131,073 research outputs found

    Orbach urges renewed commitment to nuclear physics work

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    According to US Office of Science director Raymond Orbach, the Energy Department plans to issue a background paper in the coming months that will make the case for supporting the department's accelerator program for nuclear physics research (1 page)

    Ribosomal DNA representation in the Orbach-Sachs and Vollmer-Yanofsky N. crassa cosmid libraries

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    We have been employing the Orbach-Sachs (1991 Fungal Genetics Newsl. 38:97) and Vollmer-Yanofsky (Vollmer and Yanofsky 1986 Proc. Natl. Acad. Sci. USA 83:4869-4873) N. crassa cosmid libraries (obtained from the Fungal Genetics Stock Center) in subtractive hybridization experiments designed to identify genes induced under conditions of oxidative stress. Because cosmids containing the 17S and 26S ribosomal RNA genes produce false positives in these experiments, it was necessary for us to identify cosmids in the Orbach-Sachs containing these genes

    Copulation rate declines with mating group size in dusky dolphins (lagenorhynchus obscurus)

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    Males in polygamous species often engage in intrasexual competition for mates. If females actively evade mating attempts,itmay benefit malestocooperate to restrict female movement, ashas been foundinsome mammals. Wetested ifmale dusky dolphins (Lagenorhynchus obscurus (Gray, 1828)) cooperate or compete during group mating chases. If they cooperate, then the per-male probability of copulating should increase with group size; if they compete, then the probability should decrease. We followed mating groups by boat during the breeding season (October 2013 – January 2014) off Kaikoura, New Zealand. The copulation rate per male decreased with increasing group size and with the number of noncopulating males in proximity to a copulating female. Male dusky dolphins have multiple mates and appear to use sperm and exploitative scramble competition. Males may remain in mating groups despite competition because there are alliances within the groups, they are unable to exclude rivals from joining a group, the time and energy costs of searching for unescorted females exceed the costs of reduced mating opportunities in a group, they receive other direct or indirect benefits that offset the costs of reduced mating opportunities, or they are in the group largely for social learning rather than procreation

    Neonatal soft tissue sarcomas.

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    Soft tissue tumors in very young children pose diagnostic and therapeutic challenges. Vascular tumors are the most prevalent soft tissue neoplasms in the neonatal period. They are generally benign tumors, but may exhibit aggressive behaviour and cause life-threatening complications. Fibroblastic tumors of intermediate prognosis, more prevalent in very young children (especially infantile fibrosarcoma), are locally aggressive. Since metastases are unusual in this group of tumors, complete surgical resection is generally curative. However, these tumors often present a therapeutic challenge because of the location which makes complete surgical resection difficult. Among the malignant soft tissue tumors, rhabdomyosarcoma is most frequent. It is an aggressive high-grade tumor, with local invasiveness and a propensity to metastasize. These tumors respond to chemotherapy and radiotherapy. Neonates with rhabdomyosarcoma seem to have a worse prognosis than in older age groups. This may be a result of inappropriate dosing of chemotherapeutic agents and decreased use of radiation therapy among other factors

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.

    A. D. Fricke, author

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    Black and white photograph of author, A. D. Fricke

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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