73 research outputs found

    Numerical modelling on super-diffusion of carbon-dioxide in coal

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    Case II (super)-diffusion is characterized by a diffusion like process that goes faster than the square root of time. Superdiffusion can occur in polymeric structures if a stress gradient enhances the diffusion process. In such a case the part of the polymer invaded by the penetrant, e.g. CO2, undergoes a transition in structure from the glass state to a rubber like state. In ideal cases the transition zone can propagate proportional to time. The Thomas & Windle model, a model that describes anomalous diffusion behavior in polymers, was also proposed to describe diffusion of CO2 in coal. The proposal was due to the similarities in structure between coal and glassy polymers. Coal has a molecular structure of carbon-carbon bonds with ‘open holes’ between the chains. If these holes are smaller in volume than the volume of a CO2-molecule, the uptake of CO2 leads to a geometric problem. The CO2 molecules will squeeze themselves into the structure, resulting into a swollen rubbery coal. This phenomenon is happening due to the fact that a carbon-carbon dioxide bond is thermodynamically favored above the carbon-carbon bond and is more stable than the other. Analysis of the Thomas & Windle model shows there is a time where diffusion is much faster than conventional diffusion. The results also show that super-diffusion is only a transitional effect, i.e., there is an initial phase where relaxation dominates, a transitional phase that exhibits anomalous diffusion and a long time phase that shows the typical square root of time behavior of an ordinary diffusion process. This study gives details of a numerical model used to solve the stress induced diffusion equation using the Finite Element Method implemented in Matlab. The numerical results show that for some favorable set of parameters diffusion can indeed be faster than Fickean diffusion during an intermediate stage. For other parameters the diffusion can be slower. A comparison to a laboratory result shows an example where diffusion appears to be slower.Petroleum EngineeringCivil Engineering and Geoscience

    Nabokov, “the Wretched Aksakov”, and Early English Translations of Sergei Aksakov’s Autobiographical Prose. Problems of Natural History

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    This article considers English translations of Sergei Aksakov‟s pastoral trilogy (1856-58), or parts of it, by „a Russian lady‟ (1871), James Duff (1916-24), and M. C. Beverley (1924), in the light of Vladimir Nabokov‟s pronouncements about literary translation in general and his dismissive statements about Aksakov as a writer. Particular attention is devoted to Aksakov‟s descriptions of the flora and wild life of the province of Ufa and the difficulties this posed for the translators. It concludes with selected passages from the trilogy in which these matters are especially prominent, in the author‟s English translation

    Phenolic Composition, Antibacterial And Antioxidant Activities Of Brazilian Red Propolis [composição Fenólica, Atividade Antibacteriana E Antioxidante Da Própolis Vermelha Brasileira]

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    Propolis is a resinous hive product collected by honeybees from various plant sources. It has a complex chemical composition, constituted by various phenolic compounds. Extracts of increasing polarity (n-hexane, chloroform, and ethanol) were obtained from a sample of red propolis from the state of Alagoas. Assays were carried out for determination of contents of phenolics, along with antibacterial and antioxidant activities. The EEP, fractions and sub-fractions showed strong biological activities and were related with phenolic the content compounds contents. 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    Iridio ennui vs the Boltzmann Brains: a novel with equations

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    Iridio Ennui vs The Boltzmann Brains by Mario Daniel Martín is the translation of the second edition of La inevitable resurrección de los cerebros de Boltzmann (The electronic version of the novel is freely downloadable from: https://www.edicionesayarmanot.com/2024/07/cerebros-de-boltzmann-2da-edicion.html ) Ediciones Ayarmanot is now publishing both the second edition in Spanish and the English translation, in collaboration with Encuentro Incorporated of Canberra, Australia.The novel was translated by Kevin Windle and Amalia Milman, in collaboration with the author. This translation was made possible by an Arts ACT Art Activities Grant, awarded by the Canberra City Government

    Pilkington, Dr Roger Windle, (17 Jan. 1915–5 May 2003), author

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    Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene

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    G protein-coupled receptor regulation of gene transcription primarily occurs through the phosphorylation of transcription factors by MAPKs. This requires transduction of an activating signal via scaffold proteins that can ultimately determine the outcome by binding signaling kinases and adapter proteins with effects on the target transcription factor and locus of activation. By investigating these mechanisms, we have elucidated how pituitary gonadotrope cells decode an input GnRH signal into coherent transcriptional output from the LH beta-subunit gene promoter. We show that GnRH activates c-Src and multiple members of the MAPK family, c-Jun NH2-terminal kinase 1/2, p38MAPK, and ERK1/2. Using dominant-negative point mutations and chemical inhibitors, we identified that calcium-dependent proline-rich tyrosine kinase 2 specifically acts as a scaffold for a focal adhesion/cytoskeleton-dependent complex comprised of c-Src, Grb2, and mSos that translocates an ERK-activating signal to the nucleus. The locus of action of ERK was specifically mapped to early growth response-1 (Egr-1) DNA binding sites within the LH beta-subunit gene proximal promoter, which was also activated by p38MAPK, but not c-Jun NH2-terminal kinase 1/2. Egr-1 was confirmed as the transcription factor target of ERK and p38MAPK by blockade of protein expression, transcriptional activity, and DNA binding. We have identified a novel GnRH-activated proline-rich tyrosine kinase 2-dependent ERK-mediated signal transduction pathway that specifically regulates Egr-1 activation of the LH beta-subunit proximal gene promoter, and thus provide insight into the molecular mechanisms required for differential regulation of gonadotropin gene expression
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