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Interval T Peak – T End pada Elektrokardiogram sebagai Penanda Keberhasilan Reperfusi Pasien Infark Miokard Akut Elevasi Segmen ST yang Menjalani Terapi Fibrinolitik di Rumah Sakit Haji Adam Malik Medan
No full textLatar Belakang : Target utama penatalaksanaan IMA-EST adalah terapi reperfusi
segera, dalam 12 jam pertama onset dapat dilakukan dengan IKP primer ataupun
fibrinolitik. Walaupun efektifitas IKP primer lebih unggul, terapi fibrinolitik
memiliki kelebihan dalam hal ketersediaan dan sumber daya sehingga risiko delay
menjadi lebih rendah. Penilaian keberhasilan fibrinolitik sangat penting untuk dasar
keputusan selanjutnya, resolusi segmen ST menggambarkan perfusi miokardial dan
punya makna klinis yang lebih baik. Interval T peak dan T end (Tpe) merefleksikan
transmural dispersion of repolarization (TDR) yang dapat menjadi alternatif dan
tambahan penilaian reperfusi. Penelitian ini bertujuan untuk mengetahui penurunan
interval Tpe dapat menjadi penanda keberhasilan reperfusi pasien IMA-EST yang
menjalani terapi fibrinolitik, sehingga diharapkan dapat menjadi alat bantu dan
bahan pertimbangan tambahan dalam tatalaksana kasus sehari-hari.
Metode : Penelitian potong lintang ini melibatkan 86 pasien IMA-EST onset ≤ 12
jam yang menjalani terapi fibrinolitik sejak periode oktober 2017 hingga juli 2021
di RSUP H. Adam Malik Medan. Interval Tpe dan cTpe [jarak RR(s)/√Tpe (ms)]
diukur sebelum dan 90 menit sesudah fibrinolitik kemudian perubahannya berupa
selisih (ms) dan resolusi (%) dihubungankan dengan indikator keberhasilan
reperfusi yang dinilai dengan resolusi segmen ST. Analisis statistik dilakukan
dengan menggunakan uji beda dua rerata dan receiver operating curve (ROC).
Hasil : Dari total 86 pasien, 53 pasien (61.2%) termasuk dalam kelompok
keberhasilan reperfusi. Penurunan nilai interval Tpe dan cTpe lebih besar dijumpai
pada kelompok keberhasilan reperfusi. Selisih Tpe dan cTpe memiliki sensitivitas
66% dan spesifisitas 75.8% dengan nilai area under curve (AUC) dan cut-off
masing-masing sebesar 72.6% dan 20 ms ; 71.5% dan 20.02 ms. Sedangkan
resolusi Tpe & cTpe masing-masing sebesar 72.6% dan 16.2% ; 73.7% dan 16.2%
dengan sensitivitas 66% dan spesifisitas 72.7%.
Kesimpulan : Penurunan interval Tpe dan cTpe dapat menjadi penanda
keberhasilan reperfusi pasien IMA-EST yang menjalani terapi fibrinolitik. Resolusi
cTpe memiliki nilai AUC yang paling baik dalam memprediksi keberhasilan
reperfusi.Background : The goal of STEMI treatment is immediate reperfusion therapy, in
the first 12 hours of onset it can be achieved either with primary PCI or fibrinolytic.
Although the superiority of effectiveness with primary PCI, fibrinolytic has
advantages in terms of availability and resources so that the risk of delay is lower.
Assesment of succesfull fibrinolytic is the key to base further decisions, ST segment
resolution reflects myocardial perfusion and has better clinical values. T peak and
T end (Tpe) interval reflects transmural dispersion of repolarization (TDR) which
can be an alternative and additional assessment of reperfusion. This study aims to
determine if Tpe interval can be a marker of successful reperfusion in patients with
STEMI undergoing fibrinolytic therapy.
Method : This is a crossectional study involving 86 patients with STEMI ≤ 12 hours
undergoing fibrinolytic treatment from october 2017 untill july 2021 in Adam
Malik Hospital Medan. Tpe and cTpe [RR (s)/√Tpe (ms)] interval were measured
before and after fibrinolytic treatment and then the changes in the form of difference
(ms) and resolution (%) were associated with indicator of successful reperfusion as
assessed by ST segment resolution. Statistical analysis was performed using t-test
and receiver operating curve (ROC).
Results : Among 86 patients, 53 patients (61.2%) were included in the successful
reperfusion group. The decrease in the value of Tpe and cTpe was greater in the
successful reperfusion group. The difference of Tpe and cTpe has a sensitivity of
66% dan specificity of 75.8% with area under curve (AUC) and cut-off values of
72.6% and 20 ms ; 71.5% and 20.02 ms, respectively. While the resolution of Tpe
and cTpe were 72.6% and 16.2% ; 73.7% and 16.2%, respectively with sensitivity
of 66% and specificity of 72.7%.
Conclusions : The Tpe and cTpe interval reduction can be a marker of successful
reperfusion in patients with STEMI treated with fibrinolytic therapy. The cTpe
resolution has the best AUC value in predicting successful reperfusion.120 HalamanTesis Magiste
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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