1,721,120 research outputs found
Thymopentin treatment in patients undergoing surgery for lung carcinoma: Analysis of actuarial survival
No full textThymopentin is increasingly used in cancer patients because it has been observed to be useful in preventing infections in the post-operatory period and follow radio and chemotherapy. Two hundred forty seven patients undergoing macroscopically radical exeresis for non-small-cell lung cancer were randomly assigned to thymopentin treatment or control group. The patients were staged according to TNM system indications and classified as follows; I = 138pts, II = 54pts, IIIa = 55pts. Drug regimen was 1 mg/kg/die in the 3/7 days before surgery and throughout the post-operatory period, and 1 mg/kg every other day in the first year. In subseqent years the frug was administered at the same dosage for one month every three. We calculated the profile of the lymphocyte Leu 1, 4, 7, 3a, 2a subpopulation, and the helper/suppressor ratio within the controll group both prior and following one year from the treatment. We also observed a significant increase of Leu 1, 4 and 3a profile. Survival curves obtained by actuarial evaluation of the patients treated with thymopentin vs non treated patients showed that after 66 months the probability of survival in stage I patients was 78% vs 60% (p < 0.05); in stage II, 65% VS 58% (p = n.s.); in stage IIIa, 16% vs 13% (p = n.s.). In our opinion a positive interaction on survival was probably obtained by an aspecific activation of the immune system; in stage I when exeresis reduces residual disease to a minimum; in stage II and IIIa aspecific stimulation, if any, did not result in increased survival
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Irreparable rotator cuff tears: challenges and solutions
Full text linkMichele Novi,1 Avinash Kumar,2 Paolo Paladini,3 Giuseppe Porcellini,4 Giovanni Merolla3,5 1Orthopaedic and Trauma Unit, University Hospital of Pisa, Pisa, Italy; 2Department of Orthopaedics, All India Institute of Medical Sciences, Patna, India; 3Shoulder and Elbow Unit, “D. Cervesi” Hospital, AUSL della Romagna, Ambito Territoriale di Rimini, Rimini, Italy; 4Orthopaedic and Trauma Unit, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy; 5“Marco Simoncelli” Biomechanics Laboratory, “D. Cervesi” Hospital, AUSL della Romagna, Ambito Territoriale di Rimini, Rimini, Italy Abstract: Irreparable rotator cuff tears are common conditions seen by shoulder surgeons, characterized by a torn and retracted tendon associated with muscle atrophy and impaired mobility. Direct fixation of the torn tendon is not possible due to the retracted tendon and lack of healing potential which result in poor outcome. Several treatment options are viable but correct indication is mandatory for a good result, pain improvement, and restoration of shoulder function. Patient can be treated either with a conservative program or surgically when necessary, by different available modalities like arthroscopic debridement, partial reconstruction, subacromial spacer, tendon transfer, and shoulder replacement with reverse prosthesis. The aim of this study was to review literature to give an overview of the available possible solutions, with indications and expected outcomes. Keywords: irreparable rotator cuff tear, arthroscopy, partial repair, tendon transfer, graft augmentatio
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Evaluation of the results of Shoulder Arthroplasty
No full textReview of methods for the evaluation of shoulder arthroplasty that in our experience have been most recently used at an international level, explaining characteristics and patterns of use, noting when there is a validated Italian version ready to use, with appropriate references
Different Approaches, Similar Outcomes: Same-Sex Marriage in Canada and South Africa
No full textIl saggio analizza con metodo comparativo il ruolo delle corti nazionali nel processo che ha portato al riconoscimento del matrimoniio tra persone dello stesso sesso negli ordinamenti canadese e sudafricano e si sofferma sull'influenza che il primo ha esercitato nei confronti del secondo
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
From Gay Rights to Same-Sex Marriage: A Brief History Through the Jurisprudence of US Federal Courts
No full textThe inverse prosthesis as a revision prosthesis in failures of shoulder hemiarthroplasty
No full textThe authors describe their series of seven cases of complications and failures of shoulder hemiarthroplasty that were submitted to revision surgery involving an inverse prosthesis. This prosthesis has for some time now been indicated in elderly patients with arthropathy caused by rupture of the cuff. In our cases this prosthesis was implanted in patients who had undergone shoulder hemiarthroplasty for fracture and for arthrosis. The Constant score was used for pre- and postoperative evaluation. Results at mid-term, from 2 to 4 years, indicate evident improvement in Constant score that rose from a mean of 23.14 preoperatively to a mean of 49.14 postoperatively. Despite the limited follow-up the authors suggest the use of the inverse prosthesis as an effective alternative solution in shoulder arthroplasty revision surgery
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