100,455 research outputs found
An empirical investigation of Advanced Manufacturing Technology investment patterns: evidence from a developing country
No full textAdvanced manufacturing technology (AMT) investment patterns in developing countries is in need of further investigation, particularly in the light of the conflicting evidence from the literature. This paper provides new evidence on AMT investment patterns from the Turkish automotive industry and develops a taxonomy by exploring the relationships between AMT investment patterns, ownership structure, firm size and performance. Analysis of industry survey data suggests the existence of three groups with different AMT investment strategies. Results suggest that AMT investment patterns are not only significantly correlated with firm performance or ownership, but also reveals significant differences in manufacturing performance across investment patterns. (C) 2013 Elsevier B.V. All rights reserved.Selcuk University Scientific Research Project Fund (BAP)Thanks are due to two reviewers for their valuable comments. In carrying out this research, the third author has been supported by the Selcuk University Scientific Research Project Fund (BAP)
Operational and environmental performance measures in a multi-product closed-loop supply chain
No full textThis paper investigates a number of operational and environmental performance measures, in particular those related to transportation operations, within a closed-loop supply chain. A mathematical model in the form of a linear programming formulation is used to model the problem, which captures the trade-offs between various costs, including those of emissions and of transporting commodities within the chain. Computational results are presented for a number of scenarios, using a realistic network instance.<br/
Modeling and optimizing the integrated problem of closed-loop supply chain network design and disassembly line balancing
No full textThis paper describes an integrated model that jointly optimizes the strategic and tactical decisions of a closed-loop supply chain (CLSC). The strategic level decisions relate to the amounts of goods flowing on the forward and reverse chains. The tactical level decisions concern balancing disassembly lines in the reverse chain. The objective is to minimize costs of transportation, purchasing, refurbishing, and operating the disassembly workstations. A nonlinear mixed integer programming formulation is described for the problem. Numerical examples are presented using the proposed model
Senkronize larinks ve nazal vestibul SCC: Olgu sunumu
No full textAydın S, Demir MG, Dikmen B, Paksoy M, Cakıl T, Coruk S. Senkronize larinks ve nazal vestibul SCC: Olgu sunumu 14. Rinoloji kongresi
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Assessment of Epstein-Barr virus, Candida albicans, and some periodontal pathogens in rheumatoid arthritis patients with periodontitis
No full textOBJECTIVE: To comparatively investigate the periodontal results and microbial load in subgingival biofilm samples (SBS) in rheumatoid arthritis subjects and healthy volunteers.METHODS: One hundred twenty subjects were classified into different cohorts: healthy (H-C); periodontitis with good systemic health (H-P); rheumatoid arthritis (RA) and good periodontal health (RA-C); and periodontitis with RA (RA-P). The periodontal parameters were recorded, and SBS were collected to determine periodontal pathogens including Epstein-Barr Virus (EBV) and Candida albicans using reverse transcription-polymerase chain reaction (RT-PCR). RESULTS: Subjects that had greater disease course, determined by moderate or high disease activity scores 28 (DAS28), suffered from worse oral health conditions (higher plaque index, gingival index, bleeding on probing, probing depth, and excessive clinical attachment loss) than those with low DAS28 scores. A higher prevalence of Treponema denticola (T. denticola) was observed in the RA-P group. Cyclic citrullinated peptide was associated with the occurrence of T. denticola and Campylo-bacter rectus. DAS28 using C-reactive protein (DAS28-CRP) had a significant association with Capnocytophaga gingivalis and EBV. The duration of the RA disease was associated with the presence of T. denticola.CONCLUSION: Subgingival microbial difference could reliably discriminate RA from healthy individuals. Especially, T. denti-cola and EBV may play a key role in periodontitis associated with RA
Fuzzy Decision-Making
No full textIn this chapter, the subject of the supplier selection problem using a fuzzy decision-making approach, judging by the impact of smart and sustainable operations, was studied. Nine smart and nine sustainable criteria were determined to evaluate five alternative suppliers and consider them as two distinct groups. The two-objective model developed for the solution of the problem tries to maximize the smartness and sustainability values of the supply separately while meeting the problem-specific constraints. The coefficients for the objective functions were obtained by evaluating the smart and sustainable maturity levels of the potential suppliers, and the aim was to purchase more from suitable suppliers according to the relative importance of the objectives. Then the developed multi-objective model was advanced fuzzy linear programming by benefitting from fuzzy decision-making to get the optimum solution to the problem. Afterward, different smart and sustainability weight pairs were determined considering the expectations of the decision-makers, and the results obtained from all scenarios were analyzed by applying the weighted additive method. © 2023 selection and editorial matter, Turan Paksoy and Muhammet Deveci; individual chapters, the contributors
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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