67 research outputs found

    La cura dei folli nel Progetto di Stabilimento per alienati proposto da Biagio Gioacchino Miraglia

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    The essay is a study of the evolution of the mental institutions legislation after the Italy Unification. The author highlights the problems that Italy had to face regarding the adjustment of institutional arrangements in the healthcare, which urgently needed legislation to make uniform the mental institutions management and organization. Alienists were pressing for a primary and active role in the debate on the mental institutions legislation. Among these was certainly Biagio Gioacchino Miraglia who proposed in South Italy an important project

    Session H/11.8 -Effect of management and housing on horse welfare Corresponding author: [email protected] Three-dimensional design of a horse stud like better toll for technical choices of housing and welfare

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    Abstract It is well known that captivity and the following upsetting of the horse natural habits and physiological activities have made the horse defenceless towards the numerous dangers and have exposed it to a wide range of risks. As a consequence, the safety of the infrastructures where the athlete spends the majority of its life time represent a fundamental aspect strictly linked to the prevention modalities of many pathologies found within equestrian veterinary practice. In recent year the three-dimensional designs are more and more utilised to have a complete vision of the structures. In the case of horse studs, the three-dimensional design represents the best solution to verify, in virtual imagines, the technical choices not only for housing bur also for improving welfare conditions. In fact it is possible to hypothesize and to virtually test the operative conditions needed both in terms of structures and welfare. The results of this kind of representation is optimal to research the best welfare conditions. This study refers to a virtual three-dimensional design of an equestrian centre destined to show jumping horses. This facility includes the realization of different structures such as stud and wasting areas, covered grounds, open air fields, open fields, rings, club services, competition arenas with tribunes, jury, services for public, etc.

    A proposito di formante giurisprudenziale e principio di legalità in ambito privatistico

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    Abstract – Italiano L’articolo affronta il tema del crescente protagonismo del formante giurisprudenziale nel diritto privato italiano e delle sue implicazioni sul principio di legalità. Attraverso l’analisi critica di tre casi emblematici (caparra confirmatoria, stepchild adoption, abuso del diritto), l’Autore evidenzia come l’espansione dell’interpretazione giudiziaria, fondata sull'applicazione diretta dei principi costituzionali, senza il medio della legge ordinaria (Drittwirkung) , rischi di compromettere la certezza del diritto e il ruolo della legge come fondamento dell’ordinamento privatistico. Il saggio richiama l’attenzione sulla tensione tra creatività giudiziale e certezza del diritto, proponendo una riflessione sulla necessità di ristabilire l’equilibrio tra i poteri in cui si articola lo Stato di diritto, e di riaffermare, nei sistemi di civil law, la necessaria e strutturale funzione servente della giurisdizione e dell'avvocatura rispetto alla Legge. Abstract - Inglese The article addresses the growing prominence of case law in Italian private law and its implications for the principle of legality. Through the critical analysis of three emblematic cases (caparra confirmatoria, stepchild adoption, and abuse of rights), the Author highlights how the expansion of judicial interpretation—based on the direct application of constitutional principles without the mediation of statutory law (Drittwirkung)—risks undermining legal certainty and the role of legislation as the foundation of the private law system. The essay draws attention to the tension between judicial creativity and legislative constraint, offering a reflection on the need to re-establish a proper balance among the powers that constitute the rule of law, and to reaffirm the subordinate role of both the judiciary and the legal profession in relation to the law, within civil law systems

    Defining a functional network homeostasis after stroke: EEG-based approach is complementary to functional MRI

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    We have read with great interest the article by Adhikari et al . entitled ‘Decreased integration and information capacity in stroke measured by whole brain models of resting state activity’ recently published in Brain (Adhikari et al. , 2017). The authors of this excellent article found that the brain network functional connectivity, evaluated by functional MRI, is impaired among subjects with subacute stroke, being the graph theoretical measures of integration and segregation decreased. This kind of network reorganization occurs both in the whole cerebral network and in the seven resting state subnetworks [dorsal attention network (DAN), ventral attention network (VAN), motor network, visual network, frontal parietal network (FPN), language network (LAN) and default mode network (DMN)]. In particular, the integration is decreased among all resting state net- works, while the segregation, intended as mean information capacity, is decreased globally and among DAN and FPN resting state networks. In this frame, we would like to convey an analogous and complementary EEG-based approach that could add more ‘dynamic’ information about functional cortical connectivity, being EEG signals directly related to the cyclic firing of the neuronal assemblies, reaching thus a temporal discrimin- ation—particularly when fast EEG rhythms are con- sidered—of few tens of milliseconds. Requiring a balance in the brain activity between local specialization and global integration (Tononi et al ., 1994), properly quantified by a small-world network model (Watts and Strogatz, 1998), characterized by high clustering coefficient (index of functional segregation) and short path length coefficient (index of functional integration) (Bassett and Bullmore, 2006; Stam and Reijneveld, 2007), we evaluated via EEG the small-world characteristics (small-worldness) of resting state cortical networks in 30 consecutive patients with acute ischaemic stroke (Caliandro et al. , 2017). In fact, using the eLORETA software (Pascual-Marqui, 2002), it is possible to reconstruct 42 regions of interest, corresponding to 42 Brodmann areas, for each hemisphere, and to calculate the current density time series of the regions of interest (lagged linear coherence) (Pascual-Marqui, 2007; Pascual- Marqui et al ., 2011) between all possible pairs of the regions of interest for each of the seven independent EEG frequency bands of delta (2–4Hz), theta (4–8Hz), alpha 1 (8–10.5Hz), alpha 2 (10.5–13Hz), beta 1 (13–20Hz), beta 2 (20–30Hz), and gamma (30–45Hz) rhythms for each subject. Given this, an EEG-derived cortical network in which the nodes are represented by the Brodmann areas and the edges are weighted by lagged linear connectivity values can be reconstructed (Pascual-Marqui, 2007). The aforementioned EEG- and graph theory-based approach allowed us to find network rearrangement in a frequency-dependent modality doi:10.1093/brain/awx271 BRAIN 2017: 140; 1–2 | e71 Advance Access publication November 3, 2017 ß The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: [email protected] Downloaded from https://academic.oup.com/brain/article-abstract/140/12/e71/4590109 by universitï¿1⁄2 cattolica del sacro cuore user on 20 February 2018 (Caliandro et al. , 2017). In particular, in the delta band we found a decreased small-worldness (similar to the rearrangement in delta band, we found a bilateral theta band small-worldness reduction only in patients with left hemispheric stroke). On the hand, we found an increased small-worldness in alpha 2 band. It is noteworthy that the abovementioned network changes were found in the hemi- sphere ipsilateral to the ischaemic lesion, in the contralateral hemisphere and in the whole brain. Compared with the Adhakiri et al . study, our data show a greater complexity of cortical resting state remodelling after acute stroke, probably because EEG signals reflect the intricacy of neuronal spontaneous time-varying oscilla- tions. It is noteworthy that segregation and integration are simultaneously increased and reduced when compared to healthy subjects according to the analysed EEG frequency. Indeed, segregation is increased in low frequencies (delta and theta) and reduced in alpha 2 frequency. A specular behaviour is observed when evaluating integration, where a reduction in delta and theta and an increase in alpha 2 are observed. In other words, we facilitate a multi- modal dynamic change, which could be interpreted as an attempt to reach a balance between the damage caused by the lesion and the brain compensatory reaction. We can hypothesize that this fascinating connectivity ‘homeostasis’ has a double effect: on one hand, it confines the functional coupling among Brodmann areas ‘patho- logically’ clustered in low frequency network by reducing their global integration; and on the other, it counterbal- ances the impairment of ‘healthy’ alpha 2 clusters by strengthening the physiological alpha 2 global integration

    Inflammation and Pancreatic Ductal Adenocarcinoma: A Potential Scenario for Novel Drug Targets

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    No abstract available.Image: Mechanism of NF-κB action (Author: Boghog2 from Wikimedia Commons

    Relativistic effects on stopping power of plasmas with heavy ions

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    This work investigates the electronic stopping power for protons of a tungsten plasma at various electron densities and temperatures. The study employs a dielectric formalism to model the stopping power due to free and bound electrons, considering relativistic and non-relativistic effects. The bound electron stopping power is modeled using the shellwise local plasma approximation (SLPA) introduced by Montanari and Miraglia. The ionization state of the plasma is also examined, revealing its impact on the bound electron contribution. We compare our results with the T-Matrix approach and the Li-Petrasso model for free electrons in combination with SLPA calculations for the bound electron ones. Results demonstrate the significance of bound electron stopping power, particularly for plasma with high-Z ions. This investigation contributes valuable insights into plasma physics and fusion energy research, providing essential data for future experiments and simulations.Fil: Mendez, Marta Patricia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Chacón Gijón, Javier. Universidad de Castilla-La Mancha; EspañaFil: Vázquez Moyano, J.. Universidad de Castilla-La Mancha; EspañaFil: Barriga Carrasco, Manuel D.. Universidad de Castilla-La Mancha; Españ

    Software-defined testbed for next generation navigation transponders

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    This paper presents a software-defined testbed to perform hardware-in-The-loop test of miniaturized coherent transponders. Such a setup has been designed to minimize the access threshold for future users, heavily relying on available open source applications and commercial hardware, targeting future coherent transponders for interplanetary CubeSats. The paper presents the overall architecture of the testbed, a tradeoff to select the most suited development framework and the detailed design of the different blocks. Upcoming interplanetary CubeSat missions that would require a coherent transponder are also presented to highlight the need sof such a system. Software qualification, given the use of third-party software with multiple developers, was also addressed to guarantee performances can be consistent and reliable.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Space Systems EgineeringElectronicsAstrodynamics & Space Mission

    Negoziazione tra convenienti: rapporti patrimoniali

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    2018 - 2019The current work analyses the impact of Law No 76 of 20 May 2016 on the delimitation of the private autonomy of non-marital partners in the regulation of reciprocal property relations. The study consists of a comparison of the previous exegetical-legislative framework prior to the Novella and the following.It shows how the negotiationbetween partners was the main instrument for protecting their economic claims: first of all, it supplant a legal vacuum, whereas today, in the form of the cohabitation agreement, is the ad hoc instrument chosen by the legislature. Before the Novella, theeconomicmenage of the family of fact was implemented by means of the execution of isolated services between the partners, and the conclusion of specific contracts, both highly common and widely accepted, which were, however, strongly discussed at the point of qualification and discipline. The 2016 Law was awaited with a view of resolving these doubts definitively, but the investigation revealed that it was inappropriate. The Novella has none of the aforementioned isolated services and, although the cohabitation agreement is complete, regulates it in an ambiguous, imprecise and incomplete fashion, in particular in relation to the most problematic profile, which is the eligibility of clauses governing the effects of the voluntary dissolution of the relationship. The issue was strongly debated in the past. On the one hand, it was pointed out that this rule was the paradigmatic nature of the contract between life partners, since the crisis in the report is the elective location of the conflict between partners. On the other hand, the admissibility of these clauses was actively paid, by how many of them classified as illicit atypical agreements with non-material effects, suitable for the cover-up of personal obligations, by the indirect conditioning of the choice of the partners to continue or abort the relationship. The study therefore focuses on the impact of the codification of the cohabitation agreement on this particular debate, since in the case of the voluntary discontinuation of the relationship, the Novella reconciles the appearance of a mere maintenance obligation rather than the maintaining. We note that, owing to the ambiguity and incompleteness of the law, the interpretation of the law, the wording of which — paragraphs 50, 53 and 56 — remains open to the inclusion of the terms at issue in the cohabitation agreement. the legal literature, it is stated that there are alternative means of obtaining the aforementioned fine in an atypical contract or in a cartel after the termination of the report. However, the research shows that, as regards the former, the doubts of the past on the lawfulness of the agreement would arise, whereas in relation to the latter, the uncertainty at the point of qualification and discipline would arise. ... [edited by Author]XXXII cicl
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