1,721,624 research outputs found
Brain evolution, language, and psychopathology in schizophrenia
No full textThis book provides a comprehensive review of new developments in the study of language processing and related neural networks in schizophrenia by addressing
the complex link between psychopathology, language and evolution at different levels of analysis. Psychopathological symptoms in schizophrenia are mainly characterized by thought and language disorders, which
are strictly intertwined. In particular, language is the distinctive dimension of human beings and is ontologically
related to brain development. Although normal at the levels of segmental phonology and morphological
organization, the speech of patients suffering from schizophrenia is often characterized by flattened intonation
and word-finding difficulties. Furthermore, research suggests that the superior temporal gyrus and specific
prefrontal areas which support language in humans are altered in people with schizophrenia. Brambilla and Marini bring together international contributors to explore the link between brain evolution
and the psychopathological features of schizophrenia, with a focus on language and its neural underpinnings.
Divided into three sections the book covers: • brain evolution and language phylogenesis; • brain abnormalities in schizophrenia; • psychopathology and schizophrenia. This theoretical approach will appeal to professionals including clinical psychologists, cognitive neuroscientists, neuropsychiatrists, neuropsychologists, neurolinguists,
and researchers considering the links between brain evolution, language and psychopathology in schizophrenia
Limited evidence that antipsychotic drug treatment is associated with reduced brain volume
No full textComment on Moncrieff J, Leo J. "A systematic review of the effects of antipsychotic drugs on brain volume" Psychol Med. 2010 Sep;40(9):1409-22
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Induction of general anaesthesia by rapid injection of propofol and dexmedetomidine or propofol and buthorphanol: cardiopulmonary and echocardiographic parameters in unpremedicated dogs
No full text2011 The Authors. Veterinary Anaesthesia and Analgesia
20 2011 Association of Veterinary Anaesthetists and the American College of Veterinary Anesthesiologists, 38, 1–35 Induction of general anaesthesia by rapid
injection of propofol and dexmedetomidine
or propofol and butorphanol:
cardiopulmonary and echocardiographic
parameters in unpremedicated dogs
G Ravasio, L Borghi, D Fonda, P Brambilla, V Bronzo,
J Cincotti & C Locatelli
Universita` degli Studi di Milano, Facolta` di Medicina
Veterinaria di Milano, via Celoria 10, 20133 (MI) Italy
The aim was to compare quality of induction,
echocardiographic and cardiopulmonary effects of
two different general anaesthesia induction protocols.
Twelve dogs (ASA I-II) were assigned randomly
into two groups. Both groups received a rapid bolus
of propofol (2.2 mg kg)1 IV) immediately followed
by a rapid bolus of dexmedetomidine 3 lg kg)1 IV
(group A) or butorphanol 0MAP, SAP (NIBP) were recorded and 2, 5, 10, 15,
20 minutes after drug administration. Induction
quality, intubation time, additional propofol dose to
achieve intubation, sedation score (Fernandez et al.
2005) and adverse effects were recorded. Echocardiogram
was performed at baseline and immediately
after tracheal intubation. Data were analyzed using
repeated measures ANOVA and Wilcoxon test
(p < 0.05).
Induction quality, intubation time (A: 75 ± 25,
B: 145 ± 66.8 seconds) were statistically different
between groups, HR was statistically lower in group
A compared to baseline (62 ± 23; 101 ± 23), fR
was not statistically different between groups but
lower than baseline in group A, NIBP was statistically
higher in group A and lower in group B
compared to baseline. Body temperature, SpO2,
PE¢CO2 were not statistically different. No apnoea
(>30 seconds) or emesis were recorded. Five group
B dogs required additional propofol (1.1 ± 0.7
mg kg)1 IV) to achieve tracheal intubation. Left
ventricular end-diastolic diameter was statistically
lower in group B and statistically higher in group A
compared to baseline. Cardiac output decrease was
18.5% in group A and 24.4% in group B.
Quality of induction was better in group A.
Echocardiographic parameters varied compared to
baseline in both groups but remained within normal
ranges for adult dogs (Cornell et al. 2004).
References: Fernandez JG, Parodi E, Garcia P et al.
(2005) Clinical action of subarachnoid sevoflurane
in vivo: a study in dogs. Brit J Anaesth 95(4), 530–
534.
Cornell CC, Kittleson MD, Della Torre P et al.
(2004) Allometric scaling of M-Mode cardiac measurements
in normal adult dogs. J Vet Intern med
18(3), 311–321..4 mg kg)1 IV (group B)
administered by a blinded operator. Baseline HR
Updating of CMOS reliability
No full textUpdated results of massive life tests on CMOS are reported. The failure rate derived from laboratory conditions is extrapolated for long life use and compared with field results. Failure mechanism distribution is also reported
Body mass index (BMI) ed early adiposity rebound (EAR) : due parametri utili nella valutazione della crescita ponderale del bambino
No full text- …
