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Lettera da Parolini a Visiani
No full textFa parte della corrispondenza ricevuta da Roberto de Visiani e conservata presso la Biblioteca dell\u27Orto Botanico dell\u27Università di Padova
Lettera da Parolini a Visiani
No full textFa parte della corrispondenza ricevuta da Roberto de Visiani e conservata presso la Biblioteca dell\u27Orto Botanico dell\u27Università di Padova
From fetal development and beyond: a continued role for placenta in sustaining life?
No full textnot availabl
Meeting report of the first conference of the International Placenta Stem Cell Society (IPLASS).
No full textThe International Placenta Stem Cell Society (IPLASS) was founded in June 2010. Its goal is to serve as a network for advancing research and clinical applications of stem/progenitor cells isolated from human term placental tissues, including the amnio-chorionic fetal membranes and Wharton's jelly. The commitment of the Society to champion placenta as a stem cell source was realized with the inaugural meeting of IPLASS held in Brescia, Italy, in October 2010. Officially designated as an EMBO-endorsed scientific activity, international experts in the field gathered for a 3-day meeting, which commenced with "Meet with the experts" sessions, IPLASS member and board meetings, and welcome remarks by Dr. Ornella Parolini, President of IPLASS. The evening's highlight was a keynote plenary lecture by Dr. Diana Bianchi. The subsequent scientific program consisted of morning and afternoon oral and poster presentations, followed by social events. Both provided many opportunities for intellectual exchange among the 120 multi-national participants. This allowed a methodical and deliberate evaluation of the status of placental cells in research in regenerative and reparative medicine. The meeting concluded with Dr. Parolini summarizing the meeting's highlights. This further prepared the fertile ground on which to build the promising potential of placental cell research. The second IPLASS meeting will take place in September 2012 in Vienna, Austria. This meeting report summarizes the thought-provoking lectures delivered at the first meeting of IPLASS
Adverse effects induced by ecgonine methyl ester to the zebra mussel: A comparison with the benzoylecgonine
No full textCocaine and its metabolites are the prevalent psychotropic substances in aquatic environment. However, to date the knowledge on their adverse effects to non-target organisms is inadequate. The aims of this study were to investigate sub-lethal effects induced by the ecgonine methyl ester (EME) to the freshwater bivalve Dreissena polymorpha and to compare its toxicity to that by benzoylecgonine (BE), the other main cocaine metabolite. EME sub-lethal effects were investigated by 14 days in-vivo exposures and a multi-biomarker approach. Slight variations in biomarker responses were found at 0.15 μg/L treatment. 0.5 μg/L EME treatment induced destabilization of lysosome membranes, an overall inactivation of defense enzymes, increases in lipid peroxidation, protein carbonylation and DNA fragmentation, but no variations in fixed genetic damage. The use of a biomarker response index (BRI) showed that at 0.5 μg/L both cocaine metabolites had the same toxicity to zebra mussels specimens
Sub-lethal effects induced by a mixture of three non-steroidal anti-inflammatory drugs (NSAIDs) on the freshwater bivalve Dreissena polymorpha
No full textNon-steroidal anti-inflammatory drugs (NSAIDs) are the sixth top-selling drugs worldwide and are commonly found in freshwater ecosystems in the high ng/l to low mu g/l range. Recent studies have investigated both the acute and the chronic toxicity of single NSAIDs on different biological models, but these studies have completely neglected the fact that, in the environment, non-target organisms are exposed to mixtures of drugs that have unforeseeable toxicological behavior. This work investigated the sub-lethal effects induced by a mixture of three common NSAIDs, namely, diclofenac, ibuprofen and paracetamol, on the freshwater bivalve, the zebra mussel (Dreissena polymorpha). The mussels were exposed to three different environmental concentrations of the mixture (Low, Mid and High). A multi-biomarker approach was used to highlight cyto-genotoxic effects and the imbalance of the oxidative status of the treated specimens. The Neutral Red Retention Assay (NRRA) was used as a biomarker of cytotoxicity, whereas the activities of catalase, superoxide dismutase, glutathione peroxidase and glutathione S-transferase were measured to assess the role played by the oxidative stress enzymes. In addition, the single cell gel electrophoresis assay, the DNA Diffusion assay and the micronucleus test were used to investigate possible genotoxic effects. According to our NRRA results, each treatment was able to induce a significant cellular stress in bivalves, probably due to the raise of oxidative stress, as indicated by the alteration of enzyme activities measured in treated specimens. Moreover, the mixture induced significant enhancements of DNA fragmentation, which preluded fixed genetic damage, as highlighted by the increase of both apoptotic and micronucleated cells
In the puddle of water a star rots: the poetry of Orlando Parolini
No full textA presente tese tem dois objetivos: o primeiro, formar um arquivo da obra poética de Orlando Parolini, obra esta que permaneceu inédita durante quase cinco décadas; o segundo, fazer uma leitura crítica dessa obra através de alguns de seus característicos principais e suas relações com a contracultura. A obra de Parolini é construída num período tenso da história do Brasil e cruza as décadas de 1950, 1960 e 1970. As transformações no país são muitas e intensas, tanto no campo da cultura, quanto no campo político-social. Essas circunstâncias histórias vão passar pela poética anárquica e experimental de Parolini. O experimento formal conjugado com o experimento existencial, ambos sob o signo da rebelião.The present thesis has two objectives: first, to create an archive of Orlando Parolini\'s poetic works, which have remained unpublished for almost five decades; the second, to do a critical reading of these works by way of some of its main features, and its relations with counterculture. Parolinis works were built in a tense period of Brazilian history and cross the 1950s, 1960s and 1970s. The transformations in the country, then, were many and intense, both in the field of culture and in the political-social field. These historical circumstances will go through the anarchic and experimental poetics of Parolini: the formal experiment combined with the existential experiment, both under the sign of rebellion
Lettera da Parolini a Visiani (1 marzo 1851)
No full textFa parte della corrispondenza ricevuta da Roberto de Visiani e conservata presso la Biblioteca dell\u27Orto Botanico dell\u27Università di Padova
Editorial: MSC-Derived Extracellular Vesicles and Secreted Factors as “Cell-Free” Therapeutic Alternatives in Regenerative Medicine
No full textNo abstract availabl
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