1,721,039 research outputs found
Erbium: yttrium-aluminum-garnet laser stapedotomy--a safe technique
No full textOBJECTIVE:
To standardize the technical parameters of the erbium: yttrium-aluminum-garnet (Er:YAG) laser stapedotomy.
STUDY DESIGN:
Retrospective study of all patients with otosclerosis who underwent stapedotomy from January 2002 to January 2006.
SUBJECTS AND METHODS:
The charts of 152 consecutive patients who underwent stapedotomy were reviewed. The patients were stratified into two groups, according to the instrument used. Stapedotomies were performed in group A, with the OPMI TwinEr:YAG laser; and in group B with manual microperforators.
RESULTS:
No statistically significant differences were found over all measured frequencies, between pre- and postoperative bone conduction thresholds, in each group. At the last postoperative follow-up, vertigo and nystagmus were not detected; two patients in group A and one patient in group B showed persistent tinnitus.
CONCLUSION:
Er:YAG laser stapedotomy is a safe and effective procedure, with no damage of the inner ear when strict adherence to the safety parameters is observed. The Er:YAG laser is definitively suitable for stapes surgery, and represents a useful and safe tool in the armamentarium of otological microsurgery
Erbium: yttrium-aluminum-garnet laser stapedotomy--a safe technique
No full textOBJECTIVE:
To standardize the technical parameters of the erbium: yttrium-aluminum-garnet (Er:YAG) laser stapedotomy.
STUDY DESIGN:
Retrospective study of all patients with otosclerosis who underwent stapedotomy from January 2002 to January 2006.
SUBJECTS AND METHODS:
The charts of 152 consecutive patients who underwent stapedotomy were reviewed. The patients were stratified into two groups, according to the instrument used. Stapedotomies were performed in group A, with the OPMI TwinEr:YAG laser; and in group B with manual microperforators.
RESULTS:
No statistically significant differences were found over all measured frequencies, between pre- and postoperative bone conduction thresholds, in each group. At the last postoperative follow-up, vertigo and nystagmus were not detected; two patients in group A and one patient in group B showed persistent tinnitus.
CONCLUSION:
Er:YAG laser stapedotomy is a safe and effective procedure, with no damage of the inner ear when strict adherence to the safety parameters is observed. The Er:YAG laser is definitively suitable for stapes surgery, and represents a useful and safe tool in the armamentarium of otological microsurgery
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Response to “Commentary on Periprosthetic Leakage in Tracheoesophageal Prosthesis: Proposal of a Standardized Therapeutic Algorithm”
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
EX VIVO GENE THERAPY USING AUTOLOGOUS DERMAL FIBROBLASTS EXPRESSING hLMP3 FOR RAT MANDIBULAR BONE REGENERATION
No full textBACKGROUND: Implantation of autologous skin fibroblasts transduced ex vivo with a replication-defective adenoviral vector, carrying the LIM mineralization protein-3 (Ad-LMP-3), and adsorbed on a hydroxyapatite/collagen (HA/COL) scaffold.
METHODS: Twenty-seven Wistar rats were used. A 5- x 5-mm full-thickness defect was created in the exposed mandible. All animals were randomized into 3 experimental groups: (1) autologous dermal fibroblasts transduced with Ad-LMP-3 and adsorbed on the HA/COL; (2) nontransduced dermal fibroblasts adsorbed on the HA/COL scaffold; and (3) HA/COL scaffold without cells. Three-dimensional micro-CT (3DmicroCT or 3DmuCT) and histological analysis were performed.
RESULTS: Efficient neoosteogenesis was observed in animals treated with LMP-3-expressing cells (group 1) as soon as 4 weeks after surgery. Conversely, nonsignificant bone formation was detected in control animals (groups 2 and 3) at all time points tested.
CONCLUSION: These results suggest that the experimental approach based on transplantation of genetically modified autologous cells could provide an alternative treatment for cranio-maxillo-facial defects. Nonetheless, additional data from the study on larger bone defects must follow to foresee a clinical application in the near future
- …
