1,721,346 research outputs found
Concomitant medications and immune checkpoint inhibitor therapy for cancer: causation or association?
The majority of cancer patients assume concomitant medications for the treatment of cancer-related symptoms or co-morbidities. As immune checkpoint inhibitors expand in the treatment of a widening range of malignancies, drug–drug interactions have become an area of increasing interest due to the potential for some concomitant medications to exert immune-modulatory effects and influence outcomes from immunotherapy. Here, we review the evidence supporting this association across selected drug classes including antibiotics, proton pump inhibitors, metformin, and opioids
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Is FinTech providing effective solutions to Small and Medium Enterprises (SMEs) in ASEAN countries?
With the continuous boom of FinTech, the similar features of different platforms provide effective solutions for small and medium enterprises. This study examines whether FinTech offers useful business mechanisms for SMEs in selected ASEAN countries. The ASEAN countries included in the study are Indonesia, Malaysia, Philippine, Singapore, and Thailand. The study employed factor analysis and segregated the FinTech-SME nexus into five factors. The responses of 300 SME owners were collected through interview questionnaires and surveys. We find that new FinTech and SMEs 'collisions' (our term for new utilization) during COVID-19 are the most important factors in the growth of FinTech and the strength of SMEs. Further, we utilized the Kruskal-Wallis test to validate our results and for ranking the factors alongside the ASEAN countries. We present useful implications for policymakers, regulatory bodies, ASEAN countries, and SMEs for welcoming FinTech solutions to facilitate digital transactions. (c) 2022 Economic Society of Australia, Queensland. Published by Elsevier B.V. All rights reserved
Modelling systemic risk of energy and non-energy commodity markets during the COVID-19 pandemic
COVID-19 led restrictions make it imperative to study how pandemic affects the systemic risk profile of global commodities network. Therefore, we investigate the systemic risk profile of global commodities network as represented by energy and nonenergy commodity markets (precious metals, industrial metals, and agriculture) in pre- and post-crisis period. We use neural network quantile regression approach of Keilbar and Wang (Empir Econ 62:1–26, 2021) using daily data for the period 01 January 2018–27 October 2021. The findings suggest that at the onset of COVID-19, the two firm-specific risk measures namely value at risk and conditional value of risk explode pointing to increasing systemic risk in COVID-19 period. The risk spillover network analysis reveals moderate to high lower tail connectedness of commodities within each sector and low tail connectedness of energy commodities with the other sectors for both pre- and post-COVID-19 periods. The Systemic Network Risk Index reveals an abrupt increase in systemic risk at the start of pandemic, followed by gradual stabilization. We rank commodities in terms of systemic fragility index and observe that in post COVID-19 period, gold, silver, copper, and zinc are the most fragile commodities while wheat and sugar are the least fragile commodities. We use Systemic Hazard Index to rank commodities with respect to their risk contribution to global commodities network. During post COVID-19 period, the energy commodities (except natural gas) contribute most to the systemic risk. Our study has important implications for policymakers and the investment industry
Return and volatility spillovers between energy and BRIC markets: Evidence from quantile connectedness
Using the quantile connectedness approach for the median, lower, and upper quantiles, we examine the return and volatility connectedness between energy and BRIC markets from January 1, 2000, to July 9, 2021. We find that uncertain economic activity and intense periods characterize energy and BRIC market returns and volatility connectedness. A parallel return and volatility connectedness structure for upper and lower quantiles against the average quantile revealed different results. Time-varying features are substantiated between energy and BRIC markets; significant distress events, such as the Global Financial Crisis, European Debt Crisis, Shale Oil Revolution, and COVID-19 pandemic, intensified spillovers. We highlight diversification avenues for energy and BRIC markets given the periods of financial turmoil, with investors' concerns widely addressed by opt-in investment opportunities with lower risk and greater diversification. Our study has beneficial implications for policymakers, regulators, investors, and financial market constituents to redevelop their existing strategies to avoid financial losses
Board gender diversity and sustainable growth rate: Chinese evidence
This study investigates the impact of women directors on a firm’s sustainable growth rate. Using data from 2003 to 2017 for Chinese listed firms, we found a positive relationship between women directors and a sustainable growth rate. Our study also contributes to institutional theory by providing evidence that this positive relationship is more effective in legal-person-controlled firms than state-controlled firms. In comparison, women independent directors have a stronger influence than women executive directors on sustainable growth. Similarly, board gender diversity with three or more female directors substantially affects firms’ sustainable growth, consistent with critical mass theory. Our study’s findings are robust in terms of alternative estimations techniques, variable specifications, and different identification strategies, such as two-stage least squares and propensity score matching. Our study provides novel evidence on women directors’ role in increasing firms’ sustainable growth rate by adding a new dimension to the ongoing debate in the gender diversity literature
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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