7 research outputs found
ISSM_MOOSE_Checklist_RH.pdf
No full textThe checklist item of reactive hypoglycemia systematic review and meta-analysis, based on MOOSE criteria</p
Effectiveness of Participation in Pregnancy Classes to Reduce the Incidence of Obstetric Labor Complications and Cesarean Section
Get PDFObjective : to assess the effectiveness of participation in pregnancy classes to inform such a prenatal program for physicians and midwives, focusing to reduce the incidence of obstetric labor complications and cesarean section.
Methods : This study was done using an analytic observational approach, using a cross-sectional study and consecutive sampling. One hundred and ninety-four participants of this study were women aged 20–35 years who gave birth between January and November 2019 in balarejo sub-district, East Java, Indonesia. The subjects were divided into two groups: participation (four times) and non-participation (less than four times) in the pregnancy classes. The analyzed outcomes are labor complications (prolonged labor, postpartum hemorrhage, postpartum fever, premature rupture of membrane), and cesarean section birth..
Results: The results of this study indicate that participants of pregnancy classes have a significantly lower probability of suffering prolonged labor (OR=0.05, 95% CI=0.01-0.23, p<0.05), postpartum hemorrhage (OR=0.20, 95% CI=0.04-0.95, p<0.05), and postpartum fever (OR=0.13, 95% CI=0.16-1.08, p<0.05) compared with non-participants. Also, participating women have a lower chance of undergoing cesarean section (OR=0.08, 95% CI=0.03-0.21, p<0.05).
Conclusion : The incidence of obstetric labor complications and cesarean section can be effectively reduced by the participation of pregnant woman class
Respiratory Syncytial Virus Maternal Vaccination in Infants below 6 Months of Age: Meta-Analysis of Safety, Immunogenicity, and Efficacy
Get PDFIntroduction: Severe respiratory syncytial virus (RSV) disease
is most prevalent during infancy, particularly in those born
prematurely, who benefit least from maternal antibody
transfers. Maternal immunization is an attractive prevention
leading to vaccine clinical trials. This meta-analysis aimed to
evaluate recent maternal RSV vaccine trials. Methods: Following PRISMA-P guidelines for systematic reviews and
registered at https://www.crd.york.ac.uk/prospero, this
study shortlisted six randomized clinical trials of suitable
quality from four databases. Meta-analysis evaluated vaccine safety, immunogenicity, and efficacy in infants and their
mothers. Results: From random-effects and fixed-effects
meta-analysis between trial and control arms, the maternal post-vaccination geometric antibody (Ab) titers showed
pooled standard mean differences (SMDs [95% CI]) at delivery of (4.14 [2.91–5.37]), (3.95 [2.79–5.11]), and (12.20
[7.76, 16.64]) for RSV neutralizing Ab A, B, and F IgG, respectively. Vaccine administration was more likely than
placebo to cause local pain, erythema, swelling, and systemic myalgia. Furthermore, the Ab levels in infants at birth
showed pooled SMDs of each RSV A (3.9 [2.81–4.99]), RSV B
(1.86 [1.09–2.62]), and RSV F IgG (2.24 [1.24–3.23]). The
overall reduction of RSV-related lower respiratory tract infections and hospitalizations in the first 6 months of life was
52% and 48%, respectively. Conclusions: Not only does
antenatal RSV vaccination look safe and immunogenic in
vaccinated mothers, but it also reliably provides effective
antibody levels in infants and diminishes RSV-related severe
disease in infants under 6 months of age
Evaluating the Phototherapy Practice and Adherence to Guideline in Managing Neonatal Hyperbilirubinemia in an Indonesian Tertiary Referral Hospital
No full textDataset for Manuscript entitled "Evaluating the Phototherapy Practice and Adherence to Guideline in Managing Neonatal Hyperbilirubinemia in an Indonesian Tertiary Referral Hospital"</p
Determinants of neonatal deaths in Indonesia: A national survey data analysis of 10,838 newborns
Get PDFBackground Neonatal mortality is one of the key impediments in achieving global sustainable development goals, especially in lower middle income countries (LMICs). As an LMIC with the highest reported neonatal mortality rate in Southeast Asia, Indonesia faces inequitable distribution of health facilities across the archipelago. Therefore, in this paper, we aim to evaluate the determinants of neonatal mortality rate in Indonesia to search for better strategies to overcome this problem. Methods We conducted an analysis of the 2017 Indonesia Demographic Health Survey dataset of 10,838 live-born infants born from singleton pregnancies in 2017. Using a hierarchical approach, multivariate analysis was conducted to identify potential factors (including socioeconomic, household, and proximate determinants) that contributed to neonatal mortality. Results The lack of participation in postnatal care [odds ratio (OR) = 20.394, p = 0.01)] and delivery complications other than prolonged labour (OR = 2.072, p = 0.02) were the maternal factors that significantly associated with increased risk of neonatal death. Regarding neonatal factors, low-birth-weight infants appeared to be more vulnerable to neonatal death (OR = 12.489, p = 0.01). Conclusion Low participation in postnatal care, development of labour complications, and low birth weight were associated with higher neonatal mortality. It implies that in a limited resource and geographically challenging country such as Indonesia, improving the quality and optimizing services of public hospitals with equitable distribution of quality health care services in all regions should be prioritized in the efforts of reducing neonatal mortality rate
Kramer Score, an Evidence of Its Use in Accordance with Indonesian Hyperbilirubinemia Published Guideline
Get PDFBackground: In some hospitals in low/middle-income countries, methods to determine the bilirubin level in newborn infants are unavailable and based on a clinical evaluation, namely a clinical score designed by Kramer. In this study, we evaluated if this score can be used to identify those infants that need phototherapy. Method: Infants admitted between November 2018 and June 2019 to three hospitals in Surabaya, Indonesia were included. The jaundice intensity was scored using the Kramer score. Blood was sampled for total serum bilirubin (TSB) measurement. The infants were categorized into Treatment Needed (TN) group when treatment with phototherapy was indicated and the No Treatment Needed (NTN) group when phototherapy was not indicated, based on the Indonesian Guideline for hyperbilirubinemia. Result: A total of 280 infants with a mean birth weight of 2744.6 +/- 685.8 g and a gestational age of 37.3 +/- 2.3 weeks were included. Twenty-seven of 113 (24%) infants with Kramer score 2 needed phototherapy, compared with 41 of 90 (46%) infants with score 3 and 20 of 28 (71%) of infants with score 4. The percentage of infants that needed phototherapy was higher with decreasing gestational age. Conclusion: The Kramer score is an invalid method to distinguish between those infants needing phototherapy and those infants where this treatment is not indicated.</p
Value relevance do nível de disclosure das combinações de negócios e do goodwill reconhecido nas empresas brasileiras
Get PDFTese (doutorado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico, Programa de Pós-Graduação em Administração, Florianópolis, 2015.O Brasil convergiu suas normas contábeis aos padrões internacionais do International Accounting Standards Board (IASB). Um dos eventos relevantes nesse contexto foi a emissão do pronunciamento contábil CPC-15 tratando das combinações de negócios, cujos procedimentos estão alinhados à norma IFRS 3 do IASB. A referida norma internacional é considerada um dos tópicos mais complexos atinentes às normas do IASB, que exige intensa utilização do valor justo (BABOUKARDOS; RIMMEL, 2014). A complexidade em torno da norma engloba o disclosure das informações relativas às combinações de negócios e do goodwill reconhecido nessas transações, os comentários enviados ao IASB acerca da pós-implementação da IFRS 3 revisada confirmam essas dificuldades. Nesse ambiente, Schipper, (2007); Leuz e Wysocki, 2008; Tsalavoutas e Dionysiou (2014) e Baboukardos e Rimmel (2014) discorrem que existem poucos estudos tratando sobre o disclosure obrigatório. Este trabalho tem como objetivo verificar o value relevance do nível de disclosure das combinações de negócios e do ágio por expectativa de rentabilidade futura (goodwill) reconhecido nas empresas brasileiras. O levantamento das combinações de negócios foi feito por meio dos fatos relevantes divulgados no site da Comissão de Valores Mobiliários (CVM). A amostra de pesquisa é composta pelas empresas de capital aberto brasileiras que realizaram alguma combinação de negócio no período entre 2010 e 2013 e tiveram o papel de adquirente na transação, perfazendo uma amostra de 202 observações. Para mensurar o nível de disclosure, elaborou-se uma métrica a partir do CPC-15 R1 (2011) realizando a abertura de alguns itens de divulgação a fim de alcançar um maior detalhamento das informações. A coleta dos dados foi por meio das notas explicativas integrantes das Demonstrações Financeiras Padronizadas (DFPs) anuais disponibilizadas no website da Bolsa de Valores, Mercadorias e Futuros de São Paulo (BM&BOVESPA). Através de um modelo de regressão múltipla, visando avaliar o value relevance do nível de disclosure e do goodwill reconhecido, foram adotadas três abordagens relativas à7variável dependente preço das ações, quais sejam: abordagem 1) preço da ação três meses após o encerramento do exercício social; abordagem 2) preço da ação no encerramento do exercício social; e; abordagem 3) preço da ação imediatamente após a publicação das DFPs no site da BM&BOVESPA. Os resultados demonstraram que o nível de disclosure das combinações de negócios é positivamente e significativamente relacionado com o preço das ações das empresas brasileiras, nas três abordagens utilizadas. Já o goodwill reconhecido nas combinações de negócios, embora em média apresente um valor significativo na transação, não demonstrou significância estatística para explicar o preço das ações em nenhuma das abordagens utilizadas. Vale destacar também que a média do nível de disclosure das combinações de negócios analisadas foi muito baixa, não sendo suficiente para proporcionar uma visão dos fatores que integram o goodwill adquirido.Abstract : Brazil has harmonized its accounting rules with those set forth by the International Accounting Standards Board (IASB). An event of particular note during this process was the creation of the accounting pronouncement CPC-15, which concerns business combinations, detailing procedures in accordance with the IASB standard IFRS 3. Considered one of the most complex topics within the realm of IASB rules, this standard espouses extensive use of fair value measurement (BABOUKARDOS; RIMMEL, 2014). A share of the complexity surrounding the rule encompasses the disclosure of information concerning business combinations and the goodwill recognized in such transactions, the commentary provided to the IASB in respect to the post-implementation review of IFRS 3 attests to these difficulties. Upon addressing these circumstances, Schipper (2007), Leuz and Wysocki 2008, Tsalavoutas and Dionysiou (2014), and Baboukardos and Rimmel (2014) point to the existence of few studies on mandatory disclosure. The objective of this study is to examine the value relevance of the disclosure level of business combination and goodwill recognized by Brazilian companies. The business combinations that took place during this period were identified by way of details concerning the same disclosed by the Comissão de Valores Mobiliários (CVM) website. The research sample is composed of the publically traded Brazilian companies that underwent any type of business combinations, as the acquiring entity, between 2010 and 2013, which yielded a total sample of 202 observations. To measure the disclosure level of each, a gauging device was created using CPC-15 R1 (2011) as its base, delving into certain disclosure items in order to render a greater level of detail. Data collection was carried out using the footnotes to the annual standardized financial statements (DFP) available on the São Paulo Stock Exchange (BM&BOVESPA) website. Using a multiple regression model and seeking to evaluate the value relevance of the disclosure level and recognized goodwill, the following three approaches to the stock price the dependent variable, were adopted: 1) the stock price three months9following the balance sheet date; 2) the stock price at the balance sheet date; and 3) the stock price immediately after the publication of the financial statements on the BM&BOVESPA website. The results revealed that disclosure levels in business combinations is positively and significantly associated to the stock price of Brazilian companies, as shown by each of the three approaches employed in the study. As to the recognition of goodwill during business combinations, despite the fact that it represents a significant share of the value of the transaction, no statistical significance explaining stock price behavior was found by way of any of the approaches employed. It also bears mentioning that the disclosure level in regard to the business combinations in question was quite low, and thusly it did not allow for insight into the factors that result in the goodwill acquired
