1,724,189 research outputs found
Vitiligo management: Combination of surgical treatment and phototherapy under reflectance confocal microscopy monitoring
OBJECTIVE: Vitiligo is a chronic acquired pigmentary skin disorder characterized by well-defined asymptomatic white macule as a result of loss of functional melanocytes in the epidermis. The psychological burden experienced by patients is of great interest and consequently research of the best medical approach is constantly developing. This review focuses on surgical approach and the combination of surgery and phototherapy. In addition, reflectance confocal microscopy (RCM) could be useful to discriminate between stable or active vitiligo and to evaluate efficacy of therapy. MATERIALS AND METHODS: We searched PubMed with the following keywords: (vitiligo[ Title/Abstract]) AND therapy[Title/Abstract]) AND surgery[Title/Abstract]) AND phototherapy[ Title/Abstract]) AND reflectance confocal microscopy[ Title/Abstract]). RESULTS: To date, surgery is an effective therapeutic approach in stable vitiligo. Phototherapy, which is the most effective medical option, can improve the results obtained with surgery if performed in combination. Preliminary data show that RCM help physician in evaluating stability of vitiligo and is also useful to monitor clinical response. CONCLUSIONS: Vitiligo is a psychosocially debilitating disease requiring a multidisciplinary approach. Even if a standard management could not be stated, combination of surgery and phototherapy in stable vitiligo could lead to great improvement than monotherapy. RCM is a modern tool which should be used in order to perform surgery and phototherapy properly and to subsequently evaluate efficacy on a microscopic level
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Fertirrigazione organo-minerale in Campania. Gli effetti sulla PLV di lattuga e melanzana
Upgrade of Exciter for Synchronous Generators basing on the Hybrid Excitation Concept
In the classical brushless arrangement, the field current of wound-field synchronous generators (SGs) is provided by exciters through rotating diode rectifiers. The control of the SG field current is achieved indirectly by regulating the field current of the exciter, whose excitation winding is stationary. This paper investigates the possibility to equip the exciter with hybrid excitation by adding surface-mounted permanent magnets (PMs). While a hybrid PM-field winding exciter has already been proposed in a recent work, where the selected condition was the rated no-load operation of the SG, in this paper the PMs are designed to sustain the generating set (genset) operation at a suitably selected load condition. This permits to further reduce the excitation losses of the exciter and to operate the genset even in case of full failure in the exciter field system, including the related electronic controller
An Innovative Electric Motor Topology Developed for 2- and 3-Wheelers
This paper presents a comparative study between the state-of-the-art electrical machine topologies and an alternative innovative rare-earth-free solution. Focus is placed on the electric 2- and 3-wheelers. This application requires electrical machines typically in the range of 4 kW to 10 kW, to be manufactured and designed for cost-effective small to mid-size vehicles. The comparison is made taking into account major 2- and 3-wheelers attributes of efficiency, cost, sustainability, weight and performance. The different electrical machine topologies discussed in this paper are interior permanent magnet machines, axial flux permanent magnet machines, and axial flux electrically excited synchronous machines. This study is carried out on a 5.5 kW electrical machine. However, this paper results and conclusion may be extended also to other power levels in this segment. Besides the comparison in attributes, production aspects are also taken into account in this study. Focus in this research is put on central-drive propulsion architecture which covers majority of 2- and 3-wheelers market today. In-wheel configuration will be addressed in future publications
The impact of a preopening session on subsequent trading: An experimental analysis
In this study, we examine the influence of a preopening call market (CM) session on the subsequent continuous double auction (CDA) trading phase within a combined market structure (CMDA). We propose that the introduction of a CM phase before the CDA could potentially mitigate price volatility during the CDA by facilitating the disclosure of agents' private information through the preopening pricing phase. Our findings reveal a positive relationship between the preopening price and the prices traded during the subsequent phase, alongside a decreased deviation of prices from their fundamental value when high-quality information is available. These results suggest that a well-defined preopening phase has the potential to improve market efficiency
“Less is more” or “more is better”? The effect of asymmetric information distribution on market efficiency and wealth inequality
We provide experimental and empirical evidence on the role of information distribution and accuracy in solving market inefficiency and the related welfare implications. To this end, we vary both (i) the informativeness of the private signal released and (ii) the fraction of informed traders. At market level, results evidence how higher informativeness is not conclusive, since mispricing persists. Furthermore, a reduction of signal precision reflects traders' uncertainty aversion through lower price volatility. Results are robust when both all and half of the players are informed (i.e., received the signals). At subject level, we observe that informed traders are gaining more profits. Anyway, the signal precision and distribution do not statistically change the profits of both net market-winners and net market-losers. This suggests that-on average-the intensity of asymmetric information distribution (i.e., the size of the information imbalance between informed and uniformed traders) does not alter the wealth distribution
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