1,870 research outputs found
RIC-HSCT for MF/SS
No full textAdvanced-stage mycosis fungoides and Sezary syndrome (MF/SS) have a poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT), particularly using a reduced-intensity conditioning (RIC) regimen, is a promising treatment for advanced-stage MF/SS. We performed RIC-HSCT in nine patients with advanced MF/SS. With a median follow-up period of 954days after HSCT, the estimated 3-year overall survival was 85.7% (95% confidence interval, 33.4-97.9%) with no non-relapse mortality. Five patients relapsed after RIC-HSCT; however, in four patients whose relapse was detected only from the skin, persistent complete response was achieved in one patient, and the disease was manageable in other three patients by the tapering of immunosuppressants and donor lymphocyte infusion, suggesting that graft-versus-lymphoma effect and "down-staging" effect from advanced stage to early stage by HSCT improve the prognosis of advanced-stage MF/SS. These results suggest that RIC-HSCT is an effective treatment for advanced MF/SS
Preparation of mono-sized epoxy/MF microcapsulesin the appearance of polyvinyl alcohol as co-emulsifier
No full textFor epoxy microcapsules embedded in concrete as mechanic-triggered self-healing adhesive, globular shape with uniform size is the basic requirement to ensure the solid shell broken and the liquid core released at a designed stress. In this paper, monodispersed melamine\u96formaldehyde (MF) resin-walled epoxy E-51 microcapsules were successfully fabricated in an in situ polycondensation process, in which a certain amount of polyvinyl alcohol (PVA) solution was added as coemulsifier to control the microcapsules\u92 shape and size. Detail investigation shows, with the cooperation of PVA, the microcapsule morphologies and size distribution were ease to be adjusted by the parameters such as emulsifying agents, agitation rate, pH value and acidification time
ACT Family Violence Intervention Program review
No full textThis paper reports on a review of the Australian Capital Territory’s Family Violence Intervention Program, which provides an interagency response to family violence matters.
The scope of the review was to analyse the program’s activities and outcomes using 2007–08 data provided by participating agencies, supported by in-depth interviews with key stakeholders including victims whose matters had been finalised in court. After the completion of this report, additional data from 2008–09 and 2009–10 was made available by some Family Violence Intervention Program (FVIP) participating agencies. Although not within the scope of this evaluation, these data pointed to some preliminary improvements in the FVIP
NF membrane fouling by aluminum and iron coagulant residuals after coagulation-MF pretreatment
No full textThe effects of coagulant residuals on fouling of a nanofiltration (NF) membrane were investigated. Experiments were carried out with a laboratory-scale microfiltration (MF)-NF setup and a pilot MF-NF plant. In the laboratory-scale experiments, NF feed water was pretreated with poly-aluminum chloride (PACl) or alum followed by MF. NF membrane permeability declined when the feed water contained residual aluminum at 18 μg/L or more, but not when it was lower than 9 μg/L. When pretreated with ferric chloride, no substantial decline of NF membrane permeability was observed: residual iron did not affect the permeability. When SiO2 was added to the water before the pretreatment with PACl, the NF membrane permeability declined at about double the speed. Thermodynamic calculations and elemental analysis of foulants recovered from the membranes indicated that the majority of inorganic foulants were compounds composed of aluminum, silicate, and possibly potassium. In the pilot plant, NF feed was pretreated by PACl. Transmembrane pressure for NF doubled over 4.5 months of operation. Although the aluminum concentration in the NF feed was not high (30 μg/L), analysis of membrane foulants revealed excessive accumulation of aluminum and silicate, also suggesting that aluminum residuals caused the membrane fouling by alumino-silicates or aluminum hydroxide
Undiagnosed Epileptic Case Since Childhood of Sturge-Weber Syndrome: First Case Report from Somalia
No full textSaid Abdi Mohamed,1 Nor Osman Sidow,1,2 Bakar Ali Adam,1 Mohamed Sheikh Hassan,1,3 Abdiwahid Ahmed Ibrahim,1 Mohamed Farah Osman,1 Abdulkadir Ahmed,1 Abdullahi Ali Roble4 1Department of Neurology, Mogadishu-Somalia Turkey Recep Tayyip Erdoğan Training and Research Hospital, Mogadishu, Somalia; 2Faculty of Medicine and Surgery, Jazeera University, Mogadishu, Somalia; 3Faculty of Medicine and Surgery, Mogadishu University, Mogadishu, Somalia; 4Department of Ophthalmology, Mogadishu-Somalia Turkey Recep Tayyip Erdoğan Training and Research Hospital, Mogadishu, SomaliaCorrespondence: Nor Osman Sidow, Tel +252618300616, Email [email protected]: Sturge-Weber syndrome is a rare, sporadic, progressive neurocutaneous condition that presents with congenital hamartomatous malformations, epilepsy, and a variety of facial symptoms. We discussed a rare case of an eighteen-year-old female child who came to our neurology department with status epilepticus, mental impairment, and a port-wine in the lateral left side of her face. We diagnosed Sturge-Weber syndrome after a thorough neurological and radiological evaluation. The purpose of presenting this case is to illustrate both the characteristic presentation and the complications associated with managing Sturge-Weber syndrome.Keywords: sturge-weber, seizure, port-win
Impact Of Heat Treatment On Weight Loss During Combustion Of Laminated Veneer Lumber (LVL)
No full textThis study was performed to determine the effects of heat treatment on weight loss during combustion of the laminated wood materials produced from Oriental beech (Fagus orientalis L.), scotch pine (Pinus sylvestris L.), sessile oak (Quercus petraea L.), and poplar (Populus nigra L.) veneers bonded with PVAc-D-4, PUR and MF adhesives. For this aim, the weight loss during combustion of the test samples was determined according to ASTM E 160-50. The results of this study indicated that the weight loss percentage was the highest in poplar wood (89.17%), PVAc-D-4 adhesive (89.79%) and control samples (88.69%). In the interaction of the wood materials and type of adhesive, the highest value was measured in poplar+PUR (90.93%), interaction of the wood materials and heat treatment in poplar + control samples (90.87%), in the interaction of the type of adhesive and heat treatment in PVAc-D-4 + 185 degrees C (91.10%). In the interaction of the wood material, type of adhesive and heat treatment temperature, the highest value was determined in laminated control poplar samples with PUR adhesive (93%), while the lowest in laminated scotch pine samples with MF and heat-treated at 185 degrees C (81.83%). The use of laminated and heat-treated wood material in places where in high risk of fire, impregnation of wood material with fire-retardant compounds can be suggested.Scientific and Technological Research Council of Turkey, (TUBITAK), TOVAG Project [110O020]This study is a portion of the Ph.D thesis prepared by Osman Percin, Institute of Science and Technology, Gazi University, Ankara, Turkey. This study also, is a portion of the Project that was supported by The Scientific and Technological Research Council of Turkey, (TUBITAK), TOVAG Project Number: 110O020
Finite element modeling and experimental studies on mixed mode-I/III fracture specimens
No full textIn this study, finite element modeling and experimental studies on a mode-I/III specimen similar to the compact tension specimen are presented. By using bolts, the specimen is attached to two loading apparatus that allow different levels of mode-I/III loading by changing the loading holes. Specimens having two different thicknesses are analyzed and tested. Modeling, meshing and the solution of the problem involving the whole assembly, i.e., loading devices, bolts and the specimen, with contact mechanics are performed using ANSYS (TM). Then, the mode-I/III specimen is analyzed separately using a submodeling approach, in which three-dimensional enriched finite elements are used in FRAC3D solver to calculate the resulting stress intensity factors along the crack front. In all of the analyses, it is clearly shown that although the loading is in the mode-I and III directions, mode-II stress intensity factors coupled with mode-III are also generated due to rotational relative deformations of crack surfaces. The results show that the mode-II stress intensity factors change sign along the crack front and their magnitudes are close to the mode-III stress intensity factors. It is also seen that magnitudes of the mode-III stress intensity factors do not vary much along the crack front. Fracture experiments also performed and, using the stress intensity factors from the analyses and crack paths and surfaces are shown
Study of Radioclinical and Risk Factors of Cerebral Venous Thrombosis: A Retrospective Analysis of Patients Presenting to a Tertiary Hospital in Mogadishu, Somalia
No full textBakar Ali Adam,1,2 Ahmed Adam Osman,3 Mohamed Sheikh Hassan,1,2 Nor Osman Sidow,1 Mohamed Farah Osman Hidig,1 Abdulkadir Ahmed Mohamed,1 Abdiwahid Ahmed Ibrahim,1 Said Abdi Mohamed,1 Yahye Garad Mohamed,3 Said Abdirahman Ahmed,4 Mohamed Osman Omar Jeele,5 Mohamed Omar Hassan4 1Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia; 2Faculty of Medicine and Surgery, Mogadishu University, Mogadishu, Somalia; 3Department of Radiology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia; 4Department of Cardiology, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, Somalia; 5Department of Internal Medicine, Mogadishu Somali Turkish Training and Research Hospital, Mogadishu, SomaliaCorrespondence: Bakar Ali Adam, Email [email protected]: Cerebral venous thrombosis (CVT) is a rare but potentially life-threatening condition characterized by the formation of a blood clot in the dural venous sinuses or cerebral veins. CVT presents a diverse array of clinical symptoms, making its diagnosis challenging. Understanding regional variations and specific risk factors associated with CVT is crucial, especially in low-resource settings like Somalia, where epidemiological data is limited and healthcare resources are scarce.Objective: This study aims to investigate the clinical and risk factors associated with CVT in patients presenting to Mogadishu Somali-Turkey Recep Tayyip Erdogan Research and Training Hospital, a tertiary hospital in Mogadishu, Somalia.Methods: We conducted a retrospective observational study involving 68 patients diagnosed with CVT between January 2019 and December 2023. Data included demographic information, clinical presentations, risk factors, and anatomical thrombosis locations. Descriptive statistics and chi-square tests were used for analysis.Results: The majority of patients were female (86.76%) and aged 20– 40 years (86.76%). Significant risk factors included the postpartum period (77.94%) and pregnancy, with statistical analysis showing strong associations between CVT and the postpartum period (χ² = 62.96, p < 0.0001) and pregnancy (χ² = 5.21, p = 0.022). Postpartum CVT was linked to thrombosis location (p = 0.025). Headache was the predominant symptom (98.53%), followed by altered mental status (83.82%), focal motor deficits (80.88%), and seizures (70.59%). The superior sagittal sinus was the most commonly involved site (57.35%).Conclusion: This study emphasizes the postpartum period as a significant risk factor for CVT in Somalia and highlights the need for clinical vigilance and early intervention strategies. Larger, multicenter studies are needed to validate these findings.Keywords: cerebral venous thrombosis, CVT, postpartum, pregnancy, risk factors, Somalia, regional stud
Correction Factor on Dynamic Force in a Marsh Funnel Test for Tunneling
No full textThis paper presents an improvement on a previous model for predicting the Marsh funnel (MF) test that is used in slurry shield tunneling for evaluating the rheological properties of bentonite slurries. The improvement focuses on the prediction of the dynamic part for fluids with small MF times. The velocity profile of the Herschel-Bulkley fluid in a laminar pipe flow condition is first investigated and a correction factor is introduced in the improved model. Comparisons of results from experiments and calculations with the previous model confirm the improved performance over the existing model. The rheological parameters obtained from the improved model show good resemblance to those obtained from a laboratory viscometer. The work also provides a reference to similar applications such as fluid transportation through pipelines where dynamic pressure dominates and therefore should be correctly predicted considering its velocity profile in a laminar condition.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Offshore and Dredging Engineerin
Thermal analysis of a miniature magnetic fluid seal installed in an implantable rotary pump
No full textThe capacity of a magnetic fluid (MF) seal is decreased by increased MF temperature. A cooling system for MF is limited in a miniature MF seal installed in an implantable rotary pump. MF temperature in an MF seal installed in an implantable rotary pump was studied. The temperature of MF in a rotary pump was measured in vitro. Also, steady-state thermal analyses were conducted for an implantable rotary pump model. The results showed that (1) the decrease in magnetization of an MF due to increased temperature is negligible when the heat transfer coefficient of the seal housing is greater than 500 W/(m2·K) and (2) the increased temperature is mainly due to heat flux from the motor, and the magnitude of temperature increase due to viscous friction in the MF is low. In conclusion, an MF seal can be used in an implantable rotary pump from the standpoint of heat characteristics
- …
