1,720,957 research outputs found
Quality of oral health in patients with systemic sclerosis
No full textUvod: SSc je rijetka autoimuna bolest obilježena ekcesivnom fibrozom tkiva. Zbog fibroze žlijezda slinovnica i atrofije acinusa dolazi do smanjenog lučenja sline. Snižene pH-vrijednosti sline i promjene oralne mikrobijalne flore povećavaju rizik razvoja zubnog karijesa što se odražava na sveukupno oralno zdravlje.
Cilj: Istražiti odnos sveukupne, nestimulirane i stimulirane sline i pH-vrijednosti sline i kvalitete oralnog zdravlja u bolesnika koji boluju od SSc-a bez pridruženog SS-a ili autoprotutijela vezanih za SS. Ispitati postoji li korelacija između kvaliteta oralnog zdravlja, težine bolesti i kožne zahvaćenosti u ovih bolesnika.
Metode: U istraživanju je sudjelovao 31 bolesnik sa SSc-om, od kojih je 90% imalo difuzni oblik, te 31 kontrolni ispitanik bez SSc-a. Ovo presječno istraživanje provodilo se od kolovoza 2015. do veljače 2017. godine. Svi su ispitanici ispunjavali kriterije Američkog koledža za reumatologiju (American College of Rheumatology) za dijagnozu SSc-a. Stanje oralnog zdravlja određivano je stomatološkim pregledom usne šupljine. Istraživan je QS, QSS, pH-vrijednost sline, KEP, parodontalni status i međučeljusni razmak. Kvaliteta života ispitivana je pomoću upitnika OHIP49. Težina bolesti procijenjena je na osnovi tzv. modificiranog Medsger score, a zahvaćenost kože modificiranim Rodnanovim kožnim testom. Stupanj obrazovanja koristio se kao zamjenska mjera SES-a. Podaci su obrađeni za normalnost distribucije podataka Shapiro-Wilkovim testom. Skupine su se uspoređivale pomoću Studentova t-testa ili Mann-Whitneyjeva testa. Razlike između kontrolne skupine i bolesnika koji su bolovali od SSc-a testirale su se jednosmjernom analizom varijance, odnosno Kruscal-Walisovim testom za neparametrijske podatke. Korelacije između varijabli testirale su se pomoću Pearsonova testa, odnosno Spearmanova testa za neparametrijske varijable, p<0,05 smatrao se statistički značajnim.
Rezultati: U bolesnika koji boluju od SSc-a značajno je manje lučenje QS (1,93; p<0,001) i QSS (3,32; p<0,001) u odnosu na zdravu populaciju. Snižene su pH-vrijednosti sline (6,16; p=0,001). Sveukupni rezultati OHIP49 testa značajno su lošiji u odnosu na kontrolnu skupinu (43,68; p<0,001) što se odnosi i na sastavnice OHIP49 izuzimajući psihološku nelagodnost. Kvaliteta oralnog zdravlja korelira s Medsger score (r=0,430; p=0,016) i s mRSS-om (r=0,521; p=0,003). Bolesnici sa SSc-om imaju više karioznih, izvađenih i plombiranih zubi (25,68; p=0,003) i manji međučeljusni razmak (3,79; p<0,001) u odnosu na kontrolne ispitanike. Viši rezultati OHIP49 potvrđeni su u bolesnika koji boluju od SSc-a s nižim SES-om (p=0,001).
Zaključak: Smanjeno sveukupno lučenje sline uz niže pH-vrijednosti sline korelira s lošijim KEP-om, manjim brojem zubi i međučeljusnim rasponom, kao i lošijim oralnim zdravljem. Lošije oralno zdravlje korelira s promjenama kože i težom kliničkom slikom, kao i nižim stupnjem obrazovanja bolesnika koji boluju od SSc-a.Introduction: SSc is a rare autoimmune disease characterized by excessive tissue fibrosis. Due to fibrosis of the salivary glands and atrophy of the acinus, there is a reduced secretion of saliva. Decreased saliva pH values and changes in the oral microbial flora increase the risk of developing dental caries, which is reflected in overall oral health.
Objective: To explore the relationship of overall, unstimulated and stimulated saliva and saliva pH on the oral health quality in SSc patients without associated SS or SS-related autoantibodies. To examine whether there is a correlation between oral health quality and clinical picture severity in SSc patients.
Methods: The study involved 31 patients with SSc, of which 90% had a diffuse form, and 31 control subjects without SSc. This cross-sectional study was conducted from August 2015 to February 2017. All subjects met the American College of Rheumatology criteria for a definitive diagnosis. The state of oral health was determined by a dental examination of the oral cavity. We examined QS, QSS, pH, KEP, Periodontal Status, and Intermaxillary Range. We examined the quality of life using the OHIP49 questionnaire. The severity of the clinical picture and the activity of the underlying condition with the use of clinical and laboratory parameters were determined on the premises of the modified Medsger score and skin involvement by the modified Rodnan skin score. The level of education was used as a surrogate for SES measures, measuring “not completed secondary school” and “completed secondary school or higher”. Data was processed for data distribution normality by the Shapiro-Wilk distribution normality test. The groups were compared using the Student’s t-test or the Mann-Whitney test. Differences between the control group and SSc patients were tested by one-way analysis of variance, ie by the Kruscal Walis test for non-parametric data. Correlations between variables were tested using the Pearson test, or Spearman's test for nonparametric variables. The degree of significance p <0.05 was considered significant.
Results: In SSc patients there was significantly less secretion of QS (1.93; p <0.001) and QSS (3.32; p <0.001) compared to the healthy population. Saliva pH values were lowered (6.16; p = 0.001). Overall OHIP49 was significantly worse compared to the control group (43.68; p <0.001), which also applies to the components excluding psychological discomfort. Oral health quality correlated with Medsger score (r = 0.430; p = 0.016) and mRSS (r = 0.521; p = 0.003).
Patients with SSc have more carious, extracted and filled teeth (25.68; p = 0.003) and a smaller intermaxillary range (3.79; p <0.001) compared to control subjects. Higher OHIP49 results were confirmed in SSc patients with lower SES (p = 0,001).
Conclusion: Decreased overall salivation at lower pH values correlates with poorer KEP, fewer teeth and intermaxillary range as well as poorer oral health. Poorer oral health correlates with skin changes and a more severe clinical picture, as well as a lower level of education of SSc patients
Quality of oral health in patients with systemic sclerosis
No full textUvod: SSc je rijetka autoimuna bolest obilježena ekcesivnom fibrozom tkiva. Zbog fibroze žlijezda slinovnica i atrofije acinusa dolazi do smanjenog lučenja sline. Snižene pH-vrijednosti sline i promjene oralne mikrobijalne flore povećavaju rizik razvoja zubnog karijesa što se odražava na sveukupno oralno zdravlje.
Cilj: Istražiti odnos sveukupne, nestimulirane i stimulirane sline i pH-vrijednosti sline i kvalitete oralnog zdravlja u bolesnika koji boluju od SSc-a bez pridruženog SS-a ili autoprotutijela vezanih za SS. Ispitati postoji li korelacija između kvaliteta oralnog zdravlja, težine bolesti i kožne zahvaćenosti u ovih bolesnika.
Metode: U istraživanju je sudjelovao 31 bolesnik sa SSc-om, od kojih je 90% imalo difuzni oblik, te 31 kontrolni ispitanik bez SSc-a. Ovo presječno istraživanje provodilo se od kolovoza 2015. do veljače 2017. godine. Svi su ispitanici ispunjavali kriterije Američkog koledža za reumatologiju (American College of Rheumatology) za dijagnozu SSc-a. Stanje oralnog zdravlja određivano je stomatološkim pregledom usne šupljine. Istraživan je QS, QSS, pH-vrijednost sline, KEP, parodontalni status i međučeljusni razmak. Kvaliteta života ispitivana je pomoću upitnika OHIP49. Težina bolesti procijenjena je na osnovi tzv. modificiranog Medsger score, a zahvaćenost kože modificiranim Rodnanovim kožnim testom. Stupanj obrazovanja koristio se kao zamjenska mjera SES-a. Podaci su obrađeni za normalnost distribucije podataka Shapiro-Wilkovim testom. Skupine su se uspoređivale pomoću Studentova t-testa ili Mann-Whitneyjeva testa. Razlike između kontrolne skupine i bolesnika koji su bolovali od SSc-a testirale su se jednosmjernom analizom varijance, odnosno Kruscal-Walisovim testom za neparametrijske podatke. Korelacije između varijabli testirale su se pomoću Pearsonova testa, odnosno Spearmanova testa za neparametrijske varijable, p<0,05 smatrao se statistički značajnim.
Rezultati: U bolesnika koji boluju od SSc-a značajno je manje lučenje QS (1,93; p<0,001) i QSS (3,32; p<0,001) u odnosu na zdravu populaciju. Snižene su pH-vrijednosti sline (6,16; p=0,001). Sveukupni rezultati OHIP49 testa značajno su lošiji u odnosu na kontrolnu skupinu (43,68; p<0,001) što se odnosi i na sastavnice OHIP49 izuzimajući psihološku nelagodnost. Kvaliteta oralnog zdravlja korelira s Medsger score (r=0,430; p=0,016) i s mRSS-om (r=0,521; p=0,003). Bolesnici sa SSc-om imaju više karioznih, izvađenih i plombiranih zubi (25,68; p=0,003) i manji međučeljusni razmak (3,79; p<0,001) u odnosu na kontrolne ispitanike. Viši rezultati OHIP49 potvrđeni su u bolesnika koji boluju od SSc-a s nižim SES-om (p=0,001).
Zaključak: Smanjeno sveukupno lučenje sline uz niže pH-vrijednosti sline korelira s lošijim KEP-om, manjim brojem zubi i međučeljusnim rasponom, kao i lošijim oralnim zdravljem. Lošije oralno zdravlje korelira s promjenama kože i težom kliničkom slikom, kao i nižim stupnjem obrazovanja bolesnika koji boluju od SSc-a.Introduction: SSc is a rare autoimmune disease characterized by excessive tissue fibrosis. Due to fibrosis of the salivary glands and atrophy of the acinus, there is a reduced secretion of saliva. Decreased saliva pH values and changes in the oral microbial flora increase the risk of developing dental caries, which is reflected in overall oral health.
Objective: To explore the relationship of overall, unstimulated and stimulated saliva and saliva pH on the oral health quality in SSc patients without associated SS or SS-related autoantibodies. To examine whether there is a correlation between oral health quality and clinical picture severity in SSc patients.
Methods: The study involved 31 patients with SSc, of which 90% had a diffuse form, and 31 control subjects without SSc. This cross-sectional study was conducted from August 2015 to February 2017. All subjects met the American College of Rheumatology criteria for a definitive diagnosis. The state of oral health was determined by a dental examination of the oral cavity. We examined QS, QSS, pH, KEP, Periodontal Status, and Intermaxillary Range. We examined the quality of life using the OHIP49 questionnaire. The severity of the clinical picture and the activity of the underlying condition with the use of clinical and laboratory parameters were determined on the premises of the modified Medsger score and skin involvement by the modified Rodnan skin score. The level of education was used as a surrogate for SES measures, measuring “not completed secondary school” and “completed secondary school or higher”. Data was processed for data distribution normality by the Shapiro-Wilk distribution normality test. The groups were compared using the Student’s t-test or the Mann-Whitney test. Differences between the control group and SSc patients were tested by one-way analysis of variance, ie by the Kruscal Walis test for non-parametric data. Correlations between variables were tested using the Pearson test, or Spearman's test for nonparametric variables. The degree of significance p <0.05 was considered significant.
Results: In SSc patients there was significantly less secretion of QS (1.93; p <0.001) and QSS (3.32; p <0.001) compared to the healthy population. Saliva pH values were lowered (6.16; p = 0.001). Overall OHIP49 was significantly worse compared to the control group (43.68; p <0.001), which also applies to the components excluding psychological discomfort. Oral health quality correlated with Medsger score (r = 0.430; p = 0.016) and mRSS (r = 0.521; p = 0.003).
Patients with SSc have more carious, extracted and filled teeth (25.68; p = 0.003) and a smaller intermaxillary range (3.79; p <0.001) compared to control subjects. Higher OHIP49 results were confirmed in SSc patients with lower SES (p = 0,001).
Conclusion: Decreased overall salivation at lower pH values correlates with poorer KEP, fewer teeth and intermaxillary range as well as poorer oral health. Poorer oral health correlates with skin changes and a more severe clinical picture, as well as a lower level of education of SSc patients
Quality of oral health in patients with systemic sclerosis
No full textUvod: SSc je rijetka autoimuna bolest obilježena ekcesivnom fibrozom tkiva. Zbog fibroze žlijezda slinovnica i atrofije acinusa dolazi do smanjenog lučenja sline. Snižene pH-vrijednosti sline i promjene oralne mikrobijalne flore povećavaju rizik razvoja zubnog karijesa što se odražava na sveukupno oralno zdravlje.
Cilj: Istražiti odnos sveukupne, nestimulirane i stimulirane sline i pH-vrijednosti sline i kvalitete oralnog zdravlja u bolesnika koji boluju od SSc-a bez pridruženog SS-a ili autoprotutijela vezanih za SS. Ispitati postoji li korelacija između kvaliteta oralnog zdravlja, težine bolesti i kožne zahvaćenosti u ovih bolesnika.
Metode: U istraživanju je sudjelovao 31 bolesnik sa SSc-om, od kojih je 90% imalo difuzni oblik, te 31 kontrolni ispitanik bez SSc-a. Ovo presječno istraživanje provodilo se od kolovoza 2015. do veljače 2017. godine. Svi su ispitanici ispunjavali kriterije Američkog koledža za reumatologiju (American College of Rheumatology) za dijagnozu SSc-a. Stanje oralnog zdravlja određivano je stomatološkim pregledom usne šupljine. Istraživan je QS, QSS, pH-vrijednost sline, KEP, parodontalni status i međučeljusni razmak. Kvaliteta života ispitivana je pomoću upitnika OHIP49. Težina bolesti procijenjena je na osnovi tzv. modificiranog Medsger score, a zahvaćenost kože modificiranim Rodnanovim kožnim testom. Stupanj obrazovanja koristio se kao zamjenska mjera SES-a. Podaci su obrađeni za normalnost distribucije podataka Shapiro-Wilkovim testom. Skupine su se uspoređivale pomoću Studentova t-testa ili Mann-Whitneyjeva testa. Razlike između kontrolne skupine i bolesnika koji su bolovali od SSc-a testirale su se jednosmjernom analizom varijance, odnosno Kruscal-Walisovim testom za neparametrijske podatke. Korelacije između varijabli testirale su se pomoću Pearsonova testa, odnosno Spearmanova testa za neparametrijske varijable, p<0,05 smatrao se statistički značajnim.
Rezultati: U bolesnika koji boluju od SSc-a značajno je manje lučenje QS (1,93; p<0,001) i QSS (3,32; p<0,001) u odnosu na zdravu populaciju. Snižene su pH-vrijednosti sline (6,16; p=0,001). Sveukupni rezultati OHIP49 testa značajno su lošiji u odnosu na kontrolnu skupinu (43,68; p<0,001) što se odnosi i na sastavnice OHIP49 izuzimajući psihološku nelagodnost. Kvaliteta oralnog zdravlja korelira s Medsger score (r=0,430; p=0,016) i s mRSS-om (r=0,521; p=0,003). Bolesnici sa SSc-om imaju više karioznih, izvađenih i plombiranih zubi (25,68; p=0,003) i manji međučeljusni razmak (3,79; p<0,001) u odnosu na kontrolne ispitanike. Viši rezultati OHIP49 potvrđeni su u bolesnika koji boluju od SSc-a s nižim SES-om (p=0,001).
Zaključak: Smanjeno sveukupno lučenje sline uz niže pH-vrijednosti sline korelira s lošijim KEP-om, manjim brojem zubi i međučeljusnim rasponom, kao i lošijim oralnim zdravljem. Lošije oralno zdravlje korelira s promjenama kože i težom kliničkom slikom, kao i nižim stupnjem obrazovanja bolesnika koji boluju od SSc-a.Introduction: SSc is a rare autoimmune disease characterized by excessive tissue fibrosis. Due to fibrosis of the salivary glands and atrophy of the acinus, there is a reduced secretion of saliva. Decreased saliva pH values and changes in the oral microbial flora increase the risk of developing dental caries, which is reflected in overall oral health.
Objective: To explore the relationship of overall, unstimulated and stimulated saliva and saliva pH on the oral health quality in SSc patients without associated SS or SS-related autoantibodies. To examine whether there is a correlation between oral health quality and clinical picture severity in SSc patients.
Methods: The study involved 31 patients with SSc, of which 90% had a diffuse form, and 31 control subjects without SSc. This cross-sectional study was conducted from August 2015 to February 2017. All subjects met the American College of Rheumatology criteria for a definitive diagnosis. The state of oral health was determined by a dental examination of the oral cavity. We examined QS, QSS, pH, KEP, Periodontal Status, and Intermaxillary Range. We examined the quality of life using the OHIP49 questionnaire. The severity of the clinical picture and the activity of the underlying condition with the use of clinical and laboratory parameters were determined on the premises of the modified Medsger score and skin involvement by the modified Rodnan skin score. The level of education was used as a surrogate for SES measures, measuring “not completed secondary school” and “completed secondary school or higher”. Data was processed for data distribution normality by the Shapiro-Wilk distribution normality test. The groups were compared using the Student’s t-test or the Mann-Whitney test. Differences between the control group and SSc patients were tested by one-way analysis of variance, ie by the Kruscal Walis test for non-parametric data. Correlations between variables were tested using the Pearson test, or Spearman's test for nonparametric variables. The degree of significance p <0.05 was considered significant.
Results: In SSc patients there was significantly less secretion of QS (1.93; p <0.001) and QSS (3.32; p <0.001) compared to the healthy population. Saliva pH values were lowered (6.16; p = 0.001). Overall OHIP49 was significantly worse compared to the control group (43.68; p <0.001), which also applies to the components excluding psychological discomfort. Oral health quality correlated with Medsger score (r = 0.430; p = 0.016) and mRSS (r = 0.521; p = 0.003).
Patients with SSc have more carious, extracted and filled teeth (25.68; p = 0.003) and a smaller intermaxillary range (3.79; p <0.001) compared to control subjects. Higher OHIP49 results were confirmed in SSc patients with lower SES (p = 0,001).
Conclusion: Decreased overall salivation at lower pH values correlates with poorer KEP, fewer teeth and intermaxillary range as well as poorer oral health. Poorer oral health correlates with skin changes and a more severe clinical picture, as well as a lower level of education of SSc patients
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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