1,697 research outputs found

    Inhibition of Dendritic Calcium Influx by Activation of G-Protein–Coupled Receptors in the Hippocampus

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    Chen, Huanmian and Nevin A. Lambert. Inhibition of dendritic calcium influx by activation of G-protein–coupled receptors in the hippocampus. J. Neurophysiol. 78: 3484–3488, 1997. Gi proteins inhibit voltage-gated calcium channels and activate inwardly rectifying K+ channels in hippocampal pyramidal neurons. The effect of activation of G-protein–coupled receptors on action potential-evoked calcium influx was examined in pyramidal neuron dendrites with optical and extracellular voltage recording. We tested the hypotheses that 1) activation of these receptors would inhibit calcium channels in dendrites; 2) hyperpolarization resulting from K+ channel activation would deinactivate low-threshold, T-type calcium channels on dendrites, increasing calcium influx mediated by these channels; and 3) activation of these receptors would inhibit propagation of action potentials into dendrites, and thus indirectly decrease calcium influx. Activation of adenosine receptors, which couple to Gi proteins, inhibited calcium influx in cell bodies and proximal dendrites without inhibiting action-potential propagation into the proximal dendrites. Inhibition of dendritic calcium influx was not changed in the presence of 50 μM nickel, which preferentially blocks T-type channels, suggesting influx through these channels is not increased by activation of G-proteins. Adenosine inhibited propagation of action potentials into the distal branches of pyramidal neuron dendrites, leading to a three- to fourfold greater inhibition of calcium influx in the distal dendrites than in the soma or proximal dendrites. These results suggest that voltage-gated calcium channels are inhibited in pyramidal neuron dendrites, as they are in cell bodies and terminals and thatG-protein–mediated inhibition of action-potential propagation can contribute substantially to inhibition of dendritic calcium influx. </jats:p

    Paroles de Bernard Lambert : un paysan révolutionnaire

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    Le texte publié est la transcription des paroles prononcées par Bernard Lambert le 4 mai 1981 au séminaire « Luttes dans et pour l'espace rural » de Françoise Bourquelot et Nicole Mathieu à l'EHESS. Un récit de trente ans d'histoire du syndicalisme paysan, qui montre une pensée d'avant-garde, une ouverture sur les problèmes internationaux, une capacité de se projeter dans l'avenir. A former union member testimony and commitment The history of French farmers' unions since thirty years is related by Bernard LAMBERT (1931-1984), a long-time trade unionist, founder member of the union « Paysans travailleurs » and author of the book entitled Les paysans dans la lutte des classes (1970). Bernard LAMBERT's talk to a seminar held in Paris on May 4th 1981 at the EHESS, reveals, through debates put back in their context, his avant-garde ideas, his concern for international problems and his will to anticipate the future

    The Night has a Thousand Eyes. / Words by / F. W. BOURDILLON. / Music by / FRANK LAMBERT.

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    Box no. 6Lambert's lifedates according to https://imslp.org/index.php?title=Category:Lambert,_Frank&oldid=2748425; published in the series "Series of Short Songs"Frank Lambert: The Night Has a Thousand Eyes; Series of Short Songs; Chappell & Co. Ltd.; music printItem type: book | Content type: music | Writing material: black ink | Counting of pages: page numbersVocal-instrumental score | staff notation | voice; piano"The night has a thousand eyes, the day but one [...]

    Youth incarceration: A look behind locked doors

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    Douglas College and the New Westminster Museum collaborated to host the Tick-Talk: Crime and Consequences Student Conference, which featured criminology students' presentations on a variety of crime, justice, and social issues. Adopting a fast-paced presentation format, students raised key issues and challenges, described personal experiences, and disseminated unique ideas in a public forum. Presentation topics included the right to legal representation, the over-representation of Indigenous peoples in Canada’s criminal justice system, youth justice policy, and connections between mental health and criminal justice. The conference also included several discussion sessions that generated valuable dialogue among students, academics, practitioners, and members of the public. --- Rebecca Lambert presented on youth incarceration and the reality for troubled youth within Canada's youth criminal justice system. Lambert argued that incarcerated youth are not being adequately prepared for reintegration, and called for appropriate disciplinary measures, transition and reintegration programs, and further resources to help incarcerated youth develop personally and professionally.Not peer reviewe

    Emblemes sacrez sur le tres-saint et tres-adorable sacrement de l'eucharistie.

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    Signatures: pi² [dagger]⁴ A-M⁸ N⁶.The "embleme dedicatoire" and 100 numbered emblems were etched by Albert Flamen. See Landwehr."Acheué d'imprimer pour la premiere fois le 20. Ianuier 1666"--Colophon.Chesneau identified as author in censors' permission and in privilege. His Orpheus eucharisticus (published by Lambert in 1657) was translated into French and shortened by Augustin Lubin.Landwehr, J. French, Italian, Spanish and Portuguese emblem books,Mode of access: Internet.Binding: polished calfskin, tooled in gilt (early 19th century?). Title & artist's name on spine in gilt. Edges gilt. Green ribbon place marker

    Syringomatous Eccrine Carcinoma of the Vulva

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    Background: Skin adnexal neoplasms of the vulva are uncommon, and malignant adnexal neoplasms of the vulva are rare. Case: A case of syringomatous eccrine carcinoma arising in the perineum is presented, and the literature reviewed. Conclusions: Non-squamous malignancy of the vulva should be considered. All suspicious lesions of the vulva should be biopsied.Peer reviewe

    Re-envisioning Cyprus

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    Exhibition catalogue / edited volumeArtists and academics join forces in a common effort to “re-envision” Cyprus. The result is anedited volume and a photography & multimedia exhibition. The authors of “Re-envisioning Cyprus” come from different disciplines – such asanthropology, social sciences, art history, literature, cultural theory and visual arts. They usevarious methods – some excavate past images, and some produce or comment on newones. They exploit all kinds of materials – such as press, studio or vernacular photos, statues,landmarks, urban constructions and religious spaces. What united them is first their wish tosee Cyprus with their own eyes and with their own minds, rather than through officialisinglenses, or narratives. Second, they are rather interested in photography, and how it can helpour conceptual understanding of the island. The images each author has selected or produced will be included in the accompaniedexhibition. The exhibition will feature the work of visual artists from Cyprus and abroad andwill be opened by the Minister of Education and Culture, Mr. Andreas Demetriou onWednesday, December 8th at 8pm. Participating Authors and Artists: Loucas Antoniou, Melita Couta, Johanna Diehl, AnandanaKapur, Phanos Kyriacou, Orestis Lambrou, Chrystalleni Loizidou, Peter Loizos, MiriamPaeslack, Haris Pellapaisiotis, Nicos Phillipou, Sondra Sainsbury, Stefanos Stefanides,Theopisti Stylianou-Lambert, Constantinos Taliotis, Demetris Taliotis and Ellene Tsangarides. The exhibition is organized by the University of Nicosia (organizer) and the Cyprus Universityof Technology (partner) and is part of the celebration of the 50th year anniversary of Cyprus.The book is published by the University of Nicosia Press and will be available at theexhibition opening. Editors/ Curators:Peter Loizos (London School of Economics)Nicos Philippou (University of Nicosia)Theopisti Stylianou-Lambert (Cyprus University of Technology)Government of Cyprus, University of Nicosi

    Lambert, Hendricks & Ross: American ventriloquism

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    It has been fifty-one years since the last Lambert, Hendricks & Ross studio recording. Since then Dave Lambert was tragically killed on the Connecticut Turnpike, Jon Hendricks has become a University of Toledo professor, and Annie Ross is still performing frequently worldwide. Few jazz vocalists are accepted into the scholastic canon. Fewer are filed in the annals of music history. But, if any vocalists should be regarded important to the story of jazz music it is LHR. Their impact on the art of vocalese has yet to be fully felt. In exploring the motivation behind the group’s dense, meticulous, trailblazing recordings, this study attempts to be a supplement for what was too much for liner notes in the late 50’s and 60’s, while simultaneously giving a brief encompassing historical outline. By examining the social and musical impact of Lambert Hendricks & Ross, this study attempts to further legitimate the art of jazz vocals and vocalese.M.A.Includes bibliographical referencesIncludes vitaby Bilal Salaa

    Using quantitative data

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    This is an Accepted Manuscript of a book chapter published by Routledge/CRC Press in Practical research methods in education : an early researcher's critical guide on 26 February 2019, available online: https://www.routledge.com/Practical-Research-Methods-in-Education-An-Early-Researchers-Critical/Lambert/p/book/9780815393566The intention of this chapter is to demystify quantitative research and give readers clear, straightforward information about collecting and analysing quantitative data. It does this by clarifying key concepts and terms and illustrating these with examples taken from the author’s own research and other investigations. The chapter first explains the concepts of independent, dependent and other variables and why controlling them is important. Three types of quantitative design are then considered: experiments, quasi-experiments and non-experiments, together with notions of internal and external validity. The purposes and limitations of randomized control trials (RCTs) are examined, again with critical reference to real research. In discussing data analysis, readers are introduced to important concepts, including descriptive statistics, central tendency and standard deviation, as well as inferential statistics, statistical significance, effect size, correlation and factor analysis. To conclude, the author recommends that improving the understanding of quantitative data can help all researchers to assess quantitative investigations more critically and to integrate use into their own research projects

    Kublai Khan and the Sun Bird: A Fairy Tale

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    Reminiscent of H. C. Andersen’s “The Emperor and the Nightingale,” this original literary fairy tale by the contemporary Canadian author Shaena Lambert is published here for the first time
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