11 research outputs found
The Human Microbiome and Cancer
No full textThis eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac
OSTVARENJE SOCIJALNE PRAVDE PROHIBICIJOM KAMATE I LIHVARSTVA-Fundamentalna intencija islamskog bankarstva i finansija
No full textCilj ovog teksta je da predstavi fundamentalnu intenciju islamskog prava u pogledu zabrane kamate, a to je prevencija eksploatacije ljudi i ostvarenje socijalne pravde. Autor iznosi da je jedna od primarnih karakteristika islamskih finansija zabrana kamate, te pravi distinkciju između beskamatnog bankarstva i bankarstva koje kamatu smatra apsolutno zabranjenom. Autor predstavlja mišljenja klasičnih i savremenih ekonomista i njihovu percepciju kamate kao i njihove teorije opravdanja kamate kao takve. S druge strane, autor naglašava da se islam, kao sveobuhvatan i inkluzivan sistem života, utemeljen na Objavi, bazira na kategoričkoj zabrani kamate s ciljem prevencije eskploatacije ljudi i ostvarenja socijalne pravde kao fundamentalne intencije šerijata
The Human Microbiome and Cancer
No full textThis eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac
POVIJESNA, SAVREMENA I FILOZOFSKO-RELIGIJSKA PERSPEKTIVA ODNOSA RELIGIJE I MORALA: KOMPLEMENTARNOST ILI KONTRADIKTORSNOST
No full textOvaj rad istražuje kompleksan odnos između religije i morala kroz historijsku, filozofsku i savremenu perspektivu. Autor prikazuje kako su moralne norme kroz historiju često bile povezane sa religijskim uvjerenjima, od drevnih civilizacija i srednjovjekovne Evrope, do promjena tokom prosvjetiteljstva. Kroz tri pristupa - religija kao osnova morala, moral bez religije (relacija kontradiktornosti) i komplementarna veza između njih - rad nudi uvid u različite naučne stavove na ovu temu. Religija se tradicionalno smatra temeljem moralnih normi, dok je Kant zasnovao etiku na razumu, a Niče kritikovao religijski moral. Rad, također, analizira kako različite religije, poput istočnih religija, judaizma, kršćanstva i islama, oblikuju moralne vrijednosti kroz svoja učenja. Naravno, uzimajući u obzir religijski background autora ovog teksta, veći fokus je stavljen na ulogu islamske percepcije morala. Takva pozicija uopće ne umanjuje naučnu vrijednost samog teksta kao takvog. Sociološke, filozofske i empirijske kritike vjerskog morala dodatno osvjetljavaju izazove sa kojima se moral suočava u modernom društvu, dok se sekularni moral, poput kantovske etike, razmatra kao alternativa. Sinergija religije i morala nesumnjivo vodi hmanizaciji čovjeka i miru. Na kraju, autor naglašava ulogu islamskog svjetonazora u transmisiji morala te važnosti multidisciplinarnosg pristupa za razumijevanje interakcije između religije i morala u savremenom svijetu
الصحفي الأديب أنتوني شديد : شهادة شخصية وإضاءة نقدية / Journalist and Writer Anthony Shadid: Personal Testimony and Critical Insights
No full text[This homage to the late journalist and writer Anthony Shadid (1968-2012) highlights his importance as a literary figure. Weaving Shadid\u27s words, his work, and the author\u27s own interactions with him, the article promotes a more profound appreciation of creative nonfiction. Narrating a final conversation with Shadid and drawing on an interview with his editor George Hodgman, the article brings out elements that elevate his two final books—House of Stone and Night Draws Near—to the status of literature. تهدف هذه الشهادة إلى الوفاء بذكرى الصحفي والكاتب الراحل أنتوﻧﻲ شديد ، عبر تسليط الضوء على أهميته بوصفه ﺃﺩﻳﺒﺎً . تناقش المقالة ضرورة وجود تقدير أعمق للونٍ أدبي لم يلق الاهتمام الذي يستحق ، وهو السرد الخبري الإبداعي creative nonfiction ، وذلك عبر نسج كلمات وكتابات أنتوﻧﻲ شديد ، ولقاءات شخصية معه ، نحو هذا المبتغى . فبين ذكرى آخر لقاء جمع الكاتب بأنتوني شديد ، ومقابلة مع محرر كتبه ، تستعرض المقالة العوامل التي أسهمت في رفع كتابيّ أنتوني شديد الأخيرين إلى مصاف الأدب .
Formation of Chromosomal Domains by Loop Extrusion
No full textSummaryTopologically associating domains (TADs) are fundamental structural and functional building blocks of human interphase chromosomes, yet the mechanisms of TAD formation remain unclear. Here, we propose that loop extrusion underlies TAD formation. In this process, cis-acting loop-extruding factors, likely cohesins, form progressively larger loops but stall at TAD boundaries due to interactions with boundary proteins, including CTCF. Using polymer simulations, we show that this model produces TADs and finer-scale features of Hi-C data. Each TAD emerges from multiple loops dynamically formed through extrusion, contrary to typical illustrations of single static loops. Loop extrusion both explains diverse experimental observations—including the preferential orientation of CTCF motifs, enrichments of architectural proteins at TAD boundaries, and boundary deletion experiments—and makes specific predictions for the depletion of CTCF versus cohesin. Finally, loop extrusion has potentially far-ranging consequences for processes such as enhancer-promoter interactions, orientation-specific chromosomal looping, and compaction of mitotic chromosomes
Any notebook served: authoring and sharing reusable interactive widgets
No full textThe open-source Jupyter project has fostered a robust ecosystem around notebook-based computing, resulting in diverse Jupyter-compatible platforms (e.g., JupyterLab, Google Colab, VS Code). Jupyter Widgets extend these environments with custom visualizations and interactive elements that communicate directly with user code and data. While this bidirectional communication makes the widget system powerful, its architecture is currently tightly coupled to platforms. As a result, widgets are complex and error-prone to author and distribute, limiting the potential of the wider widget ecosystem. Here we describe the motivation and approach behind the anywidget project, a specification and toolset for portable and reusable web-based widgets in interactive computing environments. It ensures cross-platform compatibility by using the web browser’s built-in module system to load these modules from the notebook kernel. This design simplifies widget authorship and distribution, enables rapid prototyping, and lowers the barrier to entry for newcomers. Anywidget is compatible with not just JCPs but any web-based notebook platform or authoring environment and is already adopted by other projects. Its adoption has sparked a widget renaissance, improving reusability, interoperability, and making interactive computing more accessible
Narrative threads: ethnographic tourism, Romani tourist tales, and fiber art
Get PDFThis thesis examines the need for the ethnographer to process their own emotions and experiences as part of the ethnographic experience. Specifically, it argues for the credibility of artistic expression resulting from fieldwork.
Drawing on the author’s experience during the 2012 inaugural "Romani Music, Culture, and Human Rights" study abroad program at the University of Pittsburgh, this thesis offers an analysis of five works of fiber art. Originally perceived by the author as separate from the thesis writing process, they became an integral part of thesis once they were recognized as the non-verbal processing of the my emotional response to events abroad and, therefore, essential components of the research process.
I argue that emotional processing is an integral part of writing an ethnography, for as the ethnographer works through their experiences, their understanding of the events changes, and this in turn impacts the ways in which the ethnographic is perceived and analyzed
Schooling for 'lesser beings'
No full textUsing Edward Said’s notion of ‘lesser beings’, it is argued that the political culture of schooling for Maori was and still is part of a pervasive Western European intellectual climate and culture which has a quite recent history, and which provided powerful support for the notion of Europe possessing a categorical superiority over all other continents, which in turn justified imperialism or neo-colonialism as civilising missions.
Racism and violence were endemic in colonialism and, despite the claimed moral high ground, were endemic in Aotearoa/New Zealand. War was eulogised in the Native School system more than once. The rise and demise of the World War II Maori War Organisation is illustrative of the rejection of Maori aspirations. There were still no Maori in the senior echelons of the Maori Department in 1972.
The Native, later Maori, School system was overtly designed to 'Europeanise' Maori children and therefore Maori society. Individualism was deeply embedded in English and set-tler thinking, whilst communal, ‘communist’ Maori society was to be destroyed.
The thesis examines images of colonialism, empire and imperialism in fiction and non-fiction, New Zealand and British, for adults and children, and notes the attitudes of think-ers like J S Mill and Darwin, of children’s authors Jules Verne and G H Henty, and of New Zealand author William Satchell. The images continue, pervasive and endemic, in recent adult novels. Science also played a role, as did history.
Ranginui Walker, who is Maori, is the only historian to have written a history of New Zea-land which addressed the issue of waste lands, an issue on which Pakeha historians have a blind spot. New Zealand encyclopedia do not index ‘waste land’ or ‘confiscation’. Only two Waikato histories deal adequately, or even accurately, with confiscation, the central episode in the history of the Waikato. Tourist material is equally illustrative.
The Native Schools section of the Education Department ran the Native Schools like a fiefdom, operating in legislative and regulatory black holes for the first thirty years and for much of the time after that. Teachers were moved around at will.
The practice of James H Pope, the first inspector of Native Schools, is closely and critically examined, and negatively assessed. His official writings were consistently derogatory of Maori, and his decisions in respect of Te Kopua Native School were at times detrimental to the pupils. Pope was a product of his times.
The Te Kopua record is closely scrutinised, and the practice of the Education Department is frequently found wanting. It is probable that the establishment of the school was aimed to destabilise King Country Maori, not to benefit the children. It is a story of Maori co-operation and contribution.
Part Two is a detailed partial biography of Te Kopua, it being argued that until there is a significant corpus of studies of Native Schools a valid history of the Native/Maori School system and of schooling for Maori is not possibl
Archi-texture: meditations on the mediations of dwelling
Get PDFThis thesis is an inter-disciplinary and inter- cultural exploration of home as understood as the place in which we usually live. Empirical research in an Australian suburb and an Indian town provide the fabric from which cultural studies engages with phenomenology to produce a design used to cut and style this exploration. Motivated by an interest in what threads contribute to the weave of contemporary household dwelling, this thesis revisits the two questions used by Heidegger to frame his essay 'Building Dwelling Thinking': What is it to dwell? and How does building belong to dwelling? It is an inquiry committed to its respondents as bearers and representatives of 'structures of feeling' circulating within the socio-cultural milieu or habitus in which they live and engage with the idea of 'home'. This inquiry offers an exploration of the chief constituent mediums of home which I call its 'archi-texture'. As such, it looks at location, physical and material attributes, domestic technology and household membership as framed by the presence or absence of a family. This thesis is almost certainly the only example of an empirically grounded examination of Heidegger?s ontological exposition of dwelling. Hence I position it as a meditation on the mediations of dwelling rather than a judgmental critique, although in no sense do I believe it to be either a dispassionate position nor an impartial digest of the research material
