96,719 research outputs found

    Flow cytometry protocols

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    THE EUROPEAN WORKING GROUP ON CLINICAL CELL ANALYSIS WAS FOUNDED IN 1996 in order to establish collaboration between 16 european clinical flow cytometric facilities. The goal of EWGCCA is the evaluation , standardization and advancement of novel flow cytometry assays, used for clinical cell analysis, diagnostic procedures and monitoring of therapy

    The screening of affective perinatal disorders in fathers: preliminary validation data of the Perinatal Assessment of Paternal Affectivity (PAPA).

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    THE SCREENING OF AFFECTIVE PERINATAL DISORDERS IN FATHERS: PRELIMINARY VALIDATION DATA OF THE PERINATAL ASSESSMENT OF PATERNAL AFFECTIVITY (PAPA) Baldoni Franco (1), Matthey Stephen (2), Agostini Francesca (1), Caretti Vincenzo (3), Minghetti Mattia (1), Giannotti Michele (1), D’Autilia Benedetta (1), Spelzini Federico (4), & the PAPA Team (1) Department of Psychology, University of Bologna, Italy (2) University of Sydney - South West Sydney Local Health District, Sydney, Australia (3) LUMSA University, Roma, Italy (4) Obstetrics and Gynecology Operating Unit, Infermi Hospital Rimini, AUSL Romagna, Italy [email protected] The assessment of perinatal affective disorders in fathers is a still unresolved problem, and currently no screening tool is sufficiently credited. The most common early screening instruments, like the EPDS, even when validated for fathers, do not take into account that men are usually less prone to reveal any psychological difficulty and tend to repress discomfort assuming externalizing strategies like: alcohol abuse, smoking, drug addiction or other maladjusted behaviors. As a consequence of their indefinite clinical features, these problems are often under-assessed or undiagnosed. The Perinatal Assessment of Paternal Affectivity (PAPA) (Baldoni, Matthey, Agostini, Schimmenti, & Caretti, 2016) is a new questionnaire for the screening of high-risk fathers during the perinatal period. It is the first tool for evaluating affective problems in males, considering different dimensions highlighted by recent research. It is fast and easy to administer, ethnic and socio-cultural influences are also considered. The incoming preliminary data from the Italian multicentric validation study of the PAPA, involving many public services (AUSLs Romagna, Cagliari, 15 Alta Padovana, Torino, Foggia and Roma1), will be presented. 600 couples of fathers and mothers (1200 parents) were involved in the study. All participants, at the 7th-8th month prenatal and at 3rd month postnatal, completed the following questionnaires: PAPA, CES-D, SCL-90-R, ASA, PSS, DAS and EPDS. Preliminary findings showed significant association between PAPA total and single scale scores with many scores on CES-D, SCL-90-R, ASA, PSS and DAS (P< .05). These data confirm the PAPA as a useful screening tool for the assessment of perinatal affective disorders in fathers. Despite it doesn’t allow an accurate diagnosis, it provides a simple and practical guide to the detection of high-risk fathers. In these cases, a more thorough diagnostic assessment and a possible treatment are required

    F-MACHOP IN ADVANCED AGGRESSIVE LYMPHOMA

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    The results of our ten years experience indicate that F-MACHOP, conceptually designed to exploit cell kinetic and synergistic principles, is an effective regimen with acceptable toxicity in a large proportion of adults with advanced stages of diffuse large cell or small non-cleaved cell lymphoma. More than 60% of all treated patients all expected to achieve long-term EFS. Patients achieving CR within 3 courses have a very high chance of being cured of their disease and do not require, in our opinion, intensification with other regimens. On the other hand the identification of a group of patients with poorer outcome (i.e. those failing to achieve an early CR) enabled testing of the potential efficacy of superintensive salvage regimens. Together with other 6 Italian hematologic institutions, we have recently participated in a prospective comparative randomized trial in which F-MACHOP was compared to MACOP-B in adults with advanced stages of diffuse large cell or small non-cleaved cell lymphoma. The preliminary results of this trial appear to confirm that F-MACHOP is an effective and tolerable regimen in such patients and there is a suggestion that its efficacy is superior to that of MACOP-B. This trial was closed to accrual in September 1991 and we look forward to the first complete analysis in March 1992

    Perinatal Assessment of Paternal Affectivity (PAPA). First validation in Italian samples.

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    Perinatal Assessment of Paternal Affectivity (PAPA). First validation in Italian samples. Baldoni F.1, Matthey S.2, Agostini F.1, Schimmenti A.3, Caretti V.4 1Department of Psychology, University of Bologna, Italy 2University of Sydney, Australia 3 Kore University of Enna, Italy 4 LUMSA University, Rome, Italy Background: The assessment of affective disorders in fathers during the perinatal period represents a difficult challenge for clinicians. The Perinatal Assessment of Paternal Affectivity (PAPA) (Baldoni et al., 2016) is a new self-report questionnaire for the screening of affective symptoms in fathers during the perinatal period. It has been developed in recent research on perinatal affective disorders and assesses different dimensions of paternal affective problems: anxiety, depression, hostility, relational and couple difficulties, somatic complaints, dangerous behaviors and addictions (smoke, alcohol, drugs, gambling, internet, physical or sexual compulsive and at risk behavior). The PAPA has a simple structure and is very fast and simple to complete. It also considers some ethnic and socio-cultural influences. Aim: This study presents the incoming preliminary data of a multicentric validation study of the PAPA that involved many Italian public services (AUSL Romagna, Cagliari, 15 Alta Padovana, Torino, Foggia, Roma1). Methods: Different samples of fathers and mothers (500 couples, 1000 parents) were involved in the study. All participants, at the VII-VIII months prenatal and at 3 months postnatal, completed the following questionnaires: PAPA (prenatal and postnatal versions), CES-D, SCL-90-R, Analogical Symptom Assessment (ASA), Perceived Stress Scale (PSS), Dyadic Adjustment Scale (DAS), EPDS. Statistical analyses were performed using IBM SPSS Statistics (Version 23). Results: Preliminary findings concerning the prenatal period showed significant association between PAPA total scores (P = .05) and single scale scores with many scores on CES-D, SCL-90-R, ASA, PSS and DAS. Discussion: Preliminary data of this Italian validation study confirm the PAPA as a useful tool for the screening of paternal affective disorders in the perinatal period. However, the PAPA doesn’t permit an accurate diagnosis but provides a simple and practical guide for detecting fathers at high-risk of perinatal affective alteration. In these cases, a more in-depth diagnostic assessment and a possible treatment are required. Reference: Baldoni, F., Matthey, S, Agostini, F., Schimmenti, A., & Caretti, V. (2016). Perinatal Assessment of Paternal Affectivity (PAPA): preliminary report on a new screening tool, Infant Mental Health Journal, 37 (Suppl. 1), 132-133

    Innocentius III papa, Liber de missarum mysteriis.

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    INNOCENTIUS III, papa. De missarum mysteriisNumérisation effectuée à partir d'un document original.Le prologue manque. (P. L., CCXVII, 775-916). F. Iv Fragment d'une lettre du légat Gérard Bianchi, cardinal de Sabine, au gardien des Frères Mineurs de Salerne, concernant l'absolution de Paul de Salerne, qui avait fait du commerce avec les Infidèles (1283)

    Outcome of 50 consecutive sinus lift operations.

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    Outcome of 50 consecutive sinus lift operations. Papa F, Cortese A, Maltarello MC, Sagliocco R, Felice P, Claudio PP. Source Department of Odontostomatologic and Maxillo Facial Sciences, University of Naples "Federico II", Italy. Abstract We report 50 patients who had sinus lift operations between 1995 and 1999 using different grafting materials [autologous bone, heterologous bone, and hydroxyapatite]. The casenote were analysed clinically (intraoperative and postoperative results and complications), radiographically (amount of augmented bone 6 months postoperatively), and histologically (quality of the new bone 12 months postoperatively). Our aim was to find out if the various bone grafting materials used resulted in different outcomes after adjustment for significant predictors. We found that hydroxyapatite was associated with the lowest rate of loss of grafted material (median, 2.4 mm) followed by the autologous bone from iliac crest (2.8 mm). Bovine bone shown the highest loss (3.3 mm). PMID: 15993284 [PubMed - indexed for MEDLIN
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