56 research outputs found
LUCIAN BLAGA DANS L’ESPACE EUROPÉEN: POUR UNE POÉSIE PHILOSOPHIQUE ? LE DANGER DES LECTURES DÉFORMANTES
No full textOur study is an analysis of Lucian Blaga’s poetry in the European culture, especially in the French and francophone milieu, through the existing translations. Blaga is an important figure of the 20th century: as he was, at the same time, a poet, philosopher, essayist, dramatic author, and novelist, his work is difficult to classify and runs the risk of distorting interpretations. The key-question of our debate will have in view the literary genre to which Blaga’s poetry may belong: can we really talk about “philosophical poetry”, as it was written at the same time as the construction of Blaga’s philosophical system? We consider that Blaga’s poetry and philosophy are analogous, but not to be confused; in this context, we prefer the syntagm “conceptual poetry” and will justify our choice by the fact that this poetry is built on theories concerning knowledge, the original phenomenon and the discovery of the cosmic mystery
Impactul internaționalizării asupra strategilor de marketing a instituției de învățământ superior
No full textȘIȘCAN, Ecaterina. Impactul internaționalizării asupra strategilor de marketing a instituției de învățământ superior. In: Performanţe într-o economie competitive: conf. şt. intern., Ediția a 6-a, 23-24 aprilie 2019. Chişinău: S. n., 2019, pp. 132-135. ISBN 978-9975-3308-9-3.Internationalization has become not only one of the most current issues of higher education, but also a viable development strategy for indigenous universities under the current global environment. The opening of national economies and the need to increase the export of educational services justify the increased interest of university management in internationalization in the context of globalization of the world economy. Within the limits of the present study, the author aims to study the theoretical aspects regarding the internationalization of higher education, the factors that influence the process of internationalization, as well as the implications of internationalization on the marketing decisions of the higher education institution. JEL: M31, I23
Development of the methodology for analyzing the turnover of receivables and payables
No full textAFANASIEVA, Ecaterina. Совершенствование методики анализа оборачиваемости дебиторской и кредиторской задолженностей = Development of the methodology for analyzing the turnover of receivables and payables. In: International scientific conference on accounting, ISCA 2022 [online]: Collection of scientific articles = Culegere de articole științifice, 11 Edition, April 1-2, 2022. Chişinău: ASEM, 2022, pp. 213-219. ISBN 978-9975-155-92-2 (PDF).The article is dedicated to the study of existing methods for the analysis of receivables and payables. The author identifies methodological contradictions in the existing approaches to turnover and their lack of information for the purpose of making managerial decisions. The author's methodology for calculating the turnover indicators of accounts receivable and accounts payable, depending on their role in the circulation of funds, is proposed. The calculation of indicators according to the current and proposed methodology is presented, a comparative analysis of the results is carried out, conclusions are drawn. CZU: 657.411.8; JEL: O12; DOI: 10.5281/zenodo.706384
Interventional treatment in elderly patients with severe aortic valve stenosis and coronary artery disease
No full textUniversitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroduction. Aortic stenosis (AS) is a valvular heart disease commonly found in the elderly patients and frequently is associated with coronary artery disease (CAD), sharing multiple risk factors and common pathophysiological mechanisms, such as age, smoking, hypertension, and hyperlipidemia. The prevalence of CAD in patients with severe AS is between 15% and 80% and the impact of coronary involvement on postprocedural outcomes is controversial and incompletely studied. Aim of study. This study aims to compare clinical and hemodynamic outcomes, as well as the rate of major adverse cardiovascular and cerebrovascular events (MACCE) in patients undergoing TAVI with PCI (patients with AS and CAD) versus isolated TAVI (patients with AS). Methods and materials. A retrospective study was performed that included 41 patients older than 70 years with a diagnosis of severe aortic valve stenosis and CAD. Patients were divided into two groups: 32 patients without significant coronary lesions and 9 patients with significant multivessel lesions and Syntax Score <22. In these patients, we aimed to assess the valvular pressure gradient, and aortic valve peak velocity, pre-procedural, post-procedural, 30 days and 1 year post-TAVI. To assess the postprocedural results, the rate of major adverse cardiovascular events (MACCE) is recorded, represented by: cardiovascular mortality, cerebrovascular accident, acute myocardial infarction or myocardial revascularization, readmission due to heart failure. Results. After analyzing the data, it was determined that in group I the proportion of men was 21.87%, compared to 22.2% in group no. II, and the average age was 78.15 ± 4.61 vs 75.66 ± 5.02, p<0,09. The mean values of the maximum transaortic pressure gradient were 93.11 mmHg ± 21.55 in group 1 and 103.07 mmHg ± 20.19, respectively, p<0,156; the mean transaortic pressure gradient 57.52 mmHg ± 15.25 vs 63.98 ± 15.0, p<0,156, and the mean value of the peak velocity through the aortic valve was 4.78 m/s ± 0.56 in group I and 5.05 m/s ± 0.54 in the second group, p<0,142. After the procedure, the average pressure gradient decreased impressively, the average value being 12.59 ± 5.62 mmHg vs 14.78 ± 8.73 mmHg, p< 0.338. The peak velocity of the jet through the aortic valve is 2.36 ± 0.50 m/s vs 2.53 ± 0.83 m/s, p< 0.361. In this study, one case of death associated with the procedure, which represents 3.12%, and 2 cases of stroke, which constituted 6.25%, were documented in group I. At the same time, in both groups 2 cases of readmission due to heart failure were reported. Conclusion. In patients with severe AS and complex CAD, TAVI + PCI was not associated with a higher rate of MACCE after a 12-month follow-up compared with patients with severe AS without CAD and approached by TAVI, probably due to the small study group and short follow-up period. Performing PCI before TAVI in patients with a Syntax score <22 appears to be safe, with no differences in echocardiographic parameters or MACCE compared to the group of patients without coronary lesions. Keywords. Aortic stenosis, transcatheter aortic valve implantation, coronary artery disease. and frequently is associated with coronary artery disease (CAD ), sharing multiple risk factors and common pathophysiological mechanisms, such as age, smoking, hyperten sion, and hyperlipidemia. The prevalence of CAD in patients with severe AS is between 15% and 80% and the impact of coronary involvement on postprocedural outcomes is controversial and incomple tely studied. Aim of study. This study aims to compare clinical and hemodynamic outcomes, as w ell as the rate of major adverse cardiovascular and cerebrovascular events (MACCE) in patients undergoing TAVI with PCI (patients with AS and CAD) versus isolated TAVI (patients with AS). Methods and materials. A retrospective study was performed that included 41 patients older than 70 years with a diagnosis of severe aortic valve stenosis and CAD. Patients were divided into two groups: 32 patients without significant coronary lesions and 9 patients with si gnificant multivessel lesions and Syntax Score <22. In these patients, we aimed to assess the valvular pressure gradient, and aortic valve peak velocity, pre-procedural, post-procedural, 30 days and 1 year post-T AVI. To assess the postprocedural results, the rate of major adverse cardiovascular events (MACCE) is recorded, represented by: cardiovascular mortality, cerebrovascular accident, acute myocardial infarction or myocardial revascularization, readmission due to heart failure. Results. After analyzing the data, it was determined that in group I the pr oportion of men was 21.87%, compared to 22.2% in group no. II, and the average age was 78.15 ± 4.61 vs 75.66 ± 5.02, p<0,09. The mean values of the maximum transaortic pressure gradient were 93.11 mmHg ± 21.55 in group 1 and 103.07 mmHg ± 20.19, respectively, p<0,156; the mean transaortic pressure gradient 57.52 mmHg ± 15.25 vs 63.98 ± 15.0, p<0,156, and the mean value of the peak velocity through the aortic valve was 4.78 m/s ± 0.56 in group I and 5.05 m/s ± 0.54 in the second group, p<0,142. After the procedure, the average pressure gradient decreased impressively, the average val ue being 12.59 ± 5.62 mmHg vs 14.78 ± 8.73 mmHg, p< 0.338. The peak velocity of the jet through the aortic valve is 2.36 ± 0.50 m/s vs 2.53 ± 0.83 m/s, p< 0.361. In this study, one case of death associate d with the procedure, which represents 3.12%, and 2 cases of stroke, which constituted 6.25%, were documente d in group I. At the same time, in both groups 2 cases of readmission due to heart failure were rep orted. Conclusion. In patients with severe AS and complex CAD, TAVI + PCI was not associated with a higher rate of MACCE after a 12-month follow-up compared with patie nts with severe AS without CAD and approached by TAVI, probably due to the small study gro up and short follow-up period. Performing PCI before TAVI in patients with a Syntax score <22 appea rs to be safe, with no differences in echocardiographic parameters or MACCE compared to the group of patient s without coronary lesions
Rolul politicii statale şi a iniţiativelor sectorului privat în formarea clusterelor economice: experienţa internaţională şi cazul Republicii Moldova
No full textRUSU, Ecaterina. Rolul politicii statale şi a iniţiativelor sectorului privat în formarea clusterelor economice: experienţa internaţională şi cazul Republicii Moldova. In: Competitivitate şi inovare în economia cunoaşterii [online]: conf. şt. intern., ed. a 21-a: Lucrări ştiinţifice., 27-28 sept., 2019. – Chişinău: ASEM, 2019, pp. 405-413. ISBN 978-9975-75-968-7.Economic clusters proved their important role in helping societies to overcome the socioeconomic challenges of globalization, by making companies more competitive. Therefore, becoming an ingredient of territorial competitiveness, initiatives on cluster creation are carried out more and more frequently at the national, regional, and local level. Some initiatives are generated by the state, aiming to reach certain national strategic objectives, others have their roots in the private sector, the decision of companies to join their efforts for improving value chain. The author attempts to analyze the role of private sector initiatives and of the state programs / policies in the development of clusters, also by comparing the relevant experience both at the EU level, and at the level of countries, particularly focusing on the cases of France, Germany, Romania and R. Moldova. The research methods primarily consisted in analysis and synthesis of information, of various policy papers, guide-books and reports on clusters implementation. As a conclusion the author underlines that both public and private sectors have an important role in the clusterization process. In some countries clusters emerged as a natural tendency of companies, in others the state institutions played a central role. Additionally, in the developed countries, the role of state evolved from simple stimulation of cluster formation to their support in becoming global and innovative hubs. By contrast, in the developing countries the clusters phenomena are not widely spread, hence the state has to focus on policies and programs of clusters promotion and development. JEL: O2, O5
Postoperative evolution and incidence of complications after transcatheter aortic valve implantation in the period 2019-2025
No full textUniversitatea de Stat de Medicină și Farmacie „Nicolae Testemițanu”, Chișinău, Republica MoldovaIntroducere. Începând cu anul 2019, în Republica Moldova implantarea transcateter de valvă aortică (TAVI) a devenit o alternativă eficientă pentru tratamentul stenozei aortice (SA) la pacienţii vârstnici, însă în pofida succesului acestei proceduri, complicaţiile peri- şi postprocedurale rămân inevitabile. Scop. Analiza evoluţiei clinice şi a complicaţiilor postoperatorii la pacienţii supuşi TAVI, atât în perioada periprocedurală, cât şi la intervale de 30 de zile, şase luni şi un an postintervenţie. Material şi metode. În studiu au fost incluşi 171 de pacienţi supuşi TAVI în perioada anilor 2019-2025, fiind monitorizată evoluţia lor clinică pe termen scurt şi mediu. Vârsta medie a fost de 76,28 ± 4,842 ani, cu predominanţa femeilor (61,99%). S-au analizat evenimentele adverse cardiovasculare majore (MACE) şi complicaţiile periprocedurale. Rezultate. Periprocedural, 29 pacienţi (16,96%) au prezentat complicaţii, precum: BAV grad III cu implantare de pacemaker (6,43%), complicaţii vasculare (4,68%), embolizare valvulară (1,17%), aritmii ventriculare (1,75%) şi deces procedural (1,17%). La 30 de zile, 10 pacienţi (5,84%) au prezentat reinternare cu insuficienţă cardiacă (IC) (4,09%), tromboză valvulară (0,58%) şi IMA (0,58%). La 6 luni, 6 pacienţi (4,44%) au avut tromboză valvulară (1,48%), reinternare cu IC (1,48%), BAV grad III (0,74%) şi deces non-cardiac (0,74%). La 1 an, 4 pacienţi (3,28%) au prezentat reinternare cu IC, BAV grad III, AVC şi deces non-cardiac (0,82% fiecare). Concluzii. Evaluarea complicaţiilor peri- şi postprocedurale la pacienţii vârstnici evidenţiază, în ultimii ani, o scădere semnificativă a acestora, datorită îmbunătăţirii continue a designului valvei, selecţiei riguroase a pacienţilor şi creşterii experienţei centrului şi operatorilor.Introduction. Starting in 2019, in the Republic of Moldova, transcatheter aortic valve implantation (TAVI) has become an effective alternative for the treatment of aortic stenosis (AS) in elderly patients. However, despite the success of this procedure, peri- and postprocedural complications remain inevitable. Objective. Clinical evolution and postoperative complications in patients undergoing TAVI, assessed during the periprocedural period and at follow-ups of 30 days, 6 months, and 1-year post-procedure. Material and methods. The study included 171 patients who underwent TAVI between 2019 and 2025, with their clinical course monitored over the short and medium term. The mean age was 76.28 ± 4.842 years, with a predominance of female patients (61.99%). Major adverse cardiovascular events (MACE) and periprocedural complications were analyzed. Results. Periprocedurally, 29 patients (16.96%) experienced complications, including third-degree AV block with pacemaker implantation (6.43%), vascular complications (4.68%), valve embolization (1.17%), ventricular arrhythmias (1.75%) and procedure-related death (1.17%). At 30 days, 10 patients (5.84%) had HF readmission (4.09%), valve thrombosis (0.58%) and MI (0.58%). At 6 months, 6 patients (4.44%) showed valve thrombosis (1.48%), HF readmission (1.48%), third-degree AV block (0.74%) and non-cardiac death (0.74%). At 1 year, 4 patients (3.28%) experienced HF readmission, AV block, stroke, and non-cardiac death (0.82% each). Conclusion. The evaluation of peri- and postprocedural complications in elderly patients has shown a significant decrease in recent years, due to the continuous improvement of valve design, rigorous patient selection, and the growing experience of both the center and the operators
Explaining variations in international alignments: the post-Communist states and the choice between East and West, 1991 – 2014
No full textWhy did the post-Soviet states follow different foreign policy paths when compared to the rest of the former Communist states, after the dissolution of the USSR? Why states pursue inconsistent foreign policies and how do they choose alignment patterns? Why did some post-Communist governments in Europe take office promising one foreign policy orientation (either pro-West or pro-Russia) but later changed direction and adopted the opposite orientation? The research undertaken in this dissertation is based on extensive fieldwork activities in Eastern Europe: interviews with more than forty policymakers, including former Presidents, Prime Ministers, Ministers of Foreign Affairs, Ambassadors, diplomats and policy makers in both Ukraine and Moldova. In addition, the diplomatic archives of the Ministries of Foreign Affairs in Ukraine and Moldova, and the archives of the Moldovan Parliament were studied: more than 80,000 pages of diplomatic records, spanning from 1991 to 2006, were consulted. With insights from diplomatic archives and accounts from personal interviews with officials in charge of foreign policy making, the dissertation argues that political leaders in all post-Communist states chose alignment options based on a cost-benefit analysis, weighing whether the combination of incentives and constraints posed by orienting to the West or Russia did the most to further their overriding goal of acquiring or retaining power at home. In post-Communist countries where the EU and NATO offered a credible prospect for membership, political leaders from across the spectrum converged on a pro-Western foreign policy. In these cases, the promise of financial support and security guarantees from the West proved overwhelmingly attractive to domestic politicians, easily outweighing anything Russia might offer in hopes of reorienting the country’s foreign policy towards Moscow. By contrast, in the countries where the EU and NATO refused to grant a membership prospect, most notably to Ukraine and Moldova, the benefits of sticking to a pro-Western foreign policy were far less attractive and more uncertain, and less clearly superior to the incentives offered by Russia. In this context, vacillators and opportunists seeking national or personal gain from both the West and Russia – and potentially playing the two major poles off one another – came to the fore. Foreign policy alignments were therefore chosen strategically by national leaders depending on which they thought would best serve their interests. Both the pro-Western and the pro-Russia orientations were attractive alternatives: executive leaders picked one over another depending on their calculations as to whether Russia or the West would help them win and retain power at home. The EU’s refusal to offer binding commitments made its demands for political conditionality (such as pro-democracy and anti-corruption reforms) less effective and encouraged leaders in the region to vacillate in their foreign policy orientations. Meanwhile, with the West refusing to offer these states membership in its organizations, Russia exploited the internal weaknesses of these states to promote its foreign policy agenda and bolster its influence in the region.Ph.D.Includes bibliographical referencesby Ecaterina V. Locoma
Оптимальное время реперфузии у пациентов с острым инфарктом миокарда без подъёма сегмента СТ из группы сниженного ишемического риска
No full textThe aim of the study was to identify the optimal time window for performing effective percutaneous coronary reperfusion in patients with non-ST-segment elevation acute myocardial infarction (NSTEMI) who are part of the low ischemic risk group. 252 patients with NSTEMI and low ischemic risk who underwent coronary angioplasty up to 30 days after the onset of the infarction were evaluated the second day post-procedurally and at a distance of 6 months. The general group was randomized depending on the echocardiographic evolution. 131 patients with unfavorable evolution and 121 with more complete restoration of left ventricular contractile function. The time windows from the onset of myocardial infarction symptoms in which percutaneous myocardial reperfusion was applied were studied. Following the study, the time interval of 73 hours -14 days proved to be optimal in which a more favorable clinical and echocardiographic evolution is ensured.Scopul studiului a fost identificarea ferestrei optimale de timp pentru efectuarea reperfuziei coronariane percutanate eficiente la pacienți spitalizați cu infarct miocardic acut fără supradenivelare de segment ST (NSTEMI) care fac parte din grupul de risc ischemic scăzut. Au fost evaluați a doua zi postprocedural si la distanța de 6 luni 252 de pacienți cu NSTEMI și risc ischemic redus care au fost supuși angioplastiei coronariene pînă la 30 de zile de la debutul infarctului. Lotul general a fost randomizat în dependență de evoluție ecocardiografică. 131 de pacienți cu evoluția nefavorabilă și 121 cu restabilirea mai deplina a funcției contractile de ventricol stîng. Au fost studiate ferestrele de timp de la debutul simptomelor de infarct miocardic în care a fost aplicată reperfuzia miocardică percutană. În urma studiului intervalul de timp 73 de ore -14 zile s-a dovedit a fi optimal în care se asigură o evoluție clinică și ecocardiografică mai favorabilă.Целью исследования было определить оптимальное временное окно для выполнения эффективной чрескожной коронарной реперфузии у пациентов с острым инфарктом миокарда без подъема сегмента ST (NSTEMI), которые относятся к группе низкого ишемического риска. 252 пациента с инфарктом миокарда без подъема сегмента ST и низким ишемическим риском, перенесших коронарную ангиопластику в срок до 30 дней после начала инфаркта, были обследованы при помощи эхокардиографии на второй день и на 6-ой месяц после вмешательства. Общая группа была рандомизирована в зависимости от эхокардиографической динамики. 131 больной с неблагоприятным течением и 121 с более полным восстановлением сократительной функции левого желудочка. Изучены временные окна от дебюта симптомов инфаркта миокарда, в которых применялась чрескожная реперфузия миокарда. По итогам исследования оптимальным оказался временной интервал от 73 часов до 14 дней, при котором обеспечивается более благоприятная клиническая и эхокардиографическая динамика
METHODS OF TEACHING MYTHOLOGY IN HIGHER EDUCATION INSTITUTIONS WITH ARTISTIC PROFILE
No full textIn the present work there is an analysis of some aspects concerning the methods of teaching Mythology in a higher education institution with artistic profile. On the basis of the example of the course of Mythology the author analyzes the special process of reciprocal connection of forming semantic knowledge of typical human archetypes. The author emphasizes the creation of a continuous educational system: school – college – higher education institution that include instructive forms and teaching methods that contribute to the preliminary training of future students of an artistic higher education institution. The author speaks about the existent teaching system at the Academy of Music, Theatre and Fine Arts and the problems related to it
The Lost Bathhouse of Maastricht
No full textImagining the ruins of a Roman bathhouse on a forgotten river site in Maastricht, the project reflects on the idea of authenticity and manipulation of history in architecture. The building is imagined as a ruin and reflects on the role of ruins in architecture and how the roman ritual of bathing can be interpreted in contemporary times. The new bathhouse forges a dialogue between the new and the fake-old, and the baths and the Jeker river, through a system of layering that aims to mitigate the scale and solidity of the ruin with the tactile, intimate spaces for bathing. The festive is manifested in the programme of pleasure and in the reinterpretation and fantastical recreation of the ancient roman past of Maastricht.Architecture, Urbanism and Building Science
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