1,721,106 research outputs found

    Le fonti del federalismo fiscale: una comparazione Italia-Austria

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    La tematica del federalismo fiscale viene affrontata sotto il profilo formale delle fonti del diritto che reggono i relativi assetti finanziari. Vengono in particolare messe in luce le peculiarità dei percorsi normativi intrapresi in Italia e in Austria, ordinamenti che in materia finanziaria innestano elementi di rottura in un quadro di continuità. L'analisi si concentra sia sul livello nazionale/federale, che su quello substatale

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Amino acids are compatible osmolytes for volume recovery after hypertonic shrinkage in vascular endothelial cells

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    The response to chronic hypertonic stress has been studied in human endothelial cells derived from saphenous veins. In complete growth medium the full recovery of cell volume requires several hours and is neither associated with an increase in cell K+ nor hindered by bumetanide but depends on an increased intracellular pool of amino acids. The highest increase is exhibited by neutral amino acid substrates of transport system A, such as glutamine and proline, and by the anionic amino acid glutamate. Transport system A is markedly stimulated on hypertonic stress, with an increase in activity roughly proportional to the extent and the duration of the osmotic shrinkage. Cycloheximide prevents the increase in transport activity of system A and the recovery of cell volume. It is concluded that human endothelial cells counteract hypertonic stress through the stimulation of transport system A and the consequent expansion of the intracellular amino acid pool

    Reply to Letter to the Editor re : Long-term outcome after inflammatory abdominal aortic aneurysm repair: case-matched study.

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    We appreciated the interest raised by our article [1] about inflammatory abdominal aortic aneurysms (AAA), as well as the letter of Dr. Tambyraja, who poses three main questions about the contents of our paper. An increased predisposition to graft-related complications in patients submitted to inflammatory AAA repair has not yet been clearly demonstrated either in previous studies or in the abstract published by Tambyraja et al [2]. Certainly definitive statements about the post-surgical long-term results or complications of this uncommon disease should be made cautiously. Nevertheless, although patient survival is the ideal goal to achieve and assess, a thorough evaluation of the fate of the aortic graft should be taken into account to define the true impact of the surgical treatment in this category of patients. In an era of worldwide applied technologies, the simple, yet accurate, clinical evaluation might be imprecise. Postoperative (short- and long-term) graft and aortic features need an instrumental examination (preferably a computerized tomographic [CT] scan) if they are to be evaluated properly. Indeed, in the article by Lindbald et al. [3], only 35/87 (40%) patients who survived surgical repair were submitted to instrumental follow-up (CT, ultrasound [US], urography), and in Niteckis series, 19/29 (66%) had a CT scan or US [4]. Similarly, no mention of postoperative investigations was made by Tambyraja and colleagues [2]. The need for a more detailed instrumental follow-up was well emphasized by Kalman et al [5], who showed a relatively high rate of vascular and graft abnormalities in the post-surgical period, discovered by CT scan, though clinically silent. Graft infections (demonstrated by cultures) were definitely not found in our study, even in the one patient who developed a prosthetic duodenal fistula. In fact, the fistula was observed 3 years after the second repair of an aneurysm involving the aorta at the previous suture line, a repair that was carried out more than 60 months after the first operation. In any case, the absence of proved infections would not be surprising, considering that the mechanism(s) of paraanastomotic aneurysms after inflammatory AAA repair might not be simply related to an infection but also to ischemic and nutritional damage to the aortic wall in this particular disease. Contamination of the graft consequent to the duodenal dissection as the only cause of paraanastomotic aneurysm seems unlikely. Regarding the percentages we reported from Lindblad et al. [3] and Nitecki et al. [4], we related them only to the patients instrumentally (and not simply clinically) evaluated during the follow-up, i. e., 3/35 (8.5%) for Niteckis patients [4] and 1/19 (5.2%) for Lindblads group [3]. Finally, the graft diameter we used for the repair in patients who showed paraanastomotic aneurysms was 20 mm, thus making unreliable the suggestion that the proximal anastomosis was performed below the aneurysmal aortic neck. In conclusion, although we agree about the relatively small sample size (18 patients) of inflammatory AAA, which however was compared with a matched control group of 54 patients (3 ×), we would like to emphasize that the message of our article was mainly to point out the need for accurate instrumental follow-up of repaired inflammatory AAA. Actually the peculiar characteristics of this disease might well predispose to graft and anastomosis alterations, which, in our opinion, should be more precisely assessed by a CT scan than by a clinical evaluation, which in terms of crude survival, is probably deceptive

    La traiettoria comparata del federalismo fiscale: alcune evidenze dai casi italiano e spagnolo

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    Analisi comparata delle relazioni finanziarie tra i livelli di governo in Italia e in Spagna, a dici anni dalle riforme (solo parzialmente attuate) introdotte nel 2009 nei due ordinament

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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