170 research outputs found

    Evidence for a role of nitric oxide in iron homeostasis in plants

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    Nitric oxide (NO), once regarded as a poisonous air pollutant, is now understood as a regulatory molecule essential for several biological functions in plants. In this review, we summarize NO generation in different plant organs and cellular compartments, and also discuss the role of NO in iron (Fe) homeostasis, particularly in Fe-deficient plants. Fe is one of the most limiting essential nutrient elements for plants. Plants often exhibit Fe deficiency symptoms despite sufficient tissue Fe concentrations. NO appears to not only up-regulate Fe uptake mechanisms but also makes Fe more bioavailable for metabolic functions. NO forms complexes with Fe, which can then be delivered into target cells/tissues. NO generated in plants can alleviate oxidative stress by regulating antioxidant defense processes, probably by improving functional Fe status and by inducing post-translational modifications in the enzymes/proteins involved in antioxidant defense responses. It is hypothesized that NO acts in cooperation with transcription factors such as bHLHs, FIT, and IRO to regulate the expression of enzymes and proteins essential for Fe homeostasis. However, further investigations are needed to disentangle the interaction of NO with intracellular target molecules that leads to enhanced internal Fe availability in plants.RKT is grateful to Department of Science and Technology-Science and Engineering Research Board (DST-SERB) New Delhi, for a Teachers Associateship for Research Excellence (TAR/2019/000064).Tewari, RK (corresponding author), Univ Lucknow, Dept Bot, Lucknow 226007, Uttar Pradesh, India. [email protected]

    Assessment of Articular Cartilage by Second Harmonic Microscopy: Challenges and Opportunities

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    Second harmonic microscopy (SHM) has emerged as a powerful non-destructive optical imaging modality that has high potential to perform the advanced structural characterization of intact articular cartilage. This article provides the current status, opportunities, and challenges of SHM for the use in cartilage evaluation. A novel perspective on SHM is being addressed that includes the reason, need and the importance of SHM in the assessment of articular cartilage. By taking the advantage of collagen specificity and high-resolution imaging, SHM can detect the structural and morphological changes in early stage cartilage damage that would otherwise be overlooked by standard clinical imaging methods such as radiography and arthroscopy. The current status of SHM for articular cartilage analysis and the major progress reported in recent literature are briefly described herein. We summarize the status of scientific efforts and the challenges that need to overcome before moving toward clinical applications of SHM in the context of cartilage evaluation.publishedVersionCopyright © 2019 Kumar and Kumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms

    Collected Papers (Papers of Mathematics or Applied Mathematics), Volume V

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    This volum includes 37 papers of mathematics or applied mathematics written by the author alone or in collaboration with the following co-authors: Cătălin Barbu, Mihály Bencze, Octavian Cira, Marian Niţu, Ion Pătraşcu, Mircea E. Şelariu, Rajan Alex, Xingsen Li, Tudor Păroiu, Luige Vlădăreanu, Victor Vlădăreanu, Ştefan Vlăduţescu, Yingjie Tian, Mohd Anasri, Lucian Căpitanu, Valeri Kroumov, Kimihiro Okuyama, Gabriela Tonţ, A. A. Adewara, Manoj K. Chaudhary, Mukesh Kumar, Sachin Malik, Alka Mittal, Neetish Sharma, Rakesh K. Shukla, Ashish K. Singh, Jayant Singh, Rajesh Singh, V.V. Singh, Hansraj Yadav, Amit Bhaghel, Dipti Chauhan, V. Christianto, Priti Singh, and Dmitri Rabounski

    Open Access to public funded research: a discussion in the context of Mahatma Gandhi University digital archives of doctoral dissertations

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    The importance of doctoral dissertations, the extent of public funds utilized for their production, their need for open access, concepts of Open Access (OA), and the arguments for and against OA are discussed in detail. A brief historical outline of the attempts in India for digitizing and providing OA to dissertations is provided. The development of the Mahatma Gandhi University (MGU) Open Access Digital Archive is examined as an opportunity for other implementers and developers to gain both technical and non-technical insight. The paper suggests establishment of a national agency for ensuring OA to doctoral dissertations produced in Indian universities. Discussion on OA initiatives and the creation of OA Archive of dissertations at MGU can reveal to other institutions in India that it is not a costly or difficult task as generally considered. The paper can infuse interest and confidence to universities and research institutions in India to provide OA to their research works
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