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Histopathological and immunohistochemical characterization of host-parasite interaction in visceral organs of mullets (Osteichthyes: Mugilidae) from Sardinian lagoons
Full text linkParasitic diseases in fish constitute a limiting factor for wild fishes and for aquaculture production. Extensive aquaculture in Sardinia is an important economical and traditional issue and mullets represent the most important product of this farming system.The aim of this study was to evaluate host-parasite interaction in visceral organs of Mugilidae species from Sardinian lagoons. A total of 239 mullets of different species were collected from four Sardinian lagoons. Lesions were examined macroscopically and histologically and also using histochemical and immunohistochemical techniques. Prevalence of Metazoan parasites (Digenean metacercariae, Myxobolus spp.andPolysporoplasma mugilis) were evaluated.MetacercariaeandMyxobolus sppinfections showed a similar prevalence in all lagoons, whereas a high prevalence of P.mugilis was observed in Cabras lagoon. Kidney was the most affected organ both for Metacercarie e Myxobolus species. Cellular immune response displayed a particularly relevant role with the development of chronic granulomatous reaction against parasites. Macrophages, epithelioid cells and fibroblasts were identified by immunohistochemestry as the main constitutive cell populations of granulomas but also eosinophilic granular cells and rodlet cells were associated to this response. Study of the granuloma structures revealed that Mugilidae displayed a common response against different metazoan parasites in visceral organs
Proteomic discovery and immunohistochemical validation of glucose metabolism-related enzymes as biomarkers in canine mammary tumours
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Co-occurrence of a metastatic mammary liposarcoma and an ovarian sex-cord stromal tumor in a dog
No full textSarcoma arising in the mammary gland is a rare tumor in dogs, and primary liposarcoma with metastatic behavior has never been previously reported among canine mammary tumors. A 14-year old female poodle had a mammary mass diagnosed as pleomorphic liposarcoma. Two years following surgical removal, the tumor recurred in the mammary gland with lymph node metastases. In addition, a sex-cord stromal tumor was identified in the ovary. Immunohistochemistry was performed on both tumors that were positive for oestrogen and progesterone receptors. Moreover, the ovarian tumor was positive for calretinin. This is the first report to the authors' knowledge, of the co-occurrence of a pleomorphic liposarcoma of the mammary gland and an ovarian sex-cord stromal (gonadostromal) tumor in the dog
Ovine Papillomaviruses: diversity, pathogenicity, and evolution
Full text linkThe family Papillomaviridae includes a plethora of viral species infecting virtually all vertebrates excluding amphibians, with astonishing impact on human and animal health. Although more than 250 species have been described in humans, the total number of papillomaviruses (PVs) discovered in animals does not reach up to this number. In animals, PV infections are mostly asymptomatic or can cause variable clinical conditions ranging from self-limiting papillomas and other cutaneous and mucosal benign lesions to cancer. Most of animal PV types have been discovered in cattle, dogs, horses, and cats with other farm host species remaining overlooked. In particular, the number of PV types so far identified in sheep is limited. This paper comprehensively reviews ovine PVs features, including viral taxonomy and evolution; genome organization; viral tropism and pathogenesis; macroscopical features and histopathological patterns, as well as available diagnostics tools. Data are critically presented and discussed in terms of impact on veterinary and public health. The development of future dedicated research is also discussed
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Histopathological and immunohistochemical characterization of host-parasite interaction in visceral organs of mullets (<i>Osteichthyes: Mugilidae</i>) from Sardinian lagoons
No full textParasitic diseases in fish constitute a limiting factor for wild fishes and for aquaculture production. Extensive aquaculture in Sardinia is an important economical and traditional issue and mullets represent the most important product of this farming system. The aim of this study was to evaluate host-parasite interaction in visceral organs of Mugilidae species from Sardinian lagoons. A total of 239 mullets of different species were collected from four Sardinian lagoons. Lesions were examined macroscopically and histologically and also using histochemical and immunohistochemical techniques. Prevalence of Metazoan parasites (Digenean metacercariae, Myxobolus spp. and Polysporoplasma mugilis) were evaluated. Metacercariae and Myxobolus spp infections showed a similar prevalence in all lagoons, whereas a high prevalence of P.mugilis was observed in Cabras lagoon. Kidney was the most affected organ both for Metacercarie e Myxobolus species. Cellular immune response displayed a particularly relevant role with the development of chronic granulomatous reaction against parasites. Macrophages, epithelioid cells and fibroblasts were identified by immunohistochemestry as the main constitutive cell populations of granulomas but also eosinophilic granular cells and rodlet cells were associated to this response. Study of the granuloma structures revealed that Mugilidae displayed a common response against different metazoan parasites in visceral organs
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