteoarthritis in the Fingers of Male Elite Sport Climbers: A Cross-Sectional 10-Year Follow-Up Study
Full text linkBackground: Sport climbing places high mechanical loads on fingers. In 2012, our research group demonstrated adaptations of climbers’ cortical bones with the presence of osteophytes compared to non-climbing controls. Objectives: 1) To investigate 10-year changes in cortical bone thickness, base osteophyte occurrence and radiological signs of osteoarthritis in the fingers of elite male sport climbers with more than 25 years of climbing history and 2) to compare cortical bone thickness, base osteophyte occurrence and radiological signs of osteoarthritis between male sport climbers and age-matched controls at the 10-year follow-up. Methods: All 31 elite sport climbers who participated in both the baseline and 10-year follow-up assessments (follow-up rate 100%) were examined by means of X-rays. Cortical bone thickness, presence of osteophytes and signs of osteoarthritis according to Kellgren-Lawrence were obtained and compared to the baseline values 10 years earlier and to age-matched controls at the follow-up (n = 15). Results: Significantly increased cortical bone thickness over the past 10 years was observed in climbers (mean absolute difference with 95% CI:0.98 mm (0.77 mm, 1.19 mm); p <0.001). Moreover, compared to age-matched controls, climbers had significantly thicker cortical bone at the 10-year follow-up (mean absolute difference with 95% CI:0.86 mm (0.61 mm, 1.12 mm); p <0.001). In climbers, osteophytes and clear signs of osteoarthritis were mainly seen in DIP joints. Signs of osteoarthritis according to Kellgren-Lawrence were more prevalent than 10 years before in most joints. In lateral radiographs, base osteophytes were not significantly more prevalent than 10 years before in most of the joints. The percentage of climbers who had osteophytes in any DIP (PIP) joint increased from 93.5% (67.7%) at baseline to 100% (74.2%) at the 10-year follow-up. The percentage of climbers who had clear signs of osteoarthritis according to Kellgren-Lawrence in any DIP (PIP) joint increased from 12.9% (9.7%) at baseline to 74.2% (64.5%) at 10-year follow-up. Only a few such degenerative changes were found in age-matched controls. Conclusion: An accumulation of repetitive climbing-related stress to the fingers of elite sport climbers over the career may induce lifelong mechano-adaptation of the cortical bone thickness of all phalanges. At the 10-year follow-up, a further significant increase in radiographic signs of osteoarthritic changes was observed
Manifolds, sheaves, and cohomology
No full textThis book explains techniques that are essential in almost all branches of modern geometry such as algebraic geometry, complex geometry, or non-archimedian geometry. It uses the most accessible case, real and complex manifolds, as a model. The author especially emphasizes the difference between local and global questions. Cohomology theory of sheaves is introduced and its usage is illustrated by many examples. Content Topological Preliminaries - Algebraic Topological Preliminaries - Sheaves - Manifolds - Local Theory of Manifolds - Lie Groups - Torsors and Non-abelian Cech Cohomology - Bundles - Soft Sheaves - Cohomology of Complexes of Sheaves - Cohomology of Sheaves of Locally Constant Functions - Appendix: Basic Topology, The Language of Categories, Basic Algebra, Homological Algebra, Local Analysis Readership Graduate Students in Mathematics / Master of Science in Mathematics About the Author Prof. Dr. Torsten Wedhorn, Department of Mathematics, Technische Universität Darmstadt, Germany
James Watson, Maclyn McCarty, and Torsten Wiesel
Full text linkTorsten Wiesel (right) with Professor Emeritus Maclyn McCarty (center), co-author of the paper with Oswald Avery and Colin MacLeod, and James D. Watson, director of Cold Spring Harbor Laboratory, 1994
Photo by Leif Carlsson
To commemorate the fiftieth anniversary of the discovery at The Rockefeller University that genes are made of DNA - considered by many to be the single most important biological discovery of the twentieth century - the university has kicked off a year-long series of events that were running through May 1994. The celebration was formally inaugurated in November 1993 with a lecture by Nobel laureate James D. Watson, best known for discovering the double-helical structure of DNA.
See also Search Winter 1994, vol. 4, no. 1https://digitalcommons.rockefeller.edu/group-portraits/1013/thumbnail.jp
Seltsame Schauspiele. Torsten Fogelqvists Deutschlandreise 1934
No full textIn 1934 Torsten Fogelqvist, a prominent member of the Swedish Academy and a well-known journalist and intellectual, visits Nazi Germany. He writes about his visit to the Third Reich in 17 articles published in the Stockholm daily newspaper Dagens Nyheter. The author, highly critical of the Hitler regime, scrutinizes several aspects of the nazified German society such as the attempts to re-educate the German citizen in accordance with the ideology of the new regime, the hero cult in the Nazi movement, and the relationship between the German state and the churches. In order to further an understanding of political and social developments in Germany Fogelqvist uses a specific strategy. He “translates” them into an imaginary Swedish context. This paper compares his views with those of other Swedish visitors
PISM glacial cycle sensitivity experiments of the Antarctic Ice Sheet
No full textThis dataset contains PISM simulation results (http://www.pism-docs.org) of the Antarctic Ice Sheet based on code release v1.0-paleo-ensemble (https://doi.org/10.5281/zenodo.3574033). PISM is the open-source Parallel Ice Sheet Model developed mainly at UAF, USA and PIK, Germany.
With the help of added python scripts, all figures can be reproduced as in the journal publication:
- Albrecht et al., 2020, doi:10.5194/tc-14-599-2020.
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Data:
Find PISM results as netCDF data. See 'README.md' for a list of all performed experiment.
All forcing input data for the experiments and plots can be downloaded and remapped via https://github.com/pism/pism-ais. Some of the original input data files are freely available, for others please contact the author or the corresponding data publisher.
Figure plotting scripts (jupyter notebook based on python, see https://jupyter.org) in 'plot_scripts' access the uploaded PISM results in 'model_data' and save the plots to 'final_figures'. Jupyter notebook can be run in the browser and shared, see https://nbviewer.jupyter.org/url/www.pik-potsdam.de/~albrecht/notebooks/paleo_paper/paleo_paper_final.ipynb.
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Contact:
Albrecht, Torsten ([email protected]) ; Potsdam-Institute for Climate Impact Research (PIK), Potsdam, German
Optimizing Subtalar Arthrodesis: A Human Cadaveric Evaluation of a Novel Partially-Threaded Screw Combination in the Delta Configuration
No full textBackground and Objectives: Despite the established role of subtalar joint arthrodesis (SJA) for treatment of subtalar osteoarthritis, achieving bone union remains challenging, with up to 46% non-union rates. Adequate compression and stable fixation are crucial for successful outcomes, with internal screw fixation being the gold standard for SJA. The delta configuration, featuring highly divergent screws, offers stability, however, it can result in hardware irritation in 20–30% of patients. Solutions to solve this complication include cannulated compression screw (CCS) countersinking or cannulated compression headless screw (CCHS) application. The aim of this biomechanical study was to investigate the stability of a delta configuration for SJA utilizing either a combination of a posterior CCHS and an anterior CCS or a standard two-CCS combination. Materials and Methods: Twelve paired human cadaveric lower legs were assigned pairwise to two groups for SJA using either two CCSs (Group 1) or one posterior CCHS and one anterior CCS (Group 2). All specimens were tested under progressively increasing cyclic loading to failure, with monitoring of the talocalcaneal movements via motion tracking. Results: Initial stiffness did not differ significantly between the groups, p = 0.949. Talocalcaneal movements in terms of varus–valgus deformation and internal–external rotation were significantly bigger in Group 1 versus Group 2, p ≤ 0.026. Number of cycles until reaching 5° varus–valgus deformation was significantly higher in Group 2 versus Group 1, p = 0.029. Conclusions: A delta-configuration SJA utilizing a posterior CCHS and an anterior CCS is biomechanically superior versus a standard configuration with two CCSs. Clinically, the use of a posterior CCHS could prevent protrusion of the hardware in the heel, while an anterior CCS could facilitate less surgical time and thus less complication rates
Die Erfolgsfaktoren für unternehmerisches E-Mail-Marketing nach Dr. Torsten Schwarz am Praxisbeispiel ERGOTOPIA GmbH
Full text linkThis scientific document reveals the results of an empirical examination within the realm of entrepreneurial e-mail-marketing which is based on a literature review by technical author Dr. Torsten Schwarz. Using the start-up company ERGOTOPIA as a practical example, the author of the master thesis investigates whether the explanations of Dr. Schwarz match with the practical implementation of ERGOTOPIA.
Precisely, the scientific paper focuses on the examination of the four aspects lead generation, newsletter-design, software-requirements and performance measurement through monitoring with regard to successful realization of e-mail-marketing campaigns. The empirical part of this examination is made of the introduction as well as the analysis of two conducted so called split-tests that compare specific aspects of the newsletter-design and measure data-driven results to show which kind of aspect produced the more successful campaign.
This way the author proves whether the recommendations by Dr. Schwarz are practically relevant for the company ERGOTOPIA
Long-term evolution of cartilage abnormalities and osteophytes in the fingers of elite sport climbers: A cross-sectional 10-year follow-up study.
No full textThe sequelae of high mechanical stress to the proximal interphalangeal (PIP) and distal interphalangeal (DIP) joints of the fingers in elite sport climbers and its contribution to the development of osteoarthritis are still relatively unknown. The purpose of this study was to investigate the evolution of cartilage abnormalities of the PIP and DIP joints, as well as the progress of osteophytes, in the fingers of elite sport climbers with a minimum of 25 years of climbing history over the time period of the last 10 years. Moreover, their actual cartilage abnormalities and osteophyte occurrence were compared to non-climbing age-matched controls. Thirty-one elite male sport climbers and 15 male non-climbers underwent a sonographic examination of the PIP and DIP joint cartilage and osteophyte thickness in the frontal and sagittal plane of digits II-V of both hands. The same cohort had already been measured with an identical protocol 10 years earlier (follow-up rate of 100%). Compared to the baseline assessment 10 years earlier, the cartilage thickness of sport climbers has significantly decreased; however, it was still greater than in age-matched controls. Moreover, sport climbers showed significantly higher relative frequencies of osteophyte occurrence than non-climbers (all fingers and joints). Nevertheless, despite a substantial (and compared to baseline a further increased) occurrence of osteophytes in elite sport climbers, there was no association between the radiological signs of osteoarthritis and pain within the last six months prior the follow-up investigation.Highlights Long-term elite climbers show thicker cartilage and occurrence of Osteophytes in their fingers (especially Digit III) compared to controls already early in their career.Later occurrence of osteophytes increases (especially Digit II and IV) and cartilage decreases but is still thicker compared to controls. No association between those findings and pain was found
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