125 research outputs found
Nitrate transport and signalling
No full textTimes Cited: 134 Miller, Anthony/B-5139-2008; ORSEL, Mathilde/C-5435-2009 Miller, Anthony/0000-0003-0572-7607; ORSEL, Mathilde/0000-0002-0837-6796 International Symposium on Nitrogen Nutrition in Plants Jul 27-31, 2007 Lancaster Univ, Lancaster, ENGLAND 146International audiencePhysiological measurements of nitrate (NO3-) uptake by roots have defined two systems of high and low affinity uptake. In Arabidopsis, genes encoding both of these two uptake systems have been identified. Most is known about the high affinity transport system (HATS) and its regulation and yet measurements of soil NO3- show that it is more often available in the low affinity range above 1 mM concentration. Several different regulatory mechanisms have been identified for AtNRT2.1, one of the membrane transporters encoding HATS; these include feedback regulation of expression, a second component protein requirement for membrane targeting and phosphorylation, possibly leading to degradation of the protein. These various changes in the protein may be important for a second function in sensing NO3- availability at the surface of the root. Another transporter protein, AtNRT1.1 also has a role in NO3- sensing that, like AtNRT2.1, is independent of their transport function. From the range of concentrations present in the soil it is proposed that the NO3- -inducible part of HATS functions chiefly as a sensor for root NO3- availability. Two other key NO3- transport steps for efficient nitrogen use by crops, efflux across membranes and vacuolar storage and remobilization, are discussed. Genes encoding vacuolar transporters have been isolated and these are important for manipulating storage pools in crops, but the efflux system is yet to be identified. Consideration is given to how well our molecular and physiological knowledge can be integrated as well to some key questions and opportunities for the future
The Arabidopsis ATNRT2.7 nitrate transporter controls nitrate content in seeds
No full textTimes Cited: 72 Miller, Anthony/B-5139-2008; ORSEL, Mathilde/C-5435-2009; Chardon, Fabien/G-4826-2013 Miller, Anthony/0000-0003-0572-7607; ORSEL, Mathilde/0000-0002-0837-6796; Chardon, Fabien/0000-0001-7909-3884 83International audienceIn higher plants, nitrate is taken up by root cells where Arabidopsis thaliana NITRATE TRANSPORTER2.1 (ATNRT2.1) chiefly acts as the high-affinity nitrate uptake system. Nitrate taken up by the roots can then be translocated from the root to the leaves and the seeds. In this work, the function of the ATNRT2.7 gene, one of the seven members of the NRT2 family in Arabidopsis, was investigated. High expression of the gene was detected in reproductive organs and peaked in dry seeds. beta-Glucuronidase or green fluorescent protein reporter gene expression driven by the ATNRT2.7 promoter confirmed this organ specificity. We assessed the capacity of ATNRT2.7 to transport nitrate in Xenopus laevis oocytes or when it is expressed ectopically in mutant plants deficient in nitrate transport. We measured the impact of an ATNRT2.7 mutation and found no difference from the wild type during vegetative development. By contrast, seed nitrate content was affected by overexpression of ATNRT2.7 or a mutation in the gene. Finally, we showed that this nitrate transporter protein was localized to the vacuolar membrane. Our results demonstrate that ATNRT2.7 plays a specific role in nitrate accumulation in the seed
Reading Mathilde de La Mole in the Age of Protest Feminism
No full textPublishedArticleThis article analyses the critical reception, over time, of Stendhal’s unconventional heroines, attempting to identify and challenge some of the assumptions and prejudices that have been active in the extensive secondary literature devoted to the author. It focuses on critical responses to Mathilde de La Mole, with a view to showing how the attitudes of readers of Le Rouge et le Noir have changed over time, and in order to make a case for their further alteration. Stendhal’s early critics judged her character as lacking in verisimilitude; some celebrated the implausible aspects of her character, while others saw them as literary shortcomings. While such criticisms certainly conveyed an implicit moral judgement, later critics focused far more explicitly on what they perceived as Mathilde’s moral deficiencies, more specifically her failings as a woman and a person; there is also a small but growing number of readers and critics who have read her moral character in a highly favourable light. It will be argued in this essay that different evaluations of Mathilde’s character are authorized by the plural perspectives offered by the text
Editorial
No full textAs with our number 41 tenth anniversary issue, we publish here a full list of tables of contents, an author index and an article-title index covering the past ten years of the BMS. We analyze the contents of the articles using two different methods. This material constitutes the first "Ongoing Research" report, "Correspondence & Co-Word Analysis of Ten Years of BMS Articles (1993-2003)", by Karl M. van Meter, Philippe Cibois and Mathilde de Saint Léger. This issue also includes two research a..
Teste projetivo sonoro
No full textPartindo da influência que a música tem sobre as emoções humanas, o autor idealizou uma nova maneira de avaliação psicológica das pessoas cegas, utilizando como estímulo, três melodias inéditas. Para testar esta hipótese, submeteu um grupo de adolescentes sem problemas visuais ao Teste Projetivo Sonoro. Este teste consiste em solicitar dos sujeitos que elaborem três estórias, cada uma delas relacionada com uma das músicas do teste. A avaliação psicológica resulta da interpretação das estórias elaboradas, como se fossem sonhos. Para esta interpretação, o autor propõe uma série de perguntas que tem como objetivo facilitar a associação da estória elaborada com a vida do sujeito. Esta primeira aplicação do Teste Projetivo Sonoro permitiu verificar que as estórias elaboradas tem mais relação com a vida da pessoa do que com a música utilizada como estímulo. Assim sendo, a música aparece como estímulo desencadeante de um processo de projeção que funcionou a contento na aplicação em pessoas com visão normal. Para verificar se o Teste Projetivo Sonoro desencadearia os mesmos processos de projeção, o autor aplicou em três cegos congênitos e em três cegos adquiridos, com resultados igualmente satisfatórios, ou seja, as estórias elaboradas pelas pessoas cegas mostraram muito mais relação com a vida delas do que com as músicas. Portanto o autor afirma que o Teste Projetivo Sonoro se configura como um promissor instrumento clínico na avaliação psicológica, tanto de pessoas cegas como de pessoas com visão normalFrom the of point of view of the influence music has on human emotions, the author idealized a new way of psychological evaluation of blind people using three unknown melodies as stimulus. In order to test this hypothesis, he submitted a group of adolescents with no visual problems to the Projective Sound Test. This test consists of asking the subjects to elaborate three stories, each one in accordance to the musics in the test. The psychological evaluation results from the interpretation of the stories elaborated as if they were dreams. ln order to interpret these stories, the author proposes a series of questions to facilitate the association of the application of the Projective Sound Test allowed the verification that the elaborated stories are more m agreement to the life of the person than to the music utilized as stimulus. Thus, the music is presented as stimulus which starts a process of projection which has worked satisfactorily with normal sighted people. In order to verify if the Projective Sound Test would start the same projective processes, the author applied it to three born blind people and to three acquired blind, coming to equally satisfactory results, that is, the stories elaborated by the blind people showed much more relation to their lives than to the musics. Considering this result, the author affirms that the Projective Sound Test configurates a promissing clinical instrument in the psychological evaluation not only of normal sighted people but also of the blin
La migration des œuvres françaises en Asie
No full text© 2017, © The Author(s) 2017. Le présent article propose d’examiner la problématique de la migration des œuvres de la littérature française vers le continent d’Asie. Il tentera d’établir l’origine de cette migration, le parcours migratoire des œuvres ainsi que les conditions de leur accueil dans les pays asiatiques notamment en Chine et au Japon. Parmi les nombreux aspects reliés au transfert des œuvres vers leurs nouveaux lectorats, le rôle de vecteur que joue la traduction sera analysé. Sera aussi mis en relief le rôle de tremplin et d’intermédiaire du Japon dans l’accomplissement du transfert des œuvres françaises. Enfin Madame Chrysanthème tout comme La Dame aux camélias sera étudiée sous l’angle de leur rencontre avec la littérature locale
Correction to: Idelalisib treatment prior to allogeneic stem cell transplantation for patients with chronic lymphocytic leukemia: a report from the EBMT chronic malignancies working party (Bone Marrow Transplantation, (2021), 56, 3, (605-613), 10.1038/s41409-020-01069-w)
No full textThe Idelalisib treatment prior to allogeneic stem cell transplantation for patients with chronic lymphocytic leukemia: a report from the EBMT chronic malignancies working party, written by Johannes Schetelig, Patrice Chevallier, Michel van Gelder, Jennifer Hoek, Olivier Hermine, Ronjon Chakraverty, Paul Browne, Noel Milpied, Michele Malagola, Gerard Socié, Julio Delgado, Eric Deconinck, Ghandi Damaj, Sebastian Maury, Dietrich Beelen, Stéphanie Nguyen Quoc, Paneesha Shankara, Arne Brecht, Jiri Mayer, Mathilde Hunault-Berger, Jörg Bittenbring, Catherine Thieblemont, Stéphane Lepretre, Henning Baldauf, Liesbeth C. de Wreede, Olivier Tournilhac, Ibrahim Yakoub-Agha, Nicolaus Kröger, Peter Dreger was originally published Online First without Open Access. After publication in volume 56, issue 3, page 605–613 the author decided to opt for Open Choice and to make the article an Open Access publication. Therefore, the copyright of the article has been changed to © The Author(s) 2020 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/ licenses/by/4.0. Open access funding enabled and organized by Projekt DEAL
Mitigation of DESI fiber assignment incompleteness effect on two-point clustering with small angular scale truncated estimators
No full textM. Pinon et al. -- Dark energy spectroscopic instrument (DESI) survey year 1 resultsWe present a method to mitigate the effects of fiber assignment incompleteness in two-point power spectrum and correlation function measurements from galaxy spectroscopic surveys, by truncating small angular scales from estimators. We derive the corresponding modified correlation function and power spectrum windows to account for the small angular scale truncation in the theory prediction. We validate this approach on simulations reproducing the Dark Energy Spectroscopic Instrument (DESI) Data Release 1 (DR1) with and without fiber assignment. We show that we recover unbiased cosmological constraints using small angular scale truncated estimators from simulations with fiber assignment incompleteness, with respect to standard estimators from complete simulations. Additionally, we present an approach to remove the sensitivity of the fits to high k modes in the theoretical power spectrum, by applying a transformation to the data vector and window matrix. We find that our method efficiently mitigates the effect of fiber assignment incompleteness in two-point correlation function and power spectrum measurements, at low computational cost and with little statistical loss.This material is based upon work supported by the U.S. Department of Energy (DOE), Office of Science, Office of High-Energy Physics, under Contract No. DE-AC02-05CH11231, and by the National Energy Research Scientific Computing Center, a DOE Office of Science User Facility under the same contract. Additional support for DESI was provided by the U.S. National Science Foundation (NSF), Division of Astronomical Sciences under Contract No. AST-0950945 to the NSF National Optical-Infrared Astronomy Research Laboratory; the Science and Technology Facilities Council of the United Kingdom; the Gordon and Betty Moore Foundation; the Heising-Simons Foundation; the French Alternative Energies and Atomic Energy Commission (CEA); the National Council of Humanities, Science and Technology of Mexico (CONAHCYT); the Ministry of Science and Innovation of Spain (MICINN), and by the DESI Member Institutions: https://www.desi.lbl.gov/collaborating-institutions. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the U.S. National Science Foundation, the U.S. Department of Energy, or any of the listed funding agencies. The authors are honored to be permitted to conduct scientific research on Iolkam Du’ag (Kitt Peak), a mountain with particular significance to the Tohono O’odham Nation.Peer reviewe
Additional file 1: of Cell wall dynamics during apple development and storage involves hemicellulose modifications and related expressed genes
No full textDifferentially expressed genes during apple development and ripening. Expression data for differentially expressed genes between 60DAF and 2 M, displaying similar expression patterns for the eight genotypes (H074, H097, I016, I062, I095, V034, V083, W029) in both plots (PH and P12). Genes relatively more expressed during early fruit development (60 and 110 DAF) or during fruit maturation and cold storage (H, 1 M and 2 M) were respectively grouped in cluster A and B. Five time points are 60 days after flowering (60 DAF), 110 days after flowering (110 DAF), harvest (H), 1 month and 2 months of cold storage (1 M and 2 M). (XLSX 4945 kb
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