48 research outputs found

    Temporomandibular Joint Pain is Negatively Correlated to TNF Alpha and Osteoprotegrin Content in Synovial Fluid in Patients with Juvenile Idiopathic Arthritis.

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    Objective: Temporomandibular joint (TMJ) involvement occurs in up to 80% of children with juvenile idiopathic arthritis (JIA). Little is known with regard to the complexity of the protein profile in synovial fluid (SF) from JIA arthritis during growth as compared to both JIA and rheumatoid arthritis (RA) of adults. Design: Synovial fluid was collected from 54 joints/30 patients with TMJ arthritis (JIA 35 joints/20 patients, JIA adults 9 joints/5 patients, RA 10 joints/5 patients). Three cytokines and seven bone markers were quantified using Luminex multiplex assays and compared to demographic and clinical data of function and pain. Results: Pain (spontaneous and upon palpation) and duration of pain were all negatively correlated with the TMJ SF content of tumor necrosis factor (TNF)-α. The level of Adrenocorticotropic hormone (ACTH) was negatively correlated to TMJ pain upon palpation and post-treatment pain and function. The concentration of ACTH was significantly lower in SF in JIA (1.4 ± 2.8 pg/ml) compared to adults with JIA (4.7 ± 12.2 pg/ml) and significantly higher compared to adults with RA (0.8 ± 1.5 pg/ml). Osteoprotegerin (OPG) was negatively correlated to spontaneous pain. Conclusions: Our results indicate that the local concentrations of TNF-α, ACTH and OPG in TMJ fluid may not contribute to TMJ pain and tissue destruction in JIA/RA patients. © 2014 Olsen-Bergem H, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

    Behandling med implantatforankrede protetiske erstatninger

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    Denne prosjektoppgaven omhandler behandling med implantater og implantatforankret protetikk. Implantatbehandling er en relativt ny behandlingsmåte med en voksende forskningsmasse. Oppgaven er ment som en oppsummering av kunnskap rundt dette temaet, men også å kunne egne seg som en formidling av kunnskap til pasienter/personer som har behov for implantatbehandling. Å bli behandlet med implantatforankret protetikk er en behandlingsprosedyre som tar for seg behandling innen henholdsvis fagfeltene protetikk og bittfunksjon, periodonti og oral kirurgi og oral medisin. Denne oppgaven omfatter derfor tre fagfelt og har hver sin hovedveileder: PhD og spesialistkandidat i periodonti Odd Carsten Koldsland,PhD og spesialist i protetikk og bittfunksjon Carl Hjortsjö er veileder i protetikkdelen, og PhD kandidat og spesialist i oral kirurgi og oral medisin Heming Bergem-Olsen i kirurgidelen. Professor Anne Merete Aass har hatt en overordnet koordineringsrolle. Det har lenge vært behov for en brosjyre med lettfattelig informasjon angående implantatbehandling beregnet på pasienter ved Det odontologiske fakultet. Mye av den pasientinformasjon som er tilgjengelig i dag er basert på informasjon fra implantatprodusenter. Det er ønskelig med mer nøytral informasjon støttet av vitenskapelige studier

    Self-exercise programmes and occlusal splints in the treatment of TMD-related myalgia – Evidence-based medicine?

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    Background The low‐cost and reversible treatments concerning disorders of the masticatory muscles represent a vast array of regimens. Common treatments include information, stretching exercises, manual therapy, acrylic splints and cognitive behavioural therapy. Objective The aim of this study was to evaluate the evidence behind the use of self‐exercising programmes and occlusal splints in the treatment of myofascial pain. Methods We conducted a thorough search of five databases, using four cardinal search terms in combination with twelve supporting terms. We also assessed the evidence quality, using GRADEpro software. Results The search resulted in 4967 individual studies. 18 studies met the inclusion criteria and were re‐evaluated. Conclusion The selected studies were in favour of a self‐care or an occlusal splint treatment of myalgia. However, a GRADE assessment showed that 14 of the 18 selected studies had low or very low evidence quality. Studies also showed weaknesses with regard to nomenclature and reproducibility. Hence, it is our professional opinion that the evidence level for prescribing self‐exercises and occlusal splints in the treatment of myalgia is low

    Temporomandibular pain and quality of life assessment in adolescents in a Norwegian cohort

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    Abstract Objective The objective was to examine the prevalence of pain from the face and temporomandibular joint (TMJ) and oral function in adolescents and contribute to more focus on this patient group. Methods A total of 957 adolescents were included in this study, in age cohorts 18, 16, and 14, scheduled for a dental recall examination. Clinical data were collected as a part of the routine clinical examination. All participants also answered a survey. Results Almost half of the participants had experienced facial pain in the last 3 months, headache being the most prevalent site reported. A significantly higher prevalence was found for females for all pain sites, and facial pain was significantly higher among the oldest. A reduced maximal incisal opening was significantly associated with higher reported facial/jaw pain, with increased mouth opening pain and chewing pain. Fifty‐seven percent of the participants reported the use of nonprescription painkillers, highest among females, and in the oldest age cohort, mainly caused by nonfeverish headaches. General health was found to be negatively correlated to facial pain, headache, pain intensity, and duration, pain upon oral function, and oral movement, as well as the use of nonprescriptive drugs. Females in the older age group, experience less quality of life in general, as they felt more worried, anxious, lonely, and sad, compared to males. Conclusion Facial‐ and TMJ pain was higher in females, and higher with increasing age. Almost half of the participants had experienced facial pain in the last 3 months, headache being the most prevalent site reported. General health was found to be negatively correlated to facial pain

    Example of content analysis.

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    BackgroundMore than 70% of respondents in a previous survey among paramedics reported use of coercion or physical force towards patients. Coercion outside hospital is not permitted, and neither routines nor equipment intended for physical restraint is available in the Norwegian ambulance services. Paramedics carry out assignments involving use of force and coercion on unclear legal grounds, with no training in techniques or proper equipment. Attitudes and experiences of healthcare workers regarding incidents involving coercion in mental health care services are frequently reported in the research literature, yet little is known about paramedics’ experiences, and which factors contribute to their moral stress.MethodsIn the period June-August 2021, almost 400 employees in the ambulance services in a county in the eastern part of Norway were invited to answer a digital questionnaire. One question had an open text field with the question "Can you say something about how you experience transporting patients where force has to be used to secure the patient during transport?". The answers were analyzed using Graneheim and Lundman’s content analysis.ResultsWe received eighty-five completed responses (response rate 21%). Force was used by 62 paramedics. Twenty-three left the text field open. The answers showed many unique responses. Content analysis resulted in two overarching themes; 1) lack of routines, equipment, and training regarding use of coercion and force in the ambulance service, and 2) paramedics were confronted with ethical dilemmas, alone and without support from legislation or management.ConclusionsThe paramedics experienced discomfort related to the exercise of force and coercion during ambulance assignments due to the experience of unclear legislation, lack of training, routines, and equipment in addition to frequent ethical dilemmas and the concern about lack of support from the employer. A clearer legal basis, adapted equipment in the ambulance and regular training, will contribute to greater security in the performance of the work, which will provide safer and more caring treatment for the patients and less moral stress for the staff. With established routines, the employer will be implicitly obliged, and paramedics will be safer in the performance of their work. Ethical reflection must be offered and put into a system.</div

    "Some missions can be quite emotionally painful." Paramedic´s experience exercising coercion during assignments—A qualitative study

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    Background More than 70% of respondents in a previous survey among paramedics reported use of coercion or physical force towards patients. Coercion outside hospital is not permitted, and neither routines nor equipment intended for physical restraint is available in the Norwegian ambulance services. Paramedics carry out assignments involving use of force and coercion on unclear legal grounds, with no training in techniques or proper equipment. Attitudes and experiences of healthcare workers regarding incidents involving coercion in mental health care services are frequently reported in the research literature, yet little is known about para- medics’ experiences, and which factors contribute to their moral stress. Methods In the period June-August 2021, almost 400 employees in the ambulance services in a county in the eastern part of Norway were invited to answer a digital questionnaire. One question had an open text field with the question "Can you say something about how you experience transporting patients where force has to be used to secure the patient during transport?". The answers were analyzed using Graneheim and Lundman’s content analysis. Results We received eighty-five completed responses (response rate 21%). Force was used by 62 paramedics. Twenty-three left the text field open. The answers showed many unique responses. Content analysis resulted in two overarching themes; 1) lack of routines, equip- ment, and training regarding use of coercion and force in the ambulance service, and 2) paramedics were confronted with ethical dilemmas, alone and without support from legisla- tion or management. Conclusions The paramedics experienced discomfort related to the exercise of force and coercion during ambulance assignments due to the experience of unclear legislation, lack of training, rou- tines, and equipment in addition to frequent ethical dilemmas and the concern about lack of support from the employer. A clearer legal basis, adapted equipment in the ambulance and regular training, will contribute to greater security in the performance of the work, which will provide safer and more caring treatment for the patients and less moral stress for the staff. With established routines, the employer will be implicitly obliged, and paramedics will be safer in the performance of their work. Ethical reflection must be offered and put into a system.acceptedVersio

    Development of a mooring system based on polyester and nylon

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    For å nå målene som nesten alle verdens land har blitt enige om gjennom Parisavtalen, må jobben intensiveres rundt fornybare energikilder. Vindkraft har pekt seg ut som en av de ledende alternativene til fossilt brensel og flytende offshore vindkraft gir mulighet for å nå store uberørte vindresurser som ikke var mulig tidligere. Denne oppgaven tar for seg oppgaven å utvikle et forankringssystem basert på polyester og nylon. Da materialene er relativt billige kan dette redusere kostnadene og gjøre flytende vindkraft mer konkurransedyktig. Den halvt-nedsenkbare-plattformen OO Star, utviklet av Dr. Techn. Olav Olsen, er valgt til evalueringen på 100 meters dyp for et bruddgrensetilfelle (ULS) og en utmattingstilstand (FLS).To reach the goals that almost every country has agreed on through the Paris agreement, must the development of renewable energy sources be intensified. Wind power has become one of the most competitive energy sources to fossil fuels and floating offshore wind power makes it possible to harvest vast unused resources previously not obtainable. This thesis addresses the task of developing a mooring system based up on polyester and nylon. As the materials are relatively cheap, this can reduce costs and make floating wind power more competitive. The semi-submersible platform OO Star, delevoped by Dr. Techn. Olav Olsen, has been chosen for evaluation on the depth of 100m. These evaluations contain ULS and FLS.M-MP
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