1,648 research outputs found

    T.C. Powers, '25, author of the book, "Leakage: The Bleeding of the American Economy"

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    Includes letters from the American Society for Testing Material about T.C. PowersBlack and WhitePeople: Powers, T.C

    Preparation and toolkit learning

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    A product set of pure strategies is a prep set ("prep" is short for "preparation") if it contains at least one best reply to any consistent belief that a player may have about the strategic behavior of his opponents. Minimal prep sets are shown to exists in a class of strategic games satisfying minor topological conditions. The concept of minimal prep sets is compared with (pure and mixed) Nash equilibria, minimal curb sets, and rationalizability. Additional dynamic motivation for the concept is provided by a model of adaptive play that is shown to settle down in minimal prep sets.noncooperative games; inertia; status quo bias; adaptive play; procedural rationality

    Is Unlevered Firm Volatility Asymmetric?

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    Asymmetric volatility refers to the stylized fact that stock volatility is negatively correlated to stock returns. Traditionally, this phenomenon has been explained by the financial leverage effect. This explanation has recently been challenged in favor of a risk premium based explanation. We develop a new, unlevering approach to document how well financial leverage, rather than size, beta, book-to-market, or operating leverage, explains volatility asymmetry on a firm-by-firm basis. Our results reveal that, at the firm level, financial leverage explains much of the volatility asymmetry. This result is robust to different unlevering methodologies, samples, and measurement intervals. However, we find that financial leverage does not explain index-level volatility asymmetry, which is consistent with theoretical results in Aydemir, Gallmeyer and Hollifield (2006).Volatility asymmetry, Financial leverage, Financial Economics, Research Methods/ Statistical Methods, G12,

    Controversies in the management of acute tonsillitis: an evidence-based review

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    BACKGROUND: Patients admitted with acute tonsillitis generate a substantial workload for the National Health Service (NHS), placing huge financial pressures on an already overstretched budget.OBJECTIVE OF REVIEW: Due to the difficulty of accurate diagnosis and varying practices across the UK, there exist a number of controversial areas and non-standardised practice. These will be highlighted and tackled within this article.TYPE OF REVIEW AND SEARCH STRATEGY: A literature review, last performed in September 2013, searched PubMed citing variations on the areas of controversies with 'tonsillitis', 'pharyngitis' and 'pharyngotonsillitis' - from 1956 to present with language restrictions. Excluded articles included those regarding sore throat after tonsillectomy and peritonsillar abscess.EVALUATION METHOD: Titles and abstracts were initially screened, and full text of potentially relevant articles obtained. The bibliographies of articles were searched for relevant references. The references were then compiled and reviewed independently by two authors (JB &amp; TB), overseen by the senior author (EK).RESULTS: (i) Diagnosis and investigation: Use of the Centor criteria is inadequate within the secondary care setting. Blood testing is unnecessary in the majority of cases where patients do not require admission, as they are unlikely to change management. (ii) Antibiotics: Antibiotics are likely to be indicated in all those presenting to secondary ENT care, with penicillin being the antibiotic of choice for first-line therapy. (iii) Corticosteroids: Moderate evidence supports the benefit of steroid administration in this patient cohort, advocating a single dose initially followed by reassessment. (iv) Analgesia: Paracetamol and NSAIDs have good evidence of action. Codeine should be used with caution in the paediatric population. (v) Reduced admission rates and early discharge: There is evidence suggesting that a trial of medical therapy prior to admission is beneficial in reducing rates of admission and length of stay.CONCLUSIONS: Management of acute tonsillitis within a secondary care setting largely consists of anecdotal or relatively low-quality evidence. Thus, much evidence from management comes from expert opinion or practice within a primary care setting. Management across the UK can also vary greatly. An evidence-based review of best practice has been presented here, but further evidence will be required in the future examining the significance of corticosteroids and antibiotic administration in this patient cohort specifically, ensuring practice is evidence based and clinically relevant.</p

    Codiameters of 3-domination critical graphs with toughness more than one

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    AbstractA graph G is 3-domination-critical (3-critical, for short), if its domination number γ is 3 and the addition of any edge decreases γ by 1. In this paper, we show that every 3-critical graph with independence number 4 and minimum degree 3 is Hamilton-connected. Combining the result with those in [Y.J. Chen, F. Tian, B. Wei, Hamilton-connectivity of 3-domination critical graphs with α≤δ, Discrete Mathematics 271 (2003) 1–12; Y.J. Chen, F. Tian, Y.Q. Zhang, Hamilton-connectivity of 3-domination critical graphs with α=δ+2, European Journal of Combinatorics 23 (2002) 777–784; Y.J. Chen, T.C.E. Cheng, C.T. Ng, Hamilton-connectivity of 3-domination critical graphs with α=δ+1≥5, Discrete Mathematics 308 (2008) (in press)], we solve the following conjecture: a connected 3-critical graph G is Hamilton-connected if and only if τ(G)>1, where τ(G) is the toughness of G

    (13(3):51-56)酸桔葉片殊形潰瘍病斑之利用

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    Citrus canker caused by Xanthomonas citri (Hasse) Dowson is normally charac-terized by corky, hard, and somewhat suberized lesions surrounded by a yellowish halo on the infected leaves of susceptible varieties. If the canker lesion has developed quickly under extremely favorable conditions, the white spongy tissue will excruded in some degree, and accumulated on the lesions. This special canker lesions with spongy eruption of tissue will be found, sometime, when artificial inoculation was made by overstaying the inoculated plant in pot (Fig. 4) in the inoculation chamber for three or four days after inoculation. It is also easy to induce special lesions by keeping the leaves of susceptible varieties in such a semi-vivo condition as in the moistened Petri-dish (Fig. 3) placed in the incubator for five or six days after inoculation. The present author was deeply interested in the formation of this special lesion and had made his attempt to utilize them for several purposes, such as screen test for canker-control bactericides, identrfication of newly isolated canker organism, and determination of resistance of citrus varieties to the disease. The present report was made in deal with utilization of this inoculation technique for testing inhibiting effectiveness of the bactericides on the fomation of canker lesion. 柑桔類潰瘍病於極度適宜之環境下所發生之病斑,因罹病組識之海棉細胞受病原菌之刺激致呈畸形膨大,多量溢出,而形成白色隆起之明顯殊形病斑,此種殊形病斑頗易由人工接種而顯現。將酸桔半成熟葉片採下,以自來水沖洗後以解剖針輕刺一定數目之傷痍,浸漬於病原菌懸浮液,使葉面餘液陰乾後排放於潮濕培養皿之玻璃支架上,置28℃定溫箱培養六天,即可於傷痍部位呈現明顯之殊形潰瘍病斑。 筆者以此病斑形成之明顯與容易,乃探測其利用價值。本試驗以五種抗生製劑供作傷痍葉片人工接種後作藥劑侵漬處理,以葉片病斑發生數目,測定供試藥劑對病原菌之抑制或殺減效力。據試驗結果,病斑之發生與藥劑濃度具有規律之相關關係。筆者認為此法於藥劑試驗之初步選定上,為一簡便而可行之方法

    Smart Redundancy Schemes for ANNs against Fault Attacks

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    Artificial neural networks (ANNs) are used to accomplish a variety of tasks, including safety critical ones. Hence, it is important to protect them against faults that can influence decisions during operation. In this paper, we propose smart and low-cost redundancy schemes that protect the most vulnerable ANN parts against fault attacks. Experimental results show that the two proposed smart schemes perform similarly to dual modular redundancy (DMR) at a much lower cost, generally improve on the state of the art, and reach protection levels in the range of 93% to 99%.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Computer EngineeringQuantum & Computer Engineerin

    REJENERATİF VE NONREJENERATİF ANEMİLİ KÖPEKLERDE SERUM HEPSİDİN KONSANTRASYONUNUN DEĞERLENDİRİLMESİ

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    ÖZET REJENERATİF VE NONREJENERATİF ANEMİLİ KÖPEKLERDE SERUM HEPSİDİN KONSANTRASYONUNUN DEĞERLENDİRİLMESİ Kocaman B. Aydın Adnan Menderes ÜnDversDtesD, Sağlık BDlDmlerD EnstDtüsü, VeterDner FakültesD, Yüksek LDsans TezD, Aydın, 2024. Amaç: Hepsidin, demir metabolizmasının düzenlenmesindeki temel hormondur. Bu çalışmada anemili köpeklerde serum hepsidin konsantrasyonun durumunun belirlenmesi, rejeneratif ve nonrejeneratif anemili köpeklerde bu hormonun serum konsantrasyonunun karşılaştırılması ve retikülosit sayısı ve aneminin şiddeti ile serum hepsidin konsantrasyonu arasındaki ilişkilerin ortaya konulması amaçlandı. Gereç ve Yöntem: Çalışmada, Aydın Adnan Menderes Üniversitesi Veteriner Fakültesi Hayvan Hastanesi’ne getirilen 20 sağlıklı (kontrol) ve verileri dikkate alınan 47 anemili toplam 67 köpek değerlendirildi. Klinik muayenede anemi ile ilişkili bulgular gösteren hastaların hemogram sonuçlarından aneminin varlık ve şiddeti; absolut retikülosit sayısı değerlendirilerek aneminin tipi (rejeneratif ve nonrejeneratif) belirlendi. Serum hepsidin konsantrasyonu tür spesifik ELISA kiti ile ölçüldü. Belirtilen parametrelerin ölçümü bir kez yapıldı. Gruplar arası karşılaştırmalar ve korelasyonlar, uygun parametrik ve nonparametrik testlerle gerçekleştirildi. Bulgular: Rejeneratif anemi grubunun ortalama HCT değeri (%23,4) nonrejeneratif anemi grubu köpeklerin değerinden (%27,7) düşük, ortalama absolut retikülosit sayısı ise yüksek bulundu (i35,2 xi03 /µL vs. 49,9 xi03 /µL). Sağlıklı (7i,00 ng/mL) ile anemik (70,70 ng/mL) ve rejeneratif (68,82 ng/mL) ile nonrejeneratif anemili (7i,60 ng/mL) köpeklerin ortanca serum hepsidin konsantrasyonları arasındaki farklar istatistiksel anlamlı değildi. Rejeneratif anemili köpeklerde serum hepsidin konsantrasyonu ve absolut retikülosit sayısı arasında pozitif zayıf korelasyon (r=0,48) olduğu belirlendi. Sonuç: Köpeklerde serum hepsidin konsantrasyonun aneminin tipi ve şiddetine göre anlamlı farklılıklar göstermediği, rejeneratif anemide serum hepsidin konsantrasyonu ve absolut retikülosit sayısı arasında pozitif zayıf korelasyon dışındaki korelasyonların göz ardı xii edilebilecek düzeyde olduğu belirlendi. Köpeklerde serum hepsidin konsantrasyonun aneminin tipi ve şiddetine göre durumunun, serumda akut faz proteinler ve proinflamatuar sitokin konsantrasyonları altında değerlendirilmesinin yararlı olacağı kanısına varıldı.İÇİNDEKİLER KABUL VE ONAY.....................................................................................................................i TEŞEKKÜR ...............................................................................................................................ii İÇİNDEKİLER..........................................................................................................................iii SİMGELER VE KISALTMALAR DİZİNİ...............................................................................v ŞEKİLLER DİZİNİ.................................................................................................................viii RESİMLER DİZİNİ ..................................................................................................................ix TABLOLAR DİZİNİ..................................................................................................................x ÖZET.........................................................................................................................................xi ABSTRACT ............................................................................................................................xiii 1. GİRİŞ......................................................................................................................................1 2. GENEL BİLGİLER................................................................................................................2 2.i. Aneminin Tanımı.................................................................................................................2 2.2. Aneminin Patofizyolojisi.....................................................................................................3 2.3. Anemilerin Sınıflandırılması ...............................................................................................4 2.3.i. Kemik İliği Yanıtına Göre Sınıflandırma.........................................................................5 2.3.2. Morfolojik Sınıflandırma..................................................................................................6 2.3.3. Patofizyolojik Sınıflandırma...........................................................................................i0 2.3.3.i. Rejeneratif Anemiler ...................................................................................................i0 2.3.3.2. Nonrejeneratif Anemiler..............................................................................................i2 2.4. Aneminin Klinik Özellikleri..............................................................................................i5 2.5. Anemilerde Laboratuvar Bulguları....................................................................................i6 2.6. Demir Metabolizması ........................................................................................................i8 iv 2.6.i. Demirin Fizyolojik Rolü.................................................................................................i9 2.6.2. Vücutta Dağılımı ............................................................................................................i9 2.6.3. Demir Regülasyonu ........................................................................................................20 2.6.4. Demir Profilinin Değerlendirilmesi................................................................................2i 2.7. Hepsidin.............................................................................................................................24 2.8. Demir Metabolizma Bozukluklarında Profil .....................................................................29 2.9. Köpeklerde Önceki Hepsidin Çalışmaları .........................................................................3i 3. GEREÇ VE YÖNTEM.........................................................................................................35 3.i. Hayvan Materyali ..............................................................................................................35 3.2. Yöntem ..............................................................................................................................37 3.2.i. Muayene Protokolü ve Alt Gruplandırma ......................................................................37 3.2.2. Laboratuvar Analizler.....................................................................................................38 3.3. İstatistiksel Değerlendirme ................................................................................................42 4. BULGULAR ........................................................................................................................44 5. TARTIŞMA..........................................................................................................................54 6. SONUÇ VE ÖNERİLER......................................................................................................6i KAYNAKLAR.........................................................................................................................62 EKLER .....................................................................................................................................76 Ek i. ADÜ- HADYEK Raporu ................................................................................................76 Ek 2. Bilgi Onam Formu ..........................................................................................................77 EK 3. Hasta Gözlem Formu .....................................................................................................78 BİLİMSEL ETİK BEYANI......................................................................................................79 ÖZ GEÇMİŞ.............................................................................................................................8

    A bibliometric analysis of the performance of Water Research

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    [[abstract]]This paper presents a detailed chronological survey of papers published in the journal titled Water Research which started publication since 1967. This current investigation reviews publication patterns between 1967 and 2008. An analysis of the research performance according to publication output, distribution of words in article title, author keywords, and keywords plus. Performances of countries, institutes, and authors, including total, single, collaborative, first author, and corresponding author publications were analyzed. The most-frequently cited articles each year and the articles of the highest impact in 2008 were also reported. Results showed that ‘‘activated sludge’’ was the most frequently used author keyword, followed by ‘‘adsorption,’’ and ‘‘drinking water.’’ Authors from 114 different countries/territories published in the journal, with the most articles submitted by authors from the USA

    Acoustic mapping and monitoring of the seabed: From single-frequency to multispectral multibeam backscatter

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    With the increasing human activities in the marine environment, such as fisheries, dredging, coastal protection or construction of marine infrastructure, seabed sediment and habitat mapping have become highly relevant for the development of sustainable marine management strategies. Compared to traditional mapping methods, primarily based on bed sampling, multibeam echosounding belongs to the cutting-edge technology to time-efficiently acquire high-resolution bathymetric and backscatter (BS) data over large areas. Using classification methods to combine the acoustic data with ground-truthing, large-scale maps can be automatically and objectively produced, that enables to describe the distribution of benthic habitats or quantify marine resources. However, acoustic sediment classification still does not allow to discriminate between the entire heterogeneity of the seabed and is generally applied to a single multibeam echosounder dataset by means of revealing the seabed state only at a given time instant. Two challenging issues addressed within the scope of this thesis are summarized as: (1) Investigation on the applicability of repetitive multibeam (single-frequency) BS measurements for monitoring the seabed; and (2) Evaluation of the potential of multispectral BS to increase the acoustic discrimination between different seabed environments.Aircraft Noise and Climate Effect
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