161,331 research outputs found
Alberto Parolini
No full textBotanico: Parolini, Alberto (1788-1867).
Botanico-viaggiatore in Sicilia, Grecia, Asia minore, raccoglitore della flora Veneta e corrispondente di Bertoloni e Parlatore.
Titolo ed estremi cronologici riportati manoscritti sul recto, dove compare anche la nota: Da: Visiani, Biogr. di Parolini, 1867.
1 fotografia : albumina ; 135 x 92 mm.
Vai alla scheda bibliografica: https://galileodiscovery.unipd.it/discovery/fulldisplay?context=L&vid=39UPD_INST:VU1&search_scope=MyInst_and_CI&tab=Everything&docid=alma99001597809020604
The Immunomodulatory Features of Mesenchymal Stromal Cells Derived from Wharton’s Jelly, Amniotic Membrane, and Chorionic Villi In Vitro and In Vivo Data
No full textThis chapter focuses on the immunomodulatory properties of placental mesenchymal stromal cells (MSCs) derived from the amniotic membrane, umbilical cord, and chorionic villi. Within the amniotic membrane (AM), we discuss the immunomodulatory properties of the two main cell populations that can be isolated from AM: human amniotic mesenchymal stromal cells (hAMSCs) and human amniotic epithelial cells (hAECs). Within the umbilical cord, several compartments have been described, including the amniotic compartment, the Wharton’s jelly (WJ) compartment, and the vascular and perivascular compartment, but herein attention is focused on the properties of human WJ MSCs (hWJMSCs). Since different isolation protocols have been
used, umbilical cord matrix stem cells, umbilical cord stromal cells, and human umbilical cord MSCs (herein hUCMSCs) were also included. This chapter also discusses the properties of human chorionic villi/placenta MSCs (hCVMSCs/hPLMSCs). The nomenclature of placental MSCs used in this chapter was chosen on the basis of consensus from the First International Workshop on Placenta-Derived Stem Cells for hAECs and hAMSCs (Parolini et al. 2008). Since different nomenclature is reported for the other placental MSCs, the following nomenclature is used: hWJMSCs/hUCMSCs for MSCs from WJ (and from umbilical cord where described isolation protocols include WJ) and hCVMSCs/hPLMSCs for MSCs from chorionic villi and the placenta/trophoblast compartment
The Use of Placenta-Derived Cells in Autoimmune Disorders
No full textInterest in the human term placenta has increased in recent years, due mainly to its noninvasive procurement and large cell supply. In addition, cells isolated from different placental tissues share basic properties with other stem cells. Furthermore,the innate immunomodulatory and immunosuppressive functions of placental cells, and the limited expression of human leukocyte antigen (HLA) and costimulatory molecules that allow them to be used across HLA barriers, have made them unique with respect to their conventional counterparts. This chapter discusses the therapeutic potential of placental cells in autoimmune diseases. The chapter begins with a general overview of the pathogenesis and the aberrant immune mechanisms in autoimmune diseases, and then discusses the relevance of placental cells in the scenario of abnormal immune processes, such as those underlying autoimmune diseases
Lettera da Parolini a Visiani
No full textFa parte della corrispondenza ricevuta da Roberto de Visiani e conservata presso la Biblioteca dell\u27Orto Botanico dell\u27Università di Padova
Lettera da Parolini a Visiani
No full textFa parte della corrispondenza ricevuta da Roberto de Visiani e conservata presso la Biblioteca dell\u27Orto Botanico dell\u27Università di Padova
In the puddle of water a star rots: the poetry of Orlando Parolini
No full textA presente tese tem dois objetivos: o primeiro, formar um arquivo da obra poética de Orlando Parolini, obra esta que permaneceu inédita durante quase cinco décadas; o segundo, fazer uma leitura crítica dessa obra através de alguns de seus característicos principais e suas relações com a contracultura. A obra de Parolini é construída num período tenso da história do Brasil e cruza as décadas de 1950, 1960 e 1970. As transformações no país são muitas e intensas, tanto no campo da cultura, quanto no campo político-social. Essas circunstâncias histórias vão passar pela poética anárquica e experimental de Parolini. O experimento formal conjugado com o experimento existencial, ambos sob o signo da rebelião.The present thesis has two objectives: first, to create an archive of Orlando Parolini\'s poetic works, which have remained unpublished for almost five decades; the second, to do a critical reading of these works by way of some of its main features, and its relations with counterculture. Parolinis works were built in a tense period of Brazilian history and cross the 1950s, 1960s and 1970s. The transformations in the country, then, were many and intense, both in the field of culture and in the political-social field. These historical circumstances will go through the anarchic and experimental poetics of Parolini: the formal experiment combined with the existential experiment, both under the sign of rebellion
From fetal development and beyond: a continued role for placenta in sustaining life?
No full textnot availabl
The genomic structure of human BTK, the defective gene in X-linked agammaglobulinemia
No full textIt has recently been demonstrated that mutations in the gene for Bruton's tyrosine kinase (BTK) are responsible for X-linked agammaglobulinemia. Southern blot analysis and sequencing of cDNA were used to document deletions, insertions, and single base pair substitutions. To facilitate analysis of BTK regulation and to permit the development of assays that could be used to screen genomic DNA for mutations in BTK, we determined the genomic organization of this gene. Subcloning of a cosmid and a yeast artificial chromosome showed that BTK is divided into 19 exons spanning 37 kilobases of genomic DNA. Analysis of the region 5' to the first untranslated exon revealed no consensus TATAA or CAAT boxes; however, three retinoic acid binding sites were identified in this region. Comparison of the structure of BTK with that of other nonreceptor tyrosine kinases, including SRC, FES, and CSK, demonstrated a lack of conservation of exon borders. Information obtained in this study will contribute to our understanding of the evolution of nonreceptor tyrosine kinases. It will also be useful in diagnostic studies, including carrier detection, and in studies directed towards gene therapy or gene replacement
How far are we from the clinical use of placental-derived mesenchymal stem cells?
No full textIn recent years, multiple studies have investigated the biology and clinical applications of mesenchymal stem cells (MSCs), trying to define their markers, and elucidate their effects in animal models. MSCs are available from different tissues, and the use of placental-derived MSCs (PMSCs) for treating a variety of disorders is on the forefront. Herein, we discuss the most recent findings regarding the standardization of their isolation procedure and phenotype, along with advantages and limitations of their use. We also discuss the safety of the placental cell products, including the issue of senescence and mutagenesis of PMSCs, and efficacy from preclinical studies
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