1,720,965 research outputs found
Gonadal function and response to growth hormone (GH) in boys with isolated GH deficiency and to GH and gonadotropins in boys with multiple pituitary hormone deficiencies
No full textObjective: To evaluate spermatogenesis in patients with isolated GH deficiency and multiple pituitary hormone deficiencies. Design: Treatment of isolated GH-deficient patients with recombinant human GH (weekly dose of 0.7 IU/kg) for 5.3 +- 0.4 (mean +- SD) years and cotreatment of multiple pituitary deficient patients with GH at the same dosage for 8.0 +- 0.4 years and hCG (2,000 IU, three times per week) and hMG (500 IU, two times per week) for 13.7 +- 1.1 months. Setting: Endocrine Pediatric Unit. Patients: Eight patients affected by isolated GH deficiency and seven by multiple pituitary hormone deficiencies. Main Outcome Measures: Serum LH, FSH, and T, testicular volume, semen volume, density, count, and motility. Results: Patients with isolated GH deficiency completed their pubertal development in 19.0 +- 3.5 months and patients with multiple pituitary hormone deficiencies in 13.7 +- 1.1 months. At the end of puberty, the two groups of patients had similar testicular volume, penis size, sperm concentration, motility, and morphology, although T levels and seminal volume were lower in isolated GH-deficient patients than in multiple pituitary deficient patients. Conclusions: The two groups of patients, treated specifically for their identified hormonal deficiencies, in the end had similar satisfactory reproductive results
Sviluppo puberale e fertilità nei soggetti con deficit combinato di ormone della crescita e gonadotropine
No full textSono stati studiati pazienti con deficit isolato di ormone della crescita e deficit combinato di ormone della crescita e gonadotropine. I risultati dopo trattamento dei deficit combinati con un protocollo utilizzante LH ed FSH ricombinanti hanno portato a risultati sovrapponibili in termini di sperimogramma tra i due gruppi, con buone probabilità per una futura fertilità
JOURNEY INTO THE REALM OF REQUESTS FOR HELP PRESENTED TO SEXUAL MEDICINE SPECIALISTS: INTRODUCING MALE SEXUAL DISTRESS
No full textIntroduction. The recent availability of noninvasive pharmacological remedies for male sexual function triggered an
exponential increase in the number of men requesting help in the sexuality area.
Aim. The Italian Society of Andrology explored requests for help, not included in formerly established clinical
categories of sexual medicine.
Methods. A central board of 67 andrologists identified new areas of requests for help, instrumental for a web-based
questionnaire, forwarded to 912 members of the Italian Society of Andrology. Results were submitted to an
independent consensus development panel.
Main Outcome Measures. A questionnaire response rate of 30.8% was considered acceptable according to standard
response rates of medical specialist samples.
Results. The Central Board interaction identified two new domains of requests for help: sexual distress and
unconventional requests for pro-erectile medications.Web-based questionnaire results suggested that such domains
account for 29% and 9% respectively of all requests for help already presented by male patients at sexual medicine
clinics. The Independent Consensus Development Panel issued a final consensus document; herewith, the statement
defining male sexual distress: A non-transitory condition and/or feeling of inadequacy such as to impair “sexual health”
(WHO working definition). Inadequacy can originate both from physiological modifications of male sexual functions, and from
diseases, dysfunctions, dysfunctional symptoms and dysmorphisms, both of andrological and non-andrological origin, which do not
relate to “erectile dysfunction” (NIH Consensus Development Panel definition), but that might also induce erectile dysfunction.
Sexual Distress can lead to a request for help which needs to be acknowledged.
Conclusion. The Italian Society of Andrology identified two new areas of requests for help concerning male sexual
issues: sexual distress and unconventional requests for pro-erectile medications. These domains, which do not
represent new diseases, nonetheless induce the sufferers to seek help and, accordingly, need to be acknowledged
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Effetti dell`impiego dei fluoruri nelle sindromi osteoporotiche: studio del contenuto minerale osseo mediante densitometria a scansione
No full textThe effects of bisphosphonate on patients with primary hyperparathyroidism
No full textIn this study authors determine the effects of bisphosphonate on patients with primary hyperparathyroidis
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